| Project/Area Number |
03670886
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
Conservative dentistry
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| Research Institution | TOHOKU UNIVERSITY |
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Principal Investigator |
SASANO Takashi TOHOKU UNIVERSITY LECTURER, 歯学部附属病院, 講師 (10125560)
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| Co-Investigator(Kenkyū-buntansha) |
KURIWADA Shizuko TOHOKU UNIVERSITY ASSISTANT, 歯学部付属病院, 助手 (60225274)
SANJO Daisuke TOHOKU UNIVERSITY PROFESSOR, 歯学部付属病院, 教授 (70013943)
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| Project Period (FY) |
1991 – 1992
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| Project Status |
Completed (Fiscal Year 1992)
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| Budget Amount *help |
¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 1992: ¥200,000 (Direct Cost: ¥200,000)
Fiscal Year 1991: ¥700,000 (Direct Cost: ¥700,000)
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| Keywords | Pulpal blood flow / Periodontal ligament blood flow / Laser Doppler velocimetry / ヒスタミン / レ-ザ-ドプラ-血流計 / 歯髄の血流 / 軸索反射 / 逆伝導性血管拡張 |
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| Research Abstract |
In order to study the interrelationship between the dental pulp and the periodontal tissues, acute response of the periodontal ligament (PL) blood flow to an application of histamine solution to the dental pulp and the gingival sulcus was investigated using laser Doppler velocimetry. The results were as follows:
1. When histamine solution was directly applied to PL, PL blood flow increased immediately after its application. This increase disappeared after washing out the histamine.
2. PL blood flow also increased after applying the histamine solution to the exposed pulp surface and the gingival sulcus, respectively. These increases did not disappear after washing out the histamine in the applied area.
These results indicate that a measurement of tissue blood flow following an application of histamine solution as a tracer is methodologically useful to evaluate an inflammation spread between the tissues.
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