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Trial for new cancer therapy by transfection of cytokine genes

Research Project

Project/Area Number 03670682
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Cerebral neurosurgery
Research InstitutionKYOTO UNIVERSITY

Principal Investigator

MIYATAKE Shin-ichi  Kyoto University, Faculty of Medicine, Instructor., 医学部, 助手 (90209916)

Co-Investigator(Kenkyū-buntansha) TASHIRO Yuzuru  Kyoto University, Faculty of Medicine, Instructor., 医学部, 助手 (40236518)
ODA Yoshifumi  Kyoto University, Faculty of Medicine, Assistant Professor, 医学部, 助手 (10026958)
Project Period (FY) 1991 – 1992
Project Status Completed (Fiscal Year 1992)
Budget Amount *help
¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 1992: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1991: ¥1,300,000 (Direct Cost: ¥1,300,000)
KeywordsBrain Tumor / Interleukin / Macrophage / Monoclonal Antibody / モノクローナル抗体 / サイトカイン / ILー7 / 遺伝子治療
Research Abstract

(1) Transfection of the interleukin 7 gene into brain tumor cells.
(2) Activation of macrophages' cytotoxity by cytokines.
(3) Imaging of brain tumas using glioma- specific monoclonal antibodies

Report

(3 results)
  • 1992 Annual Research Report   Final Research Report Summary
  • 1991 Annual Research Report

Research Products

(9 results)

All Other

All Publications (9 results)

  • [Publications] 青木 友和: "Expussion of murine interleukin 7 in a 203-glioma cell line results in seduced tumorigen." Proc.Natl.Acad.Sci.USA. 89. 3850-3854 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 近藤 精二: "Human Glioma-Specific Antigens Detected by Monoclanal Antibodies" Nearosurgery. 30. 507-511 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Tomokazu Aoki: "Expression of murine interleukin 7 in a 203- glioma cell line results in reduced tamorigen" Proc. Natl. Acad. Si. USA. 80. 3850-3854 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Seiji Kondo: "Human Glioma- specific Antigens Detected by Monoclonal Antibodies" Neurosurgery. 30. 507-511 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 青木 友和: "Exprission of murine interleukin 7 in a 203-glioma cell line results in reduced tumorigen" Proc Natl.Acad.Sci.USA. 89. 3850-3854 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 近藤 精二: "Human Glioma-specific Antigens Detected by Moroclonal Antibodies" Neurosurgery. 30. 507-511 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] Aoki .,Tashiro K,Miyctche S,et al.: "Expression of murine interleakin 7 in a 203ーglione cell line reaults in reduced tumorsgenicity in vio." Proc.Nctl.Acad.Sci.USA.

    • Related Report
      1991 Annual Research Report
  • [Publications] 青木 友和,宮武 伸一,織田 祥史: "脳腫瘍の遺伝子療法" Annual Reriew神経1992. 195-202 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 宮武 伸一,近藤 精二,青木 友和,他: "標的細胞のインタ-フェロン処理による細胞内免疫に対する感受性の変化(腫瘍特異的CTLクロ-ンおよびLAK細胞を用いた解析)" 脳神経外科. 19. 1053-1059 (1991)

    • Related Report
      1991 Annual Research Report

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Published: 1991-03-31   Modified: 2016-04-21  

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