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EPIDEMIOLOGICAL STUDIES ON ETIOLOGY OF LIVER FUNCTION TEST ABNORMALITIES IN WORKERS -SPECIAL REFERENCE TO HEPATITIS VIRUS TYPE C INFECTION

Research Project

Project/Area Number 03454212
Research Category

Grant-in-Aid for General Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field 公衆衛生学
Research InstitutionTOKAI UNIVERSITY (1992)
Keio University (1991)

Principal Investigator

OKAZAKI Isao  TOKAI UNIVERSITY SCHOOL OF MEDICINE DEPARTMENT OF COMMUNITY HEALTH, PROFESSOR, 医学部, 教授 (00051649)

Co-Investigator(Kenkyū-buntansha) OSAKA Fumio  TOKAI UNIVERSITY SCHOOL OF MEDICINE DEPARTMENT OF COMMUNITY HEALTH, ASSISTANT PR, 医学部, 講師 (70096204)
YOSIDA Katsumi  KEIO GIJUKU UNIVERSITY SCHOOL OF MEDICINE, DEPARTMENT OF PUBLIC HEALTH, ASSOCIAT, 医学部, 助教授 (80158435)
伊津野 孝  慶應義塾大学, 医学部, 助手 (20213019)
Project Period (FY) 1991 – 1992
Project Status Completed (Fiscal Year 1992)
Budget Amount *help
¥4,700,000 (Direct Cost: ¥4,700,000)
Fiscal Year 1992: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1991: ¥3,700,000 (Direct Cost: ¥3,700,000)
KeywordsIndustrial health / HCV infection / Liver disease / 健康管理 / C100-3抗体 / 職場の健康管理 / 肝機能検査 / HBVキャリア- / HCVキャリア- / アルコ-ル性肝障害
Research Abstract

In order to investigate the etiology of the abnormalities in liver function tests among workers, 800 workers in some workplace were extensively examined. It revealed that Hepatitis B virus (HBV) carrier 7%, Hepatitis C virus antibody (c100-3 antibody) positive 11%, alcoholic liver diseases 19%, marked obesity 30%, moderate alochol drink and/or moderate obesity 34% and unknown 1% were observed in workers who showed the abnormal liver function tests but the normal daily activity of both works and usual life. 350 workers in another workplace who received the pre-retirement health check revealed that 10% of workers with abnormal liver function tests had the positive antibody against HCV, and that workers without abnormal liver function tests showed negative except few. Therefore, the indication of C100-3 test should be for workers with liver function tests. The next problem is the role of HCV infection among workers with alcoholic liver diseases at the workplace. They were very different from the patients with alcoholic liver diseases in Kurihama National Hospital. The latter revealed that the HCV infection caused alcoholic liver diseases to severer state. But the former workers were not severe be-cause their drinking habit changed to a good improvement.

Report

(3 results)
  • 1992 Annual Research Report   Final Research Report Summary
  • 1991 Annual Research Report
  • Research Products

    (29 results)

All Other

All Publications (29 results)

  • [Publications] 岡崎 勲: "職場におけるアルコール依存症" 香川県医師会誌. 44. 32-36 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 岡崎 勲: "ウィルス性肝炎の最近の動向" 日本産婦人科学会埼玉地方部会誌. 22. 82-85 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 岡崎 勲: "職場におけるアルコール性肝障害とC型肝炎との関連" アルコール問題研究会誌. 3. 1-10 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 岡崎 勲,村田 友紀: "職場環境とアルコール依存" 労働の科学. 47. 310-313 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 岡崎 勲,村田 友紀,和田 則仁: "職場の環境要因「生物学的要因」" 公衆衛生. 56. 461-464 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 岡崎 勲: "これからの健康管理ーがん、心臓病、肝臓病、糖尿病、ストレスの一次予防を中心にー" 日本医事新報社, 181 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 岡崎 勲: "これからの健康管理ーがん、心臓病、肝臓病、糖尿病、ストレスの一次予防を中心にー改訂第2版" 日本医事新報社, 197 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Okazaki,I.: "Alcoholism in occupational health." J. Kagawa Prefecture Medical Association. 44. 32-36 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Okazaki,I.: "Recent trend on viral hepatitis." J. Saitama Prefecture Gynecologists Association. 22. 82-85 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Okazaki,I.: "The relation between alcoholic liver diseases and type C hepatitis." Archive of Alcohol Problem Research. 3. 1-10 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Okazaki,I. and Murata,Y.: "Occupational Environment and Alcoholism." J. Science of Labour. 47. 310-313 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Okazaki,I., Murata,Y. and Wada,N.: "Biological hazards in occupational environment." Public Health. 461-464 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Okazaki,I.: Ijishinnpousha Pub. Co.Primary Health Care -for the primary prevention of cancer, cardiac disease, liver disease, diabetes mellitus and stress-, 181 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Okazaki,I: Ijishinnpousha Pub. Co.Primary Health Care-for the primary prevention of cancer, cardiac disease, liver disease, diabetes mellitus and stress, 2nd Edition, 197 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 岡崎 勲: "職場におけるアルコール依存症" 香川県医師会誌. 44. 32-36 (1991)

    • Related Report
      1992 Annual Research Report
  • [Publications] 岡崎 勲: "ウィルス性肝炎の最近の動向" 日本産婦人科学会埼玉地方部会誌. 22. 82-85 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 岡崎 勲: "職場におけるアルコール性肝障害とC型肝炎との関連" アルコール問題研究会誌. 3. 1-10 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 岡崎 勲、村田 友紀: "職場環境とアルコール依存" 労働の科学. 47. 310-313 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 岡崎 勲、村田 友紀、和田 則仁: "職場の環境要因「生物学的要因」" 公衆衛生. 56. 461-464 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 岡崎 勲: "これからの健康管理ーがん、心臓病、肝臓病、糖尿病、ストレスの一次予防を中心にー" 日本医事新報社, 181 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 岡崎 勲: "これからの健康管理ーがん、心臓病、肝臓病、糖尿病、ストレスの一次予防を中心にー改訂第2版" 日本医事新報社, 197 (1993)

    • Related Report
      1992 Annual Research Report
  • [Publications] 岡崎 勲: "某事業所における肝機能異常者のC型肝炎汚染度" 第64回日本産業衛生学会講演集. 135 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 岡崎 勲: "アルコ-ルと肝線維化" 医学のあゆみ. 154. 921-925 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 岡崎 勲: "肝線維化マ-カ-:血清PIIIP" Gastro. 1. 105-112 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 岡崎 勲: "職場におけるアルコ-ル依存症" 香川県醫師会誌. 44. 32-36 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 岡崎 勲: "ウィルス性肝炎の最近の動向" 埼玉県醫師会誌. (1992)

    • Related Report
      1991 Annual Research Report
  • [Publications] 岡崎 勲: "職場における肝機能異常者の成因に関する疫学的研究" 日本公衆衛生雑誌. 39. (1992)

    • Related Report
      1991 Annual Research Report
  • [Publications] 岡崎 勲: "これからの健康管理ーがん、心臓病、肝臓病、糠尿病、ストレスの一次予防を中心にー 第2刷" 日本醫事新報社, 181 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 岡崎 勲: "Annual Review 消化器 1991(分担)" 中外医学社, 143-150 (1991)

    • Related Report
      1991 Annual Research Report

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Published: 1991-04-01   Modified: 2016-04-21  

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