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Immunohistochemical Analysis of Pseudomembirane surrrocending mouse DMBA-induced malignant fibrous histiocytoma

Research Project

Project/Area Number 03670695
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Orthopaedic surgery
Research InstitutionYamagata University

Principal Investigator

WATANABE Yoshihiro  Yamagata Univ.Sch.of Med., Prof., 医学部, 教授 (90018359)

Co-Investigator(Kenkyū-buntansha) SATO Takashi  Yamagata Univ.Sch.of Med., Instructor, 医学部, 助手 (40240676)
SUDA Akio  Yamagata Univ.Sch.of Med., Associate Prof., 医学部, 助教授 (80045715)
Project Period (FY) 1991 – 1993
Project Status Completed (Fiscal Year 1993)
Budget Amount *help
¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1993: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 1992: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 1991: ¥700,000 (Direct Cost: ¥700,000)
KeywordsPseudo membrane / Anti-tumor reaction / Immunohistochemistry / scid mouse / bone and soft tissue tumors / 免疫組織学 / スキッドマウス / MFH(悪性線維性組織球腫) / 僞被膜
Research Abstract

In this year we established tumor transplantation systems toward SCID mouse and NUDE mouse. Administrations of anti-neoplastic agenys, mainly Cis-platin (CDDP), did not strengthen the formation of pseudomembrane in any SCID mouse transplanted tumor system.
In some cases of NUDE mouse system, the formation of inflammatory zone was streng thened. We planed and are making the inplantation of bone nurrow cells into peritoneal space.

Report

(4 results)
  • 1993 Annual Research Report   Final Research Report Summary
  • 1992 Annual Research Report
  • 1991 Annual Research Report
  • Research Products

    (22 results)

All Other

All Publications (22 results)

  • [Publications] 須田昭男: "骨軟部腫瘍に対する201Tl-chlorideシンチグラフィの有用性" 日本整形外科学会雑誌. 67. S1117- (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 小山内俊久: "繊維増生著名な悪性顆粒細胞腫の一例" 日本整形外科学会雑誌. 67. S1003- (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 石川朗: "大腿骨悪性腫瘍に対する人工膝関節置換症例のcybex-IIによる筋力評価" 日本整形外科学会雑誌. 67. S1053- (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 加藤博文: "頭蓋内、軟部組織、腸管への転移を生じた悪性線維性組織球腫の一例と治療に伴うPCNA発現率の変動" 日本整形外科学会雑誌. 67. S1138- (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 三浦由太: "Inflammatomy cells in the rseudocapsule of osteosarcoma" Clinical Orthopaedics related research. 300. 225-252 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Suda A.et al.: "201 TL scintiyraphy for bone and soft tissue tumors" J.Jpn.Orthop.Assoc.67. S1117 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Osanai T.et al.: "A case of malignant gramlar cell tumor - value of MRI and DNA cytoffuorometey-" J.Jpn.Orthop.Assoc.67. S1003 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Ishikawa A.et al.: "The evaluation of the muscle power by using Cybex II to cases of TKR which were done to the malignant tumors of the femur" J.Jpn.Orthop.Assoc.67. S1053 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Kato H.et al.: "A case of Malignant fibrous histiocytoma with metastasis of intra cranium soft tissue and intestine and a study of relationship between PCNA labedling index and treatment" J.Jpn.Orthop.Assoc.67. S1053 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Miura Y.et al.: "Inflammatry cells in the pseudo capsule osteosarcoma" Clinical Orthopaedics and Related Resarch. 300. 225-252 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 須田昭男 他: "骨軟部腫瘍に対する^<201>Tl-chlorideシンチグラフィーの有用性" 日本整形外科学会雑誌. 67. S1117 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 小山内俊久 他: "線維増生著明な悪性顆粒細胞腫の一例" 日本整形外科学会雑誌. 67. S1003 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 石川朗 他: "大腿骨悪性腫瘍に対する人工膝関節置換症例のCy bex IIによる筋力評価" 日本整形外科学会雑誌. 67. S1053 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 加藤博文 他: "頭蓋内.軟部組織.腸管への転移を生じた悪性線維性組織球腫の一例と治療にともなうPCNA発明率の変動" 日本整形外科学会雑誌. 67. S1138 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 渡辺 好博 他: "筋肉内血管腫のMRIと病理組織の比較検討" 日本整形外科学会雑誌. 66(6). S1007- (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 須田 昭男 他: "腫瘍に適応された人工関節の治療成績" 日本整形外科学会雑誌. 66(6). S970- (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 三浦 由太 他: "骨肉腫偽被膜形成と予後" 日本整形外科学会雑誌. 66(6). S1001- (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 佐藤 隆司 他: "骨肉腫の腫瘍組織におけるエストロゲン制御蛋白Ca the psin Dの免疫組織化学的検討" 日本整形外科学会雑誌. 66(6). S1046- (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 須田 昭男 他: "骨肉腫に対する術前動注化学療法の効果判定" 日本整形外科学会雑誌. 65(6). S838 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 三浦 由太 他: "骨肉腫僞被膜形成についての炎症細胞の関与" 日本整形外科学会雑誌. 65(6). S899 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 小山内 俊久 他: "マウス悪性線維性組織球腫実験モデルー構成細胞の形態および核DNA量の検討ー" 日本整形外科学会雑誌. 65(7). S1358 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 高木 理彰 他: "悪性線維性組織球腫(MFH)における細胞外マトリックスとマトリックス受容体についての免疫組織化学的検討" 日本整形外科学会雑誌. 65(7). S1252 (1991)

    • Related Report
      1991 Annual Research Report

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Published: 1991-04-01   Modified: 2016-04-21  

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