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General Studies on Special Cancer Research

Research Project

Project/Area Number 04042019
Research Category

Grant-in-Aid for international Scientific Research

Allocation TypeSingle-year Grants
SectionSpecial Cancer Research
Research InstitutionAichi Cancer Center Research Institute

Principal Investigator

TOMINAGA Suketami  Aichi Cancer Center Research Institute, 研究所, 所長 (30124530)

Co-Investigator(Kenkyū-buntansha) SASAKI Ryuichiro  Aichi Medical University, Department of Public Health, 公衆衛生学教室, 教授 (80131241)
SHIMIZU Hiroyuki  Gifu University, School of Medicine, Department of Public Health, 医学部・公衆衛生学教室, 教授 (90073139)
YOSHIMURA Takesumi  Institute of Industrial Ecological Science University of Occupational and Enviro, 生態科学研究所, 所長 (20037435)
OHNO Yoshiyuki  Nagoya University, School of Medicine, Department of Preventive Medicine, 医学部・予防医学教室, 教授 (10160590)
YAMAGUCHI Nobuo  Institute of Medical Science, University of Tokyo, 医科学研究所・癌ウイルス研究部, 教授 (90012723)
FUJIKI Hirota  Saitama Cancer Center, Research Institute, 研究所, 副所長 (60124426)
TOYOSIMA Kumao  Center for Adult Diseases, Osaka, 総長 (90029760)
TAKAYAMA Shozo  Showa University, School of Medicine, 医学部, 客員教授 (00085630)
KUROKI Toshio  Institute of Medical Science, University of Tokyo, 医科学研究所・癌細胞研究部, 教授 (90006073)
KITAGAWA Tomoyuki  The Cancer Institute, 癌研究所, 所長 (50085619)
Project Period (FY) 1992 – 1993
Project Status Completed (Fiscal Year 1993)
Budget Amount *help
¥10,000,000 (Direct Cost: ¥10,000,000)
Fiscal Year 1993: ¥5,000,000 (Direct Cost: ¥5,000,000)
Fiscal Year 1992: ¥5,000,000 (Direct Cost: ¥5,000,000)
KeywordsCancer / Epidemiology / Etiology / China / Guatemala / Costa Rica / Columbia / 疫学
Research Abstract

This study group has been functioning as a steering committee of the Special Cancer Research. The major activities of this group were as follows :
1) To conduct pilot studies on cancer research in both developed and developing countries and to evaluate the feasibility and prospects of future studies on cancer. In fiscal year 1992-93, three pilot studies have been conducted in China, Guatemala, Costa Rica and Columbia on cancers of the lung, liver and stomach. Two of the three pilot studies were regarded as feasible and fruitful.
2) To select and propose priority studies on cancer considering the results of the pilot studies. Ten priority studies were selected and proposed in fiscal year 1992-93.
3) To hold meetings of chief investigators to report major results of the studies and to discuss problems in conducting international collaborative studies on cancer. The meeting was held once each year at the end of the fiscal year.
4) To hold symposia to report major results of selected studies. The symposium was held once each year in conjunction with the meeting of chief researchers.
5) To distribute information on special cancer research through news letters to all related investigators. The news letter was published three times a year.

Report

(2 results)
  • 1993 Final Research Report Summary
  • 1992 Annual Research Report
  • Research Products

    (67 results)

All Other

All Publications (67 results)

  • [Publications] Tominaga,S.: "Trends in cancer mortality,incidence and survival in Japan" Jpn.J.Cancer Cehmother.19. 1113-1120 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Tominaga,S.et al.: "Prediction of future cancer mortality in Japan" Jpn.J.Clin.Oncol.22. 365-369 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Tominaga,S.et al.: "Atrophic gastritis and stomach cancer risk:cross-sectional analyses" Jpn.J.Cancer Res.83. 1041-1046 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Tominaga,S.et al.: "A prospective stydy of atrophic gastritis and stomach cancer risk" Jpn.J.Cancer Res.83. 1137-1142 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Tominaga,S.et al.: "Case-control study of bowel habits and colorectal adenoma and cancer" Journal of Epidemiol.3. 1-5 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Yanagisawa,A.: "Frequent c-Ki-ras oncogene activation in mucous cell hyperplasius of pancreas suffering from chronic inflammation." Cancer Res.53. 953-956 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Ishikawa,Y.et al.: "Systemic deposits of Thorium in thorotrast patients with particular reference to sites of minov storage." Radiation Res.135. 244-248 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Kuroki,T.: "Why are human cells resistant to malignant cell transformation in vitro?" Jpn.J.Cancer Res.84. 1091-1100 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Takeuchi,M.et al.: "Functional and physical interaction of protein-tyrosine kinases Fyn and Csk in the signalling system" J.Biol.Chem.268. 27413-27419 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Yamamoto,T.et al.: "Association of Src-family kinase Lyn with B-cell antigen receptor" Immunological Rev.132. 187-206 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Quinn,R.J.et al.: "The consesrved acid binding domain model of inhibitors of protein phosphatases 1 and 2A:Molecular modelling aspects" BioMed.Chem.Let.6. 1029-1034 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Shiio,Y.et al.: "Identification of a DNA element that can enhance p53-mediated transactivation" Oncogene. 8. 2059-2065 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Tamakoshi,A.et al.: "Serum cholesterol and cancer mortality in Japanese civil service workers:Finding from a nested case control study" Journal of Epidemiol.3. 99-107 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Ono,Y.: "Aging population and changing disease pattern in Japan" Proceeding of The First International Symposium of Japan-Russia Medical Exchange Foundation. 86-88 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 吉村健清: "もう一つの大久野島-旧毒ガス弾製造工場従事者の慢性気管支炎有疾率-" 医学のあゆみ. 168(印刷中). (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 川上憲人 他: "わが国と欧米における白血病の発生動向の差異" Medicina. 30. 584-588 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 清水弘之: "前立腺がんの疫学的特徴" 病理と臨床. 11. 654-656 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 佐々木隆一郎: "本邦臨床統計集(下巻)XI.腫瘍 肺癌" 日本臨床. 51. 679-687 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 富永祐民 他: "がん統計白書-罹患/死亡/予後-1993" 篠原出版, 276 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 富永祐民 他: "Cancer Mortality and Morbidity Statistics Japan and the World=1994" Japan Scientific Societies Press CRC Press, 230 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 豊島久真男(編,著): "癌解明への新しいアプローチ" 最新医学社,

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Fujiki,H.et al.: "Significant marine natural products in cancer research" Gazzetta Chimica Italiana, 309-316 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 吉村健清 他: "内科学書,内科学総論「臨床と疫学」の項" 中山書店(印刷中), (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Tominaga,S.: "Trends in cancer mortality, incidence and survival in Japan." Jpn. J. Cancer Chemother.19. 1113-1120 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Tominaga,S. et al.: "Prediction of future cancer mortality in Japan." Jpn.J.Clin.Oncol.22. 365-369 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Tominaga,S. et al.: "Atrophic gastritis and stomach cancer risk : cross-sectional analyses." Jpn. J. Cancer Res.83. 1041-1046 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Tominaga,S. et al.: "A prosective study of atrophic gastritis and stomach cancer risk." Jpn. J. Cancer Res.83. 1137-1142 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Tominaga,S. et al.: "Case-control study of bowel habits and colorectal adenoma and cancer." Journal of Epidemiol.3. 1-5 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Yanagisawa,A et al.: "Frequent c-Ki-ras oncogene activation in mucous cell hyperplasius of pancreas suffering from chronic inflammation." Cancer. Res.53. 953-956 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Ishikawa,Y. et al.: "Systemic deposits of Thorium in thorotrast patients with particular reference to sites of minov storage." Radiation Res.135. 244-243 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Kuroki,T.: "Why are human cells resistant to malignant cell transformation in vitro?" Jpn. J. Cancer Res.84. 1091-1100 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Takeuchi,M. et al.: "Functional and physical interaction of protein-tyrosine kinase Fyn and Csk in the signaling system." J.Biol.Chem.268. 27413-27419 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Yamamoto,T. et al.: "Association of Src-family kinase Lyn with B-cell antigen receptor." Immunological Rev.132. 187-206 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Quinn,R.J. et al.: "The conversed acid binding domain model of inhibitors of protein phosphateses 1 and 2A : Molecular modeling aspects." BioMed. Chem. Let.6. 1029-1034 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Shiio,Y. et al.: "Identification of a DNA element that can enhance p53-mediated transactivation." Oncogen. 8. 2059-2065 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Tamakoshi,A. et al.: "Serum cholesterol and cancer mortality in Japanese civil service workers : Finding from a nested case control study." Journal of Epidemiol.3. 99-107 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Ono,Y.: "Aging population and changing disease pattern in Japan." Proceeding of the First International Symosium of Japan-Russia Medical Exchange Foundation. 86-88 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Tominaga,S. et al.: Japan Scientific Societies Press CRC Press. Cancer mortality and Morbidity Statistics Japan and the World=1994, 1-230 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Fujiki,H. et al.: Gazzetta Chimica Italiana. Significant marine natural products in cancer research, 309-316 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 富永 祐民: "A prospective study of stomach cancer among a rural Japanese population:A 6 year survey" Jpn.J.Cancer Res.83. 568-575 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 富永 祐民: "Atrophic gastritis and stomach cancer risk:cross-sectional analyses" Jpn.J.Cancer Res.83. 1041-1046 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 富永 祐民: "A prospective study of atrophic gastritis and stomach cancer risk" Jpn.J.Cancer Res.83. 1137-1142 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 富永 祐民: "The role of socioeconomic factors in the survival of patients with gastrointestinal cancers" Jpn.J.Clin.Oncol.22. 270-277 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 富永 祐民: "The risk and predictive factors for developing liver cancer among patients with decompensated liver cirrhosis" Jpn.J.Clin.Oncol.22. 278-285 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 北川 知行: "Clonal growth of hepatitis B virus-induced hepatocytes in cirrhotic liver nodules" Cancer Res.52. 6810-6814 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 北川 知行: "Frequent spontaneous sister chromatid exchange in hepatocytes of transgenic mice harboringthe SV40-T antigen" J.Cancer Res.Clin.Oncol.118. 601-605 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 北川 知行: "Alletotype of non-small cell lung carcinoma" Cancer Res.52. 2478-2481 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 黒木 登志夫: "Predominant expression of nPKC a Ca^<2+>-independent isoform of protein kinase C in association with epithelial differentiation" Cell Growth and Differentiation. 4. IN PRESS (1993)

    • Related Report
      1992 Annual Research Report
  • [Publications] 黒木 登志夫: "Rapid phosphorylation of 28-kDa heat shock protein by treatment with okadaic acid and phorbol ester of BALB/MK-2 mouse keratinocytes" Eur.J.Biochem.IN PRESS (1993)

    • Related Report
      1992 Annual Research Report
  • [Publications] 豊島 久真男: "Phosphorylation of the retinoblastoma protein by cdk2" Proc.Natl Acad.Sci.U.S.A.89. 7900-7904 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 豊島 久真男: "Purification and characterization of a possible protooncogene fyn product,p59fyn,from a rat brain particulate fraction" J.Biochem.112. 729-732 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 豊島 久真男: "Oncogenic activation of murine mos protein kinase by DNA rearrengement of its N-terminal coding region" Oncogene. 7. 331-338 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 藤木 博太: "An alternative computer model of the 3-dimensional structures of microcystin-LR and nodularin rationalisting their interactions with protein phosphateses 1 and 2A" BioMed.Chem Lett.2. 299-302 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 藤木 博太: "The role of arginine in interactions of microcystins with protein phosphatases 1 and 2A" BioMed.Chem Lett.4. IN PRESS (1993)

    • Related Report
      1992 Annual Research Report
  • [Publications] 山口 宣生: "Negative regulation of Rb expression by the p53 gene product" Proc.Natl.Acad.Sci.U.S.A.89. 5206-5210 (1993)

    • Related Report
      1992 Annual Research Report
  • [Publications] 山口 宣生: "Delection analysis of a replication origin of human cytomegarovirus by a novel assay system with a combination of microinjection and polymorase chain reaction" Virology. 192. 332-335 (1993)

    • Related Report
      1992 Annual Research Report
  • [Publications] 吉村 健清: "A method for the estimation of completeness of cancer registration-Application to the Fukuoka cancer registry-" Journal of Epidemiology. 2. 7-12 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 吉村 健清: "Human T cell leukemia virus type 1 antibody in patients on chronic hemodialysis in Fukuoka,Japan" Journal of Epidemiology. 2. 21-25 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 清水 弘之: "5-alpha-reductase activity and risk of prostate cancer among Japanese and US wthie and black males" Lancet. 339. 887-889 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 佐々木 隆一郎: "Cohort study on association of malignant neoplasms among the pulmonary tuberculosis patients in Nagoya TB registry" BioMed.Chem Lett.2. 89-95 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 佐々木 隆一郎: "βカロチンと成人病" Proc.Natl.Acad.Sci.U.S.A.3567. 130-131 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 森永 謙二: "アスベストの健康障害" 日本医師会雑誌. 108. 1869-1874 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 原田 健一: "Separation and identification of microcystins in cyanobacteria by frit-fast atom bombardment liquid chromatography/mass spoetromctry" Toxicon. 30. 227-237 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 原田 健一: "Relase of heptapeptide toxin(microcystin)during the decomposition process of microcystis aerusinosa" Toxicon. 1. 48-53 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 原田 健一: "Characerization and toxicity of the glutathione and cysteine conjugates of toxic heptapeptide microcystins" Chem.Res.Toxicol.5. 591-596 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 佐々木 隆一郎: "最新内科学大系19号白血病の疫学" 中山書店, 27-37 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 森永 謙二: "環境百科-アスベスト" 駿河台出版, 152-153 (1992)

    • Related Report
      1992 Annual Research Report

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Published: 1992-04-01   Modified: 2016-04-21  

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