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BASIC RESERCH FOR APPLICATION OF VARYING MAGNETIC STIMULATION

Research Project

Project/Area Number 03454458
Research Category

Grant-in-Aid for General Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field 外科・放射線系歯学
Research InstitutionTOKYO MEDICAL AND DENTAL UNIVERSITY

Principal Investigator

UMINO Masahiro  TOKYO MEDICAL AND DENTAL UNIVERSITY FACULTY OF DENTISTRY ASSOCIATE PROFESSOR, 歯学部, 助教授 (90014125)

Co-Investigator(Kenkyū-buntansha) ODA Nobuo  SEITOKU UNIVERSITY DEPARTMENT OF CULTURAL SCIENCES PROFESSOR, 人文学部, 教授 (30016844)
Project Period (FY) 1991 – 1993
Project Status Completed (Fiscal Year 1993)
Budget Amount *help
¥6,300,000 (Direct Cost: ¥6,300,000)
Fiscal Year 1993: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1992: ¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 1991: ¥4,000,000 (Direct Cost: ¥4,000,000)
KeywordsVARYING MAGNETIC FIELD / DIELECTRIC CONSTANT / ELECTRODE POLARIZATION / alpha DISPERSION / BLOOD / 血液 / 細胞膜 / 分散 / 変動電場 / 周波数 / 誘電緩和 / 誘導起電力 / 血液インピ-ダンス
Research Abstract

1) Dielectric constants of blood samples have been first measured in the frequency region, 20Hz-30MHz, by the two electrode method. Samples were human whole blood, plasma, lysed er-ythrocytes, packed red cells, the interior solution of erythrocytes, and the physiological saline. Dielectric constants of samples were derived from the capacitances measured.
From this result, it was found that the contribution of the electrode polarization to me-asured values of dielectric constants was considerable in the low frequency region, that is the alpha-dispersion region. Then, in order to eliminate the effect of the electrode polarization, dielectric constants were secondaly measured by the four electrode method, result-ing in that the effect of the electrode polarization is greatly reduced in the low frequency region ((〕SY.ltoreq.〔) 10KHz). Comparing measured values of dielectric constants of six samples, it is concluded that (1) the so - called alpha-dispersion in low frequencies is mostly due to the electrode polarization and is not real, and (2) the so - called beta-dispersion is due to the structural dispersion as pointed out before.
2) Relation between electrode polarization and intensity of electric field was investigated in iontophoresis. Samples were 1 % of xylocaine and physiological saline. Potential difference in medium was decreased by delivering direct current. Marked decrease of potential difference was observed under constant voltage. Decrease of potential difference was due to electrode polarization. It is possible to improve iontophoresis by blocking electrode polarization.

Report

(4 results)
  • 1993 Annual Research Report   Final Research Report Summary
  • 1992 Annual Research Report
  • 1991 Annual Research Report
  • Research Products

    (18 results)

All Other

All Publications (18 results)

  • [Publications] 海野雅浩: "変動磁場曝磁下の血液内誘導渦電流の測定とマッピング" 日本生体磁気学会誌. 4. 124-125 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Umino,M.: "Measurement of eddy current in blood induced by varying magnetic field." J.Int.Fed.Med.Biol.Engi.29. 1192 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 海野雅浩: "変動磁場曝磁下の組織内誘導電流の解析-交流通電下の血液インピーダンスの挙動-" 日本生体磁気学会誌. 5. 150-153 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 海野雅浩: "血液誘電率の周波数特性に及ぼす赤血球膜の影響" 医用電子と生体工学. 31. 246 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Oda,N.: "Electric characteristics in the tissue-the frequency dependence of dielectric constant in blood." J.Rad.Res.34. 408 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 海野雅浩: "Iontophoresis効率化の試み-電気分極と媒質内電界強度の関係" 日本歯科麻酔学会誌. 21. 159 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Masahiro Umino: "Mapping and measurement of induced eddy current in blood under exposure of varying magnetic field" J.Jap. Biomag. Bioelect. Soc.4. 124-125 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Masahiro Umino: "Measurement of eddy current in blood induced by varying magnetic field" J.Int. Fed. Med. Biol. Engi.29. 1192 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Masahiro Umino: "Analysis of induced current in tissue under varying magnetic field." J.Jap. Biomag. Bioelect. Soc.5. 150-153 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Masahiro Umino: "Effects of erythrocytes membrane on characteristics of dielectric constants in blood." J.J.ME.31. 246 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Nobuo Oda: "Electric characteristics in the tissue-The frequency dependence of dielectric constant in blood-." J.Rad. Res.34(4). 408 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Masahiro Umino: "Attempt of improvement of iontophoresis-Relation between electrode polarization and intensity of electric field in medium-." J.Jap. Dent. Soc. Anest.21. 159 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 海野雅浩: "血液誘電率の周波数特性に及ぼす赤血球膜の影響" 医用電子と生体工学. 31. 246 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 海野雅浩: "Iontophoresisの効率化の試み-電極分極と媒質内の電解強度の関係-" 日本歯科麻酔学会雑誌. 21. 92 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 海野 雅浩 安原 愛明 織田 暢夫: "変動磁場曝磁下の組織内誘導電流の解析 ー交流通電下の血液インビーダンスの挙動ー" 日本生体磁気学会誌. 5. 150-153 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 海野 雅浩 安原 愛明: "変動電磁場の歯科領域の応用に関する基礎的研究" 日本歯科麻酔学会誌. 21. 202- (1993)

    • Related Report
      1992 Annual Research Report
  • [Publications] 海野 雅浩,安原 愛明,織田 暢夫: "変動磁場曝磁下の血液内誘導渦電流の測定とマッピング" 日本生体磁気学会誌. 4(1). 124-125 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 海野 雅浩,安原 愛明,織田 暢夫: "変動磁場曝磁による組織的誘導電流の分布に関する研究" 日本歯科麻酔学会雑誌. 19. 54 (1991)

    • Related Report
      1991 Annual Research Report

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Published: 1991-04-01   Modified: 2016-04-21  

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