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Defense mechanism of insect (Sarcophaga peregrina)

Research Project

Project/Area Number 04102006
Research Category

Grant-in-Aid for Specially Promoted Research

Allocation TypeSingle-year Grants
Research InstitutionUniversity of Tokyo

Principal Investigator

NATORI Shunji  Tokyo Univ.Pharmaceutical Sci.Prof., 薬学部, 教授 (50012662)

Co-Investigator(Kenkyū-buntansha) KURATA S  Tokyo Univ.Pharmaceutical Sci.Assistant Prof., 薬学部, 助手 (90221944)
KUBO T  Tokyo Univ.Pharmaceutical Sci.Lecturer, 薬学部, 講師 (10201469)
Project Period (FY) 1992 – 1994
Project Status Completed (Fiscal Year 1994)
Budget Amount *help
¥175,000,000 (Direct Cost: ¥175,000,000)
Fiscal Year 1994: ¥50,000,000 (Direct Cost: ¥50,000,000)
Fiscal Year 1993: ¥55,000,000 (Direct Cost: ¥55,000,000)
Fiscal Year 1992: ¥70,000,000 (Direct Cost: ¥70,000,000)
KeywordsSarcophaga / Defense system / Development / Antibacterial protein / Sapecin / Imaginal disc / Ptassium channel / Proteinase / 個体発生 / カリウムチンネル / プロテア-ゼ / 転写因子 / Sarcophagaレクチン / レクチンリセプター
Research Abstract

Insect have developed a unique defense system against various outside stimuli such as microbial infection and integmental injury. We have been studying various defense proteins of Sarcophaga peregrina (the flesh fly). These proteins include a lectin and several antibacterial proteins. Throughout these studies, we came to the conclusion that there are two important novel aspects of these defense proteins. One is that a single defense protein probably plays at least two roles in defense and development. Insects probably have the flexibility to use one defense protein in multiple ways. The other interesting aspect is the phylogenetical significance of the insect defense system. Insect defense system is possibly a prototype of the mammalian defense system. Except these two important aspects, we obtained various important findings on insect immnity. Most of these findings have been published.

Report

(4 results)
  • 1994 Annual Research Report   Final Research Report Summary
  • 1993 Annual Research Report
  • 1992 Annual Research Report
  • Research Products

    (95 results)

All Other

All Publications (95 results)

  • [Publications] So Young Leee: "purification and molecular cloning of CNA an inducible antibacterial protein of leavae of a coleopteran insect、Holotrichia diomphalia" J.Biochem.115. 82-86 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Qhiong Xu: "cloning and identification of testis-specific transcription elongation factor s-II" J.Biol.Chem.269. 3100-3103 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Masafumi Shimoda: "Inhibition of the Ca^<2+>-activated K^+-channel by sapecin B、an insect antibacterial protein" FEBS Letts.339. 59-62 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Katsushige Yamada: "Characterization of the antibacterial peptide derived from sapecin B、anantibacterial protein of Sarcophaga peregrina(flesh fly)" Biochem.J.298. 623-628 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Mayumi Matsui: "purification and characterization of ATBP、a novel protein that binds to A/T stretches in three segments of sarcophaga lectin gene" Eur.J.Biochem.219. 449-454 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Sumio Ohtsuki: "A prolyl endopeptidase of Sarcophaga peregrina(flesh fly):Its purification and suggestion for its participation in the differentiation of the imaginal disc" J.Biochem.115. 449-453 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Shunji Natori: "Antimicrobial peptides" John Wiley & Sons, 283 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Shunji Natori: "phylogenetic perspectives in Immunity: Insect Host Defense" R.G.Landes Company, 197 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Tanji, T.Mizushima, S.Natori and K.Sekimizu: "Induction by psychotropic drugs and local anesthetics of DnaK and GroEL proteins in Escherichia coli" Biochim.Biophys.Acta. 1129. 172-176 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] T.Jomori and S.Natori: "Function of the lipopolysaccharide-binding protein of Periplaneta americana as an apsonin" FEBS Letts.296. 283-286 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.Kurata, H.Saito and S.Natori: "Purification of a 29-kDa hemocyte proteinase of Sarcophaga peregrina." Eur.J.Biochem.204. 911-914 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] H.Komano, T.Kurama, Y.Nagasawa and S.Natori: "Evidence for an increase in positive surface charge and an increase in susceptibility to trypsin of Sarcophaga lectin (from the flesh fly, Sarcophaga peregrina) on its interaction with galactose, a hapten sugar of the lectin." Biochem.J.284. 227-230 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] T.Nakanishi, A.Nakano, K.Nomura, K.Sekimizu and S.Natori: "Purification, gene cloning, and gene disruption of the transcription elongation factor S-II in Saccharomyces cerevisiae." J.Biol.Chem.267. 13200-13204 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] T.Mizushima, S.Natori and K.Sekimizu: "Inhibition of Escherichia coli DNA topoisomerase I activity by phospholipids." Biochem.J.285. 503-506 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.Kurata, H.Saito and S.Natori: "The 29-kDa hemocyte proteinase dissociates fat body at metamorphosis of Sarcophaga." Develop.Biol.153. 115-121 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] M.Ishikawa, T.Kubo and S.Natori: "Purification and characterization of a diptericin homologue from Sarcophaga peregrina (flesh fly)." Biochem.J.287. 573-578 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] A.Nomura, K.Kawasaki, T.Kubo and S.Natori: "Purification and localization of p10, a novel protein that increases in nymphal regenerating legs of Periplaneta americana (American cockroach)." Int.J.Dev.Biol.36. 391-398 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] H.Hirai, S.Natori and K.Sekimizu: "Reversal by phosphatidylglycerol and cardiolpin of inhibition of transcription and replication by histones in vitro." Arch.Biochem.Biophys.298. 458-463 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Homma, K.Matsuyama, H.Komano and S.Natori: "The fate of the prosegment in the acute-phase and programd synthesis of sapecin, and antibacterial peptide of the flesh fly (Sarcophaga peregrina)." Biochem.J.288. 281-284 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] H.Saito, S.Kurata and S.Natori: "Purification and characterization of a hemocyte proteinase of Sarcophaga, possibly participating in elimination of foreign substances." Eur.J.Biochem.209. 939-944 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Tanji, Y.Ohta, S.Kawato, T.Mizushima, S.Natori and K.Sekimizu: "Decrease by physchotropic drugs and local anaesthetics of membrane fluidity measured by fluorescence anisotropy in Escherichia coli." J.Pharm.Pharmcol.44. 1036-1037 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Yamada and S.Natori: "Purification, sequence and antibacterial activity of two novel sapecin homologues from Sarcophaga embryonic cells : similarity of sapecin B to charybdotoxin." Biochem.J.291. 275-279 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] T.Kubo, K.Kawasaki and S.Natori: "Transient appearance and localizaion of a 26-kDa lectin, a novel member of the Periplaneta lectin family, in regenerating cockroack leg." Devel.Biol.156. 381-390 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.Haq, S.Natori and K.Sekimizu: "Heat-induced DNA relaxation in vitro by mouse DNA topoisomerase I in the presence of ethidium bromide." J.Biochem.113. 620-624 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] H.Hirai, S.Takeda, S.Natori and K.Sekimizu: "Inhibition of SV40 DNA replication in vitro by chlorpromazine." Biol.Pharm.Bull.16. 565-567 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Y.Nagasawa, S.Kurata, H.Komano and S.Natori: "Purification and heterogeneous localizaion of Sarcophaga lectin receptor on the surface of imaginal discs of Sarcophaga peregrina (flesh fly)." Develop.Growth & Differ.35. 331-340 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] R.Iijima, S.Kurata and S.Natori: "Purification, characterization, and cDNA cloning of an antifungal protein from the hemolymph of Sarcophaga peregrina (flesh fly)." J.Biol.Chem.268. 12055-12061 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] N.Adachi, T.Kubo and S.Natori: "Purification and characterization of the arylphorin gene specific binding protein from an embryonic cell line of Sarcophaga peregrina (flesh fly)." J.Biochem.114. 55-60 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] T.Mizushima, S.Natori and K.Sekimizu: "Relaxation of supercoiled DNA associated with induction of heat shock proteins in Escherichia coli." Mol.Gen.Genet.238. 1-5 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] A.Kobayashi, M.Matsui, T.Kubo and S.Natori: "Purification and characterization of a 59-kilodalton protein that specifically binds to NF-kB-binding motifs of the defense protein genes of Sarcophaga peregrina (the flesh fly)." Mol.Cell.Biol.13. 4049-4056 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] R.Nanbu, T.Kubo, T.Hashimoto and S.Natori: "Purification of an AU-rich RNA binding protein from Sarcophaga peregrina (flesh fly) and its identification as a thiolase." J.Biochem.114. 432-437 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Kawasaki, T.Kubo and S.Natori: "A novel role of Periplaneta lectin as an opsonin to recognize 2-keto-3-deoxy ocutonate residues of bacterial lipopolysaccharides." Comp.Biochem.Physiol.106B. 675-680 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] N.Takahashi, S.Kurata and S.Natori: "Molecular cloning of cDNA for the 29kDa proteinase participating in decomposition of the larval fat body during metamorphosis of Sarcophaga peregrina (flesh fly)." FEBS Letts.334. 153-157 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.Takeda, Y.Sagara, K.Kita, S.Natori and K.Sekimizu: "Purification of a GTP-binding protein localized in mitochondria." J.Biochem.114. 684-690 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] H.Iwai, Y.Nakajima, S.Natori, Y.Arata and I.Shimada: "Solution conformation of an antibacterial peptide, sarcotoxin IA,as determined by ^1H-NMR." Eur.J.Biochem.217. 639-644 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.Y.Lee, H.J.Moon, S.Kurata, T.Kurama, S.Natori and B.L.Lee: "Purification and molecular cloning of cDNA for an inducible antibacterial protein of larvae of a coleopteran insect" Holotrichia diomphalia.J.Biochem.115. 82-86 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Q.Xu, T.Nakanishi, K.Sekimizu and S.Natori: "Cloning and identification of testis-specific transcription elongation factor S-II." J.Biol.Chem.269. 3100-3103 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] M.Shimoda, H.Takagi, S.Kurata, T.Yoshioka and S.Natori: "Inhibition of the Ca^<2+> -activated K^+ -channel by sapecin B,an insect antibacterial protein." FEBS Letts.339. 59-62 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Yamada and S.Natori: "Characterization of the antimicrobial peptide derived from sapecin B,an antibacterial protein of Sarcophaga peregrina (flesh fly)." Biochem.J.298. 623-628 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] M.Matsui, A.Kobayashi, T.Kubo and S.Natori: "Purification and characterization of ATBP,a novel protein that binds to A/T stretches in three segments of the Sarcophaga lectin gene." Eur.J.Biochem.219. 449-454 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.Ohtsuki, K.Homma, S.Kurata, H.Komano and S.Natori: "A prolyl endopeptidase of Sarcophaga peregrina (flesh fly) : Its purification and suggestion for its participation in the differentiation of the imaginal discs." J.Biochem.115. 449-453 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] R.Chalk, H.Townson, S.Natori, H.Desmond and P.Ham: "Purification of an insect defensin from the mosquito, Ades aegypti.Insect Biochem." Molec.Biol.24. 403-410 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] M.Masutani, T.Nozaki, Y.Hitomi, M.Ikejima, K.Nagasaki, A.C.De Prati, S.Kurata, S.Natori, T.Sugimura and H.Esumi: "Cloning and functional expression of poly (ADP-ribose) polymerase cDNA from Sarcophaga peregrina." Eur.J.Biochem.220. 607-614 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] J.I.Kim, H.Iwai, S.Kurata, M.Takahashi, K.Masuda, I.Shimada, S.Natori, Y.Arata and K.Sato: "Synthesis and characterization of sapecin and sapecin B." FEBS Letts.342. 189-192 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] H.Okuyama, S.Kurata and S.Natori: "Selective cessaion of protein synthesis in adipocytes produced by dissociating Sarcophaga larval fat body with chymotrypsin." Insect Biochem.Molec.Biol.24. 525-530 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Homma, S.Kurata and S.Natori: "Purification, characterization, and cDNA cloning of procathepsin L from the culture medium of NIH-Sape-4, an embryonic cell line of Sarcophaga peregrina (flesh fly), and its involvement in the differentiation of imaginal discs." J.Biol.Chem.269. 15258-15264 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] H.J.Moon, S.Y.Lee, S.Kurata, S.Natori and B.L.Lee: "Purification and molecular cloning of cDNA for an inducible antibacterial protein from larvae of the coleopteran, Tenebrio molitor." J.Biochem.116. 53-58 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] J.A.-Bravo, S.Kurata and S.Natori: "Novel synthetic antimicrobial peptides effective against methicillin-resistant Staphylococcus aureus." Biochem.J.302. 535-538 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] H.Sugiyama and S.: "Induction of glutathione metabolism in the fat body of Sarcophaga peregrina by integumental injury." J.Biochem.116. 1171-1175 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] So Young Leee: "Purification and molecular of CDNA for an inducible antibacterial protein of larvae of a coleopteran insect,Holotrichia diomphalia" J.Biochem.115. 82-86 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Qhiong Xu: "Cloning sand identification of testis-specific transcription elonqation factor S-II" J.Biol.Chem.269. 3100-3103 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Masafumi Shimoda: "Inhibition of the Ca^<2+>-antivated K^+-channel by sapecin B, an insect antibacterial protein" FEBS Letts.339. 59-62 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Katsushige. Yamada: "Characterization of the antibacterial peptide derived from sapecin B,an antibacterial protein of Sarcophaga pereqrina (flesh fly)" Biochem.J.298. 623-628 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Mayumi Matsui: "Purification and characterization of ATBP, a novel protein that bind to A/T stretches in three seqments of Sarcophaqa Iectin qene" Eur.J.Biochem.115. 449-454 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Sumio Ohtsuki: "Aprolyl endopeptidase of Sarcophaqa pereqrina(flesh fly);Its purification and suqqestion for its participation in the differentiation of the imaginal di" J.Biochem. 115. 449-453 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Chalk R: "Purification of an insect defensin from the mosquito, Ades aeqypti" Insect Biochem. Mol. Biol.24. 403-410 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Mitsuko Masutani: "Cloning and functional expression of (ADP-ribose)polymerase cDNA from Sarcophaga Pereqrina" Eur.J.Biochem.220. 607-614 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Jae I1 Kim: "Synthesis and characterization of sapecin snd sapecin B" FEBS Letts.342. 189-192 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Hajime Okuyama: "Selective cessation of protein synthesis in adipocytes produced by dissociating Sarcophaga larval fat body with chymotrypsin" Insect.Biochem.Mol.Biol.24. 525-530 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] KOichi Homma: "Purification,characterization,and cDNA cloning of procathepsin L from the culture medium of NIH-Sape-4,and embryonic cell line of Sarcophaqa pereqrina" J.Biol.Chem.269. 15258-15264 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Hyun Joo Moon: "Purification and molecular cloning of cDNA for an inducible antibacterial protein from larvas of the coleopteran,Tenebrio molitor" J.Biochem.302. 53-58 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Juan Alvarcz-Bravo: "Novel synthetic antimicrobial effective against methicillin-resistant Staphylococcus aureus" Biochem J.302. 535-538 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Hiromi Sugiyama: "Induction of qlutathione in the fat body of Sarcophaqa pereqrina by integumental injury" J.Biochem.116. 1171-1175 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Shunji Natori: "Antimicrobial peptides" John wiley &Sons, 283 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Shunji Natori: "Phylogenetic Perspectives in Immunity:Insect Host Defense" R.G.Landes Company, 197 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Katsushige Yamada: "Purification,sequence and antibacterial activityof two novel sapecin homologues from Sarcophaga embryonic cells:similarity of sapecin B to charybdotoxin." Biochem.J.291. 275-279 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Takeo Kubo: "Transient appearance and localization of a 26-kDa lectin,a novel member of the Periplaneta lectin family,in regenerating cocroach leg." Devel.Biol.156. 381-390 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Shafiqul Haq: "Heat-induced DNA relaxation in vitro by mouse DNA topoisomerase I in the presence of ethidium bromide." J.Biochem.113. 620-624 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Hiroshi Hirai: "Inhibition of SV 40 DNA replication in vitro by chlorpromazine" Biol.Pharm.Bull.16. 565-567 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Yasuo Nagasawa: "Purification and heterogeneous localization of Sarcophaga lectin receptor on the surface of imaginal discs of Sarcophaga peregrina(flesh fly)." Develop.Growth & Differ.35. 331-340 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Rosuke Iijima: "Purification,characterization,and cDNA cloning of an antifungal protein from the hemolymph of Sarcophaga peregrina(flesh fly)larvae." J.Biol.Chem.268. 12055-12061 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Nobuaki Adachi: "Purification and characterization of the arylphorin gene specific binding protein from an embryonic cell line of Sarcophaga peregrina(flesh fly)." J.Biochem.114. 55-60 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Tohru Mizushima: "Relaxation of supercoiled DNA associated with induction of heat shock proteins in Escherichia coli." Mol.Gen.Genet.238. 1-5 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Ayako Kobayashi: "Purification and characterization of a 59-kilodalton protein that specifically binds to NF-kB-binding motifs of the defense protein genes of Sarcophaga peregrina(flesh fly)." Mol.Cell.Biol.13. 4049-4056 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Rika Nanbu: "Purification of an AU-rich RNA binding protein from Sarcophaga peregrina(flesh fly)and its identification as a thiolase." J.Biochem.114. 432-437 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Kiyoshi Kawasaki: "A novel role of Periplaneta lectin as an opsonin to recoganize 2-keto-3-deoxy ocutonate residues of bacterial lipopolysaccharides." Comp.Biochem.Physiol.106B. 675-680 (1993)

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      1993 Annual Research Report
  • [Publications] Noboru Takahashi: "Molecular cloning of cDNA for the 29 kDa proteinase participating in decomposition of the larval fat body during metamorphosis of Sarcophaga peregrina(flesh fly)." FEBS Lett.334. 153-157 (1993)

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      1993 Annual Research Report
  • [Publications] Shizu Takeda: "Purification of a GTP-binding protein localized in mitochondria." J.Biochem.684. 684-690 (1993)

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      1993 Annual Research Report
  • [Publications] Hideo Iwai: "Solution conformation of an antibacterial peptide,sarcotoxin IA,as determined by ^1H-NMR." Eur.J.Biochem.217. 639-644 (1993)

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  • [Publications] 中西敏行: "新しい二つのS-IIについて-精巣特異的S-IIと酵母S-II-" 実験医学. 11. 55-60 (1993)

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      1993 Annual Research Report
  • [Publications] 名取俊二: "がんに対する生体防御機構 非免疫系抗腫瘍性因子を中心として" 共和書院(今西二郎), 12 (1993)

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      1993 Annual Research Report
  • [Publications] Kayoko Tanji: "Induction by psychotropic drugs and local anesthetics of Dnak and GroEL proteins in Escherichia coli" Biochim.Biophys.Acta. 1129. 172-176 (1992)

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      1992 Annual Research Report
  • [Publications] Takahito Jomori: "Function of the lipopolysaccharide-binding protein of periplaneta americana as an opsonin" FEBS Letts.296. 283-286 (1992)

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      1992 Annual Research Report
  • [Publications] Shoichiro Kurata: "Purification of a 29-kDa hemocyte proteinase of Sarcophaga peregrina" Eur.J.Biochem.204. 911-914 (1992)

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      1992 Annual Research Report
  • [Publications] Hiroto Komano: "Evidence for an increase in positive surface charge and an increase in susceptibility to trypsin of Sarcophaga lectin on its interaction with galactose,a hapten sugar of the lectin" Biochem.J.284. 227-230 (1992)

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      1992 Annual Research Report
  • [Publications] Toshiyuki Nakanishi: "Purification,gene cloning,and gene disruption of the transcription elongation factor S-II in Saccaromyces cerevisiae" J.Biol.Chem.267. 13200-13204 (1992)

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  • [Publications] Tohru Mizushima: "Inhibition of Escherichia coli DNA topoisomerase I activity by phospholipids" Biochem.J.285. 503-506 (1992)

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      1992 Annual Research Report
  • [Publications] Shoichiro Kurata: "The 29-kDa hemocyte proteinase dissociates fat body at metamorphosis of Sarcophaga" Develop.Biol.153. 115-121 (1992)

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      1992 Annual Research Report
  • [Publications] Mami Ishikawa: "Purification and characterization of a diptericin homologue from Sarcophaga peregrina (flesh fly)" Biochem.J.287. 573-578 (1992)

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      1992 Annual Research Report
  • [Publications] Aya Nomura: "Purification and localization of p10,a novel protein that increases in nymphal regenerating legs of Periplaneta americana (American cockroach)" Int.J.Dev.Biol.36. 391-398 (1992)

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      1992 Annual Research Report
  • [Publications] Hiroshi Hirai: "Reversal by phosphatidylglycerol and cardiolipin of inhibition of transcription and replication by histones in vitro" Arch.Bichem.Biophys.298. 458-463 (1992)

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      1992 Annual Research Report
  • [Publications] Ko-ichi Homma: "The fate of the prosegment in the acute-phase and programmed synthesis of sapecin,an antibacterial peptide of the flesh fly(Sarcophaga peregrina)" Biochem.J.288. 281-284 (1992)

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      1992 Annual Research Report
  • [Publications] Hiromi Saito: "Purification an characterization of a hemocyte proteinase of Sarcophaga,possibly participating in elimination of foreign substances" Eur.J.Biochem.209. 939-944 (1992)

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      1992 Annual Research Report
  • [Publications] 名取 俊二: "無脊椎動物の生体防御" 学会出版センター, 14 (1992)

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      1992 Annual Research Report
  • [Publications] 中島 由紀: "無脊椎動物の生体防御" 学会出版センター, 13 (1992)

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      1992 Annual Research Report

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Published: 1992-04-01   Modified: 2016-04-21  

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