| Project/Area Number |
03670976
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
小児・社会系歯学
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| Research Institution | Nagasaki University |
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Principal Investigator |
SUZUKI Hiroyuki Nagasaki Univ. School of Dentistry, Associated Professor, 歯学部, 助教授 (70018753)
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| Co-Investigator(Kenkyū-buntansha) |
CHIKUBA Satoshi Nagasaki Univ.School of Dentistry, Assistant Professor, 歯学部, 助手 (50244075)
TANAKA Ryuichi Nagasaki Univ.School of Dentistry, Assistant Professor, 歯学部, 助手 (10188352)
村上 久夫 長崎大学, 歯学部・歯科矯正学講座, 助手 (30200273)
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| Project Period (FY) |
1991 – 1992
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| Project Status |
Completed (Fiscal Year 1992)
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| Budget Amount *help |
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1992: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 1991: ¥1,700,000 (Direct Cost: ¥1,700,000)
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| Keywords | Bone Remodeling / Hypergravity / 3-D F.E.M / Bone Morphometry / Orthodontic Force / 骨形態計測 / モルフォメトリ- / リモデリング / 顎骨 / 応力 / 有限要素法 |
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| Research Abstract |
To understand the law of bone remodeling requires precise knowledge of the internal architecture of normal bone, based on the mathematical (Finite Element Method) significance of this architecture as described by the F.E.M. The architecture of normal bone thus must be explained. This study was performed to determine the relationship between stress distribution induced by orthodontic force and alteration of internal remodeling in man-dibular bone. Young adult mongrel dogs of unknown age were used as experimental animals. Twice pulse labels of tetracycline and calcein were performed to obtain histomorphometric parameters of cortical bones prior and posterior to tooth movement. With the use of microscopic plotting tool and minicomputer,the direction of remodeling was reconstracted three-dimensionally. To make a comparison with the alteration of histomorphometric parameters and direction of remodeling units, the principal stress distribution of mandibular bone caused by orthodontic force was obtained by means of 3-D FINITE ELEMENT METHOD. It can be speculated that, as a primary reaction of bone against stress, the optimum microscopic structural change took place in areas of bone which bore tention or pressure due to excess stress, at the same time the internal remodeling of bone was accelerated by increase of activation frequency,accompanied with no increase of remodeling periods.
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