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Neiuromagnetic study on speech sound processing in human auditory cortex

Research Project

Project/Area Number 03455002
Research Category

Grant-in-Aid for General Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field 広領域
Research InstitutionHokkaido University

Principal Investigator

KURIKI Shinya  Hokkaido Univ., Resarch Inst. for Electronic Sci., Professor, 電子科学研究所, 教授 (30002108)

Co-Investigator(Kenkyū-buntansha) KOBAYASHI Tetsuo  Hokkaido Univ., Resarch Inst. for Electronic Sci., Assistant Prof., 電子科学研究所, 講師 (40175336)
MATSUSHIMA Jyunichi  Hokkaido Univ., Medical School, Assistant Prof., 医学部, 講師 (60173829)
IFUKUBE Toru  Hokkaido Univ., Resarch Inst. for Electronic Sci., Professor, 電子科学研究所, 教授 (70002102)
Project Period (FY) 1991 – 1992
Project Status Completed (Fiscal Year 1992)
Budget Amount *help
¥4,200,000 (Direct Cost: ¥4,200,000)
Fiscal Year 1992: ¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 1991: ¥2,200,000 (Direct Cost: ¥2,200,000)
KeywordsNeuromagnetic Field / SQUID / Auditory Cortex / Voice Processing / Auditory Evoked Field
Research Abstract

We have been studied the neural activities in the human auditory cortex concerning with the speech sound processing by measuring neuromagnetic fields. Obtained results are summarized as follows.
1. Background noises in the auditory evoked magnetic field responses recorded with a 37 channel SQUID magnetometer have been studied. The background noise was found to have a main contribution from the spontaneous fields, which originate in the neural activities of the brain. The spontaneous fields had strong spatial correlation across the recording sites even after averaging over 100 epochs. Furthermore, the signal to noise ratio, which is needed for accurate source localization, was determined from the experiments.
2. The relationship between tinnitus and auditory neural activities was studied based on the neuromagnetic fields. It was found that either Nlm or Plm component increases due to the suppression of tinnitus by electrical stimulation to cochlea under some circumstances.
3. Neuromagnetic fields evoked by monosyllable speech sounds, i.e. /a/, /ka/, /ha/ and /na/, have been measured using a 37 channel SQUID magnetometer. Parameters of a dipole current source have been estimated using several sets of field data recorded in different measurement runs. It was found from the results that statio-temporal movements of the sources depend on the subjects as well as stimuli. However, the sources of N1m components evoked by /a/ and /na/ commonly move either to anterior, medial or posterior direction in all subjects.

Report

(3 results)
  • 1992 Annual Research Report   Final Research Report Summary
  • 1991 Annual Research Report
  • Research Products

    (41 results)

All Other

All Publications (41 results)

  • [Publications] 栗城 真也: "多チャンネルSQUID磁束計による聴覚誘発脳磁界の観測" 日本音響学会誌. 48. 320-327 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] O.Oshro,M.Mukai,F.Takeuchi and S.kuriki: "Analysis of errors on neuromagnetic localization of multiple current dipole sources" Phys.Med.Biol.37. 845-852 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 竹内 文也,栗城 真也: "誘発脳磁図の計測と電源推定" 日本ME学会誌. 6. 28-43 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] S.Kuriki: "Localization of cortical neuromagnetic sources of the auditory evoked responses to short speech sounds" Biomed.Res.13. 39-43 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] S.Kuriki,F.Takeuchi and T.Kobayashi: "Dynamic characteristics of neuromagnetic fields evoked by vowel speech sound" Proc.Satel.Symp.Neurosci.Technol.,14th Ann.Int.Conf.IEEE EMB Soc.99-103 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 坂尻 正次,平田 恵啓,伊福部 達,泉 隆,永井 謙芝,松島 純一,藤村 裕,原田 千洋: "人工内耳を利用した耳鳴抑制装置" 電子情報通信学会技術研究報告. MBE92-46. 57-62 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 竹内 文也,栗城 真也: "37チャンネルSQUIDによるCV刺激誘発脳磁界の動的特性" 第7回生理生体工学シンポジウム論文集. 423-428 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 栗城 真也,竹内 文也: "脳磁図ー聴覚誘発反応を中心としてー" nanoGIGA. 1. 513-515 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 栗城 真也: "聴覚誘発MEG" Clinical Neuroscience. 11. 200-202 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] M.Sakajiri,Y.Hirata.T.Izumi,T.Ifukube and J.MAtsushima: "A method for suppressing tinnitus by electrical stimulation to cochlea and a remedial value" J.Acoust.Soc.Japan(E).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] T.Kobayashi,M.Ii and S.Kuriki: "Analysys of neuromagnetic fields generated by a current dipole Source" Applied Electromagnetics in Materials and Computational Technology ed.,t.Honma et al.,Hokkaido univ.Press.13-16 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] F.Takeuchi,M.Mukai,S.kuriki,M.Hayashi and T.Imada: "Spatio-temporal Source localization of neuromagnetic fields evoked by pure tones" Biomagnetism:clinicalaspects ed.,M.Hoke et al.,Elsevier.181-184 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] O.Oshiro,M.Mukai,F.Takeuchi and S.Kuriki: "Multiple dipole estimation by parameter search method" Biomagnetism:Clinicalaspects ed.,M.Hoke et al.,Elsevier.693-697 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 栗城 真也(分担執筆): "誘発電位(下地恒毅編第11章)" 西村書店, 13 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] O.Oshiro, M.Mukai, F.Takeuchi and S.Kuriki: "Analysis of errors on neuromagnetic sources of the auditory evoked responses" Phys. Med. Biol.Vol.6. 845-852 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] S.Kuriki: "Localization of cortical neuromagnetic sources of auditory evoked responses to short speech sounds" Biomed. Res.Vol.13, Suppl.1. 39-43 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] S.Kuriki, F.Takeuchi and T.Kobayashi: "Dynamic characteristics of neuromagnetic fields evoked by vowel speech sound" Proc. Satel. Symp. Neurosci. Technol., 14th Ann. Int. Conf. IEEE EMB Soc.99-103 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] F.Takeuchi, M.Mukai, S.Kuriki, M.Hayashi and T.Imada: "Spatio-temporal source localization of neuromagnetic fields evoked by pure tones" Biomagnetism: Clinical Aspects, ed. by M.Hoke et al. Elsevier. 181-184 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] O.Oshiro, M.Mukai, F.Takeuchi and S.Kuriki: "Multiple dipole estimation by parameter search method" Biomagnetism: Clinical Aspects, ed. by M.Hoke et al, Elsevier. 181-184 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] T.Kobayashi, M.Ii and S.Kuriki: "Analysis of neuromagnetic fields generated by a current dipole source" Applied Electromagnetics in Materials and Computational Technology, ed. by T.Honma et al, Hokkaido Univ. Press. 13-16 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] M.Sakajiri, Y.Hirata, T.Izumi, T.Ifukube and J.Matsushima: "A method for suppressing tinnitus by electrical stimulation to cochlea and a remedial value" J. Accost. Soc. Japan,(E).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 栗城 真也: "多チャンネルSQUID磁束計による聴覚誘発脳磁界の観測" 日本音響学会誌. 48. 320-337 (1990)

    • Related Report
      1992 Annual Research Report
  • [Publications] O.Oshiro,M.Mukai,F.Takeuchi and S.Kuriki: "Analysis of erroes on neuromagnetic localization of multiple current dipole sources" phys.Med.Biol.37. 845-852 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 竹内文也、栗城真也: "誘発脳磁図の計測と電源推定" 日本ME学会誌. 6. 28-43 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] S.kuriki: "Localization of cortical neuromagnetic sources of the auditory eveked responses to short speech sounds" Biomed.Res. 13. 39-43 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] S.kuriki,F.Takeuchi and T.Kobayashi: "Dynamic characteristics of neuromagnetic fields evoked by vowel speech sound." Proc.Satel, Symp.Neurosci. Technol., 14th Ann. Int. Conf. IEEE EMB Soc.99-103 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 坂尻正次.平田恵啓.伊福部達.泉隆.永井謙芝.松島純一.藤村裕.原田千洋: "人工内耳を利用した耳鳴抑制装置" 電子情報通信学会技術研究報告. MBE92-46. 57-62 (1990)

    • Related Report
      1992 Annual Research Report
  • [Publications] 竹内 文也.栗城真也: "37チャンネルSQUIDによるCV刺激誘発脳磁界の動的特性" 第7回生理生体工学シンポジウム論文集. 423-428 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 栗城 真也.竹内 文也: "脳磁図-聴覚誘発反応を中心として-" nano GIGA. 1. 513-515 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 栗城 真也: "聴覚誘発 MEG" Clinical Neuroscience. 11. 200-202 (1993)

    • Related Report
      1992 Annual Research Report
  • [Publications] M.Sakajiri,Y.Hirata,T.Izumi,T.Ifukube and J.Matsushima: "A method for suppressing tinnitus by electrical stimulation to cochlea and a remedial value" J.Acoust. Soc. Japan.(E).

    • Related Report
      1992 Annual Research Report
  • [Publications] T.Kobayashi,M.Ii and S.Kuriki: "Analysis of neuromagnetic fields generated by a current dipole source" Applied Electromagnetics in Materials and Computational Technology ed.,T.Honma et al., Hokkaido univ.Press.13-16 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] F.Takeuchi,M.Mukai,S.Kuriki,M.Hatashi and T.Imada: "Spatio-temporal source localization of neuromagnetic fields evoked by pure tones" Biomagnetism:Clinicalaspects ed.,M.Hoke et al., Elsevier.181-184 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] O.Oshiro,M.Mukai,F.Takeuchi and S.Kuriki: "Multiple dipole estimation by parameter search method" Biomagnetism:Clinicalaspects ed.,M.Hoke et al., Elsevier.693-697 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 栗城真也(分担執筆): "誘発電位(下地恒毅編 第11章)" 西村書店, 13 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 竹内 文也,栗城 真也: "聴覚誘発脳磁界応答の時空間解析法の検討" 電気学会研究会資料 MAG92ー77. 11-16 (1992)

    • Related Report
      1991 Annual Research Report
  • [Publications] 栗城 真也: "音声刺激による聴覚誘発脳磁界計測" 計測自動制御学会誌. 31. 294-299 (1992)

    • Related Report
      1991 Annual Research Report
  • [Publications] 大城 理,竹内 文也,栗城 真也: "脳磁界における複数の電流双極子の推定" 電気学会研究会資料 Vol.MAGー91ー215. 29-37 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 栗城 真也,竹内 文也: "CV刺激誘発脳磁界の活動源解析ー多チャンネルSQUIDによる計測ー" 第6回生体・生理工学シンポジウム論文集. 25-28 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] F.Takeuchi,M.Mukai,S.Kuriki,M.Hayashi,and T.Imada: "Spatioーtemporal source localization of neuromagnetic fields evoked by pure fones" 8th International Conference on Biomagnetism,(Munster,1991ー08)Abstracts. 147-149 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] O.Oshiro,M.Mukai,F.Takeuchi and S.Kuriki: "Multiple dipole estimation by parameter variation method" 8th International Conference on Biomagnetism,(Munster,1991ー08)Abstracts. 75-76 (1991)

    • Related Report
      1991 Annual Research Report

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Published: 1991-04-01   Modified: 2016-04-21  

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