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Regulation of gene expression during development

Research Project

Project/Area Number 04304007
Research Category

Grant-in-Aid for Co-operative Research (A)

Allocation TypeSingle-year Grants
Research Field 動物発生・生理学
Research InstitutionHIROSHIMA UNIVERSITY

Principal Investigator

SHIMADA Hiraku  Faculty of Science, Hiroshima University.Professor, 理学部, 教授 (70011559)

Co-Investigator(Kenkyū-buntansha) SUEMITSU Takashi  Fac.Sci., Saitama Univ., Asso.Prof., 理学部, 助教授 (40092019)
SATOH Noriyuki  Fac.Sci., Kyoto Univ., Professor, 理学部, 教授 (30025481)
ABE Shinichi  Fac.Sci., Kumamoto Univ., Professor, 理学部, 教授 (90109637)
YAMAGAMI Kenjiro  Fac.Sci., Sophia Univ.Professor, 理工学部, 教授 (50011474)
KATAGIRI Chiaki  Fac.Sci., Hokkaido Univ., Professor, 理学研究科, 教授 (90000827)
Project Period (FY) 1992 – 1994
Project Status Completed (Fiscal Year 1994)
Budget Amount *help
¥19,000,000 (Direct Cost: ¥19,000,000)
Fiscal Year 1994: ¥4,000,000 (Direct Cost: ¥4,000,000)
Fiscal Year 1993: ¥6,000,000 (Direct Cost: ¥6,000,000)
Fiscal Year 1992: ¥9,000,000 (Direct Cost: ¥9,000,000)
Keywordsgene expression / developmet / amphibia / fish / ascidia / sea urchin / artemia / planaria / 発生 / 遺伝子クローニング / 遺伝子発現調節 / 分化マーカー / 多様性
Research Abstract

A recent remarkable accumulation of information on gene regulation of various events during early development of animals has been obtained through studies using only limitted variety of animal species, such as some species of mammals, amphibians, an insect (Drosophila) and a nematoda (C.elegans). However, for an extensive understanding of molecular processes governing early development, the detailed information on the regulation of gene expression during embryogenesis of a large variety of animals is definitely expected. The present research project has thus been proposed to access the comparative aspect of gene regulation of early development. The following studies were performed in this project. (1) The collagenase gene was cloned from the frog (Rana catesbiana) and its expression in larval skin was studied in relation to metamorphosis. (2) A cDNA,expression of which changes markedly during metamorphosis, was cloned from liver of Xenopus laevis tadpole. (3) A trial to detect sperm-specific genes from spermatogonia of a newt (Triturus pyrrhogaster). (4)Genes for the fish (Oryzias latipes) hatching enzyme were cloned and their expression in prehatching stages was studied. (5) Transcription factors regulating the skeletal muscle actin genes in embryos of a solitary ascidian (Halocynthia roretzi) were studied. (6) LIM-class homeotic genes were cloned from Halocynthia roretzi and pattern of their expression during development was studied. (7) Genes related to budding of a colonial ascidian (Polyandrocarpa misakiensis) were cloned. (8) Regulation of genes for arylsulfatase in the sea urchin (Hemicentrotus pulcherrimus) and for the exogastrula-inducing peptides of the sea urchin (Anthocidaris crassispina) were studied. (8) Cloning of the treharase cDNA was started in relation to crustacian dormancy (Artemia salina). (9) An extensive search for genes related to regulation of planarian (Dugesia japonica) regeneration was started.

Report

(4 results)
  • 1994 Annual Research Report   Final Research Report Summary
  • 1993 Annual Research Report
  • 1992 Annual Research Report
  • Research Products

    (124 results)

All Other

All Publications (124 results)

  • [Publications] H.Orii: "Pou-domain genes in planarian Dugesia japonica: The structure and expression" Biochem.Biophys.Res.Commun.192. 1395-1402 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.Abe: "How is the flagellar length of mature sperm determined? III.Comparison of initial rate of flagella in spermatids from Cynopus and Xenopus in the prsence--." Exp.Cell Res.198. 373-374 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Z.-S.Ji: "Differentiation from spermatogonia to primary spermatocytes by FSH in organ culture of testes fragments from the newt,Cynopus pyrrhogaster." Develop.Growth & Differ.34. 649-660 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.-I.Abe: "Initiation and stimulation of spermatogenesis in vitro by mammaliian FSH in the Japanese newt,Cynopus pyrrhogaster." Int.J.Dev.Biol.38. 201-208 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Z.-S.Ji: "Mammalian FSH stimulates DNA synthesis in secondary spermatoginia and Sertoli cells in organ culture of testes fragments from the newt,Cynopus pyrrhogaster." Zygote. 2. 53-61 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] N.Ariyoshi: "cDNA cloning and expression of Xenopus sperm-specific basic nuclear protein 5 (SP5) gene." Molec.Reprod.Develop.37. 363-369 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] M.Mukai: "Rapid and quantitative detection of aspartic proteinase in animal tissue by radio-labeled pepstatin A." Zool.Sci.11. 221-227 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Oofusa: "Regionally and hormonally regulated expression of collagen and collagenase in the anuran larval skin." Int.J.Dev.Biol.38. 345-350 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] A.Kawai: "A three step mechanism of action of thyroid hormone and mesenchyme in metamorphoric changes in anuran larval skin." Develop.Biol.166. 477-488 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.Yasumasu: "cDNAs and the genes of HCE and LCE,two constituents of the medaka hatching enzyme." Develop.Growth & Differ.36. 241-250 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Murata: "Synchronous production of the low- and high-molecular weight precursors of the egg envelope subunits,in response to estrogen administration in the teleost fish" Gen.Comp.Endocrinol.95. 232-239 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Murata: "Cloning of cDNAs for the precursor protein of a low molecular weight subunit of the inner layer of the egg envelope (chorion) of the fish,Oryzias latipes." Develop.Biol.(in press). (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Yoshizato: "Epidermal cells of the tail of anuran larva have a potency to transform into the adult type cells." Zool.Sci.10. 183-187 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Y.Izutsu: "Metamorphosis-dependent recognition of larval skin as non-self by inbred aduld frogs (Xenopus Laevis)." J.Exp.Zool.266. 163-167 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Y.Izutsu: "Differential distribution of epidermal basal cells in the anuran larval skin correlates with the skin's region-specific fate at metamorphosis." J.Exp.Zool.267. 608-615 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Z.-S.Ji: "Differentiation of primary spermatocytes to elongated spermatids by mammalian FSH in organ culture of testes fragments from the newt,Cynopus pyrrhogaster." Develop.Growth & Differ.36. 445-455 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Z.-S.Ji: "Promotion of differentiation of newt primary spermatocytes into spermatids by mammalian FSH via Sertoli cells." J.Exp.Zool.(in press). (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Maekawa: "Proliferation of newt spermatogonia by mammalian FSH via Sertoli cells in vitro." J.Exp.Zool.(in press). (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] T.Itoh: "Remodeling of human sperm chromatin mediated by nucleoplasmin from amphibian eggs." Develop.Growth & Differ.35. 59-66 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] M.Moriya: "Immuno-electron microscopic localization of calmodulin and calmodulin-binding proteins in the mouse germ cells during spermatogenesis and maturation." Cell Tiss.Res.271. 441-451 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Ohsumi: "Chromosome condensation in Xenopus mitotic extracts without histone Hl." Science. 262. 2033-2035 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Ch.Katagiri: "Remodeling of sperm chromatin induced in egg extracts of amphibians." Int.J.Dev.Biol.38. 209-216 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] A.Kawahara: "Transient expression of a unique gene in liver parenchymal cells during amphibian metamorphosis." Proc.8th Int.Confer.Int.Soc.Differ.194-196 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.Wada: "Spatially and temporally regulated expression pattern of the LIM class hameobox gene Hrlim suggests multiple distinct functions in development of the ascidian,Halocynthia roretzi." Mech.Develop.(in press). (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] I.Araki: "Expression of AMDl,a gene for a MyoDl-related factor in the ascidian Halocynthia roretzi." Roux's Arch.Dev.Biol.203. 320-327 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] T.Kusakabe: "Tunicate muscle actin genes: Structure and organization as a gene cluster." J.Mol.Biol.227. 955-960 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] A.Hikosaka: "Introduction and expression of recombinant genes in ascidian embryos." Develop.Growth & Differ.34. 627-634 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] A.Hikosaka: "Regulated spatial expression of fusion gene constructs with the 5' upstream region of Halocynthia roretzi muscle actin gene in Ciona savignyi embryos." Roux's Arch.Dev.Biol.203. 104-112 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] A.Hikosaka: "Short upstream sequences associated wilth the muscle-specific expression of an actin gene in ascidian embryos." Develop.Biol.166. 763-769 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] T.Kusakabe: "Co-expression and promoter function in two muscle actin gene complexes of different structural organization in the ascidian Halocynthia roretzi." Develop.Biol.(in press). (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Yamada: "Cis-acting elements for proper ontogenic expression of arylsulfatase gene of sea urchin embryo." Develop.Growth & Differ.34. 719-729 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Yamada: "cis-Elements and protein factors related to regulation of transcription of arylsulfatase gene during sea urchin development." Develop.Growth & Differ.35. 703-710 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Akasaka: "Corrected structure of the 5' flanking region of arylsulfatase gene of the sea urchin,Hemicentrotus pulcherrimus.21GC33:Develop.Growth & Differ." 36. 633-636 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] T.Yamamoto: "A long polypyrimidine:polypurine sequence in 5' flanking region of arylsulfatase gene of sea urchin embryo." Int.J.Dev.Biol.38. 337-344 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Y.Iuchi: "Detection and characterization of the cis-element in the first intron of the Ars gene in sea urchin." Develop.Growth & Differ.37(in press). (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Y.Seike: "Purification of sperm-Lectin extracted from spermatozoa of the sea urchin Hemicentrotus pulcherrimus." Develop.Growth & Differ.34. 285-291 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Kinoshita: "Maternal exogastrula-inducing peptides (EGIPs) and their changes during development in the sea urchin,Anthocidaris crassispina." Develop.Growth & Differ.34. 665-672 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] N.Mizuno: "Localization of an exogastrula-inducing peptide (EGIP) in embryos of the sea urchin Anthocidaris crassispina." Develop.Growth & Differ.35. 523-533 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Y.Fujita: "Effects of exogastrula-induching peptides on cell proliferation in embryos of the sea urchin Anthocidaris crassispina." Zool.Sci.10. 793-802 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Y.Chino: "Formation of the adult rudiment of sea urchin is influenced by thyroid hormones." Develop.Biol.161. 1-11 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] H.Kobayashi: "Local change of an exogastrula-inducing peptide (EGIP) in the pluteus larva of the sea urchin A.crassispina." Zool.Sci.11. 157-160 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Y.Fujita: "A protein that binds an exogastrula-inducing peptide,EGIP-D,in the hyaline layer of sea urchin embryo." Develop.Growth & Differ.36. 275-280 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Yamasu: "Molecular cloning of a cDNA that encodes the precursor to several exogastrula-inducing peptides,EGF-related polypeptides of the sea urchin A.crassispina.21GC43:Eur.J.Biochem." (in press). (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.Fujiwara: "Ascidian budding as a transdifferentiation-like system: multipotent epithelium is not undifferentiated." Develop.Growth & Differ.34. 463-472 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.Fujiwara: "A complementary DNA for an ascidian embryonic nuclear antigen Hgv2 encodes a protein closely related to the amphibian histone-binding protein Nl." J.Biochem.113. 189-195 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.Fujiwara: "Temporal and spatial expression of a gene for the nuclear protein Hgv2 in embryos and adults of the ascidian Halocynthia roretzi." Develop.Growth & Differ.35. 221-229 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Kawamura: "Developmental role of endogenous retinoids in the determination of morphallactic field in budding tunicates." Development. 117. 835-845 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Kawamura: "Transdifferentiation of pigmented multipotent epithelium during morphallactic development of budding tunicates." Int.J.Dev.Biol.38. 369-377 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] M.Shimada: "Expression of genes for two C-type lectins during budding of the ascidian Polyandrocarpa misakiensis." Roux's Arch.Dev.Biol.(in press). (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.Yasumasu: "Isolation of cDNAs for LCE and HCE,two constituent proteases of the hatching enzyme of Oryzias latipes,and concurrent expression of their mRNA during development." Develop.Biol.153. 250-258 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Murata: "Isolation of H-SF substances,the high-molecular-weight precursors of egg envelope protein,from the ascites accumulated in the estrogen-treated fish,Oryzias latipes." Zygote. 1. 315-324 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] H.Orii et al.: "Pou-domain genes in planalian Degesia japonica : The structure and expression." Biochem.Biophys.Res.Commun.192. 1395-1402 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] N.Ariyoshi et al: "cDNA cloning and expression of Xenopus sperm-specific basic nuclear protein 5 (sp5) gene." Molec.Reprod.Develop.37. 363-369 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] A.Kawahara et al: "Transient expression of a unique gene in liver parenchymal cells during amphibian metamorphosis." Proc.8th.Int.Confer, Int.Soc.Differ.194-196 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.Wada et al: "Spatially and temporally regulated expression pattern of the LIM class homeobox gene Hrlim suggests multiple distinct functions in development of the ascidian, Halocynthia roretzi." Mech.Develop.(in press). (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] T.Kusakabe et al: "Co-expression and promoter function in two muscle actin gene complexes of different structural organization in the ascidian Halocynthia roretzi." Develop.Biol.(in press). (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Y.Iuchi et al: "Detection and characterization of the cis-element in the first intron of the Ars gene in sea urchin." Develop.Growth & Differ.(in press). (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Yamasu et al: "Molecular cloning of a cDNA that encodes the precursor to several exogastrula-inducing peptides, EGF-related polypeptides of the sea urchin Anthocidaris crassispina." Eur.J.Biochem.(in press). (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] M.Shimada et al: "Expression of genes for two C-type lectins during budding of the ascidian Polyandrocarpa misakiensis." Roux's Arch.Dev.Biol.(in press). (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.Yasumasu et al: "Isolation of cDNAs for LCE and HCE,two constituent proteases of the hatchin enzyme of Oryzias latipes, and concurrent expression of their mRNAs during development." Develop.Biol.153. 250-258 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.Yasumasu et al: "cDNA and genes of HCE and LCE, two constituents of the medaka hatching enzyme." Develop.Growth & Differ.36. 241-250 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Murata et al: "Cloning of cDNAs for the precursor protein of a low molecular weight subunit of the inner layr of the egg envelope (chorion) of the fish Oryzias latipes." Develop.Biol.(in press). (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Oofusa et al: "Regionally and hormonally regulated expression of collagen in the anuran larval skin." Int.J.Dev.Biol.38. 345-350 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] T.Yamamoto et al: "A long polypyrimidine : polypurine sequence in 5' flanking region of arylsulfatase gene of sea urchin embryo." Int.J.Dev.Biol.38. 337-344 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] I.Araki et al: "Expression of AMDl, a gene for a MyoDl-related factor in the ascidian Halocynthia roretzi." Roux's Arch.Dev.Biol.203. 320-327 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] A.Hikosaka et al: "Short upstream sequences associated with the muscle-specific expression an actin gene in ascidian embryos." Develop.Biol. 166. 763-769 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.-I.Abe: "Initiation and stimulation of spermatogenesis in vitro by mammalian follicle-stimulating hormone in the Japanese newt." International Journal of Developmental Biology. 38. 201-208 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Z.-S.Ji: "Mammalian FSH stimulates DNA synthesis in secondary spermatogonia and Sertoli cells in organ culture of testes fragment------." Zygote. 2. 53-61 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] N.Ariyoshi: "cDNA cloning and expression of Xenopus sperm-specific basic nuclear protein 5(SP5)gene." Molec.Reprod.Develop.37. 363-369 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Z.-S.Ji: "Differentiation of primary spermatocytes to elongated spermatids by mammalian FSH in organ culture of testes fragments from the newt,C.pyrrhogaster." Develop.Growth & Differ.36. 445-455 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Z.-S.Ji: "Promotion of differentiation of newt primary spermatocytes into spermatids by mammalian FSH via Sertoli cells." J.Exp.Zool.(in press). (1995)

    • Related Report
      1994 Annual Research Report
  • [Publications] K.Maekawa: "Proliferation of newt spermatogonia by mammalian FSH via Sertoli cells in vitro." J.Exp.Zool.(in press). (1995)

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      1994 Annual Research Report
  • [Publications] K.Kawamura: "Transdifferentiation of pigmented multipotent epithelium during morphallactic development of budding tunicates." Int.J.Dev.Biol.38. 369-377 (1994)

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      1994 Annual Research Report
  • [Publications] M.Shimada: "Expression of genes for two C-type lectins during budding of the ascidian Polyandrocarpa misakiensis." Roux's Arch.Dev.Biol.(in press). (1995)

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      1994 Annual Research Report
  • [Publications] K.Yamagami: "Intrahepatic formation of SF substances,the precursors of egg envelope proteins,in response to estrogen administration in fish." Perspectives in Comparative Endocrinol.316-324 (1994)

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      1994 Annual Research Report
  • [Publications] S.Yasumasu: "cDNAs and genes of HCE and LCE,two constituents of the madaka hatching enzyme." Develop.Growth & Differ.36. 241-250 (1994)

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      1994 Annual Research Report
  • [Publications] K.Murata: "Synchronus production of the low-and high-molecular weight precursors of the egg envelope subunits,in response to----." Gen.Comp.Endocrinol.95. 232-239 (1994)

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      1994 Annual Research Report
  • [Publications] K.Murata: "Cloning of cDNAs for the precursor protein of a low molecular weight subunit of the inner layer of the egg envelope(chorion)of the fish,Oryzias latipes." Develop.Biol.(in press). (1995)

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      1994 Annual Research Report
  • [Publications] CH.Katagiri: "Remodeling of sperm chromatin induced in egg extracts of amphibians." Int.J.Dev.Biol.38. 209-216 (1994)

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      1994 Annual Research Report
  • [Publications] A.Kawahara: "Transient expression of a unique gene in liver parenchymal cells durino amphibian metamorphosis." Proc.8th Int.Confer.Int.Soc.Differ.194-196 (1994)

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      1994 Annual Research Report
  • [Publications] S.Wada: "Spatially and temporally regulated expression pattern of the LIM class homeobox opne Hrlim sugaests multiple distinct functions in development----." Mech.Develop.(in press). (1995)

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      1994 Annual Research Report
  • [Publications] I.Araki: "Expression of AMDl,a gene gor a MyoDl-related factor in the ascidian Halocythia roretzi." Roux's Arch.Dev.Biol.203. 320-327 (1994)

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      1994 Annual Research Report
  • [Publications] A.Hikosaka: "Short upstream sequences associated with the muscle-specific expression of an actin gene in ascidian embryos." Develop.Biol.166. 763-769 (1994)

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      1994 Annual Research Report
  • [Publications] T.Kusakabe Co-expression and promoter fnction in two muscle actin gene complexes of different structural organization in the----.: "Develop.Biol." (in press). 1995.

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      1994 Annual Research Report
  • [Publications] K.Akasaka: "Corrected structure of the 5'flanking region of arylsulfatase gene of the sea urchin,Hemicentrotus pulcherrimus." Develop.Growth & Differ.36. 633-636 (1994)

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      1994 Annual Research Report
  • [Publications] T.Yamamoto: "A long polypyrimidine:polpurine sequence in 5'flanking region of arylsulfatase gene of sea urchin embryo." Int.J.Dev.Biol.38. 337-344 (1994)

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      1994 Annual Research Report
  • [Publications] Y.Iuchi: "Detection and characterization of the cis-element in the first intron of the Ars gene in sea urchin." Develop.Growth & Differ.37(in press). (1995)

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      1994 Annual Research Report
  • [Publications] H.Kobayashi: "Local change of an exogastrula-inducing peptide(EGIP)in the pluteus larva of the sea urchin Anthocidaris crassispina." Zool.Sci.11. 157-160 (1994)

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      1994 Annual Research Report
  • [Publications] Y.Fujuta: "A protein that binds an exogastrula-inducing peptide,EGIP-D,in the hyline layer of sea urchin embryos." Develop.Growth & Differ.36. 275-280 (1994)

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      1994 Annual Research Report
  • [Publications] K.Yamasu: "Molecular cloning of a cDNA that encodes the precursor to several exogastrulainducing peptides,EGF-related polypeptides of the sea urchin,A.crassispina." Eur.J.Biochem.(in press). (1995)

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      1994 Annual Research Report
  • [Publications] K.Oofusa: "Regionally and hormonally regulated expression of collages and collagenase in the anuran larval skin." Int.J.Dev.Biol.38. 345-350 (1994)

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  • [Publications] A.Kawai: "A three-step mechanism of action of thyroid hormone and mesenchyme in metamorphoric changes in anuran larval skin." Develop.Biol.166. 477-488 (1994)

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      1994 Annual Research Report
  • [Publications] T.Itoh: "Remodeling of human sperm chromatin mediated by nucleoplasmin from amphibian eggs" Development,Growth & Differentiation. 35. 59-66 (1993)

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      1993 Annual Research Report
  • [Publications] M.Moriya: "Immuno-electron microscopic localization of calmodulin and calmodulin-binding proteins in the mouse germ cells" Cell and Tissue Research. 271. 441-451 (1993)

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      1993 Annual Research Report
  • [Publications] K.Ohsumi: "Chromosome condensation in Xenopus mitotic extracts without histone Hl" Science. 262. 2033-2035 (1993)

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      1993 Annual Research Report
  • [Publications] N.Ariyoshi: "cDNA cloning and expression of Xenopus sperm-specific basic nuclear protein 5 (SP5) gene" Molecular Reproduction and Development. (in press). (1994)

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      1993 Annual Research Report
  • [Publications] Z.-S.Ji: "Mammalian follicle-stimulating hormone stimulates DNA synthesis in secondary spermatogonia and Sertoli cells in organ------." Zygote. (in press). (1994)

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      1993 Annual Research Report
  • [Publications] S.-I.Abe: "Initiation and stimulation of spermatogenesis in vitro by mammalian follicle-stimulating hormone in the japanese newt" International Journal of Developmental Biology. (in press). (1994)

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      1993 Annual Research Report
  • [Publications] K.Murata: "Isolation of H-SF substances,the high molecular weight precursors of egg envelope proteins from the scites-----" Zygote. 1. 315-324 (1993)

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      1993 Annual Research Report
  • [Publications] H.Yasuo: "Function of vertebrate T gene" Nature. 364. 582-583 (1993)

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  • [Publications] A.Hikosaka: "Regulated spatial expression of fusion gene constructs with the 5' upstream region of Halocynthia roretzi muscle actin gene---" Roux's Archives of Developmental Biology. 203. 104-112 (1993)

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  • [Publications] B.J.Swalla: "Novel genes expressed differentially in ascidians with alternate modes of development" Development. 119. 307-318 (1993)

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      1993 Annual Research Report
  • [Publications] I.Araki: "Expression of AMD1,a gene for a MyoD-related factor in the ascidian Halocynthia roretzi" Roux's Archives of Developmental Biology. 203(in press). (1994)

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      1993 Annual Research Report
  • [Publications] S.Fujiwara: "Temporal and spatial expression of a gene for the nuclear protein Hgv2 in embryos and adults of the ascidian------" Development,Growth & Differentiation. 35. 221-229 (1993)

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  • [Publications] N.Mizuno: "Localization of an exogastrula-inducing peptide(EGIP)in embryos of the sea urchin,Anthocidaris crassispina" Development,Growth & Differentiation. 35. 539-549 (1993)

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  • [Publications] Y.Chino: "Formation of the adult rudiment of sea urchins is influenced by thyroid hormones" Developmental Biology. 161. 1-11 (1994)

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      1993 Annual Research Report
  • [Publications] T.Yamamoto: "Structure and function of polypyrimidine-polypurine sequence in 5' flanking region of arylsulfatase gene of sea urchin embryo" International Journal of Developmental Biology. (in press). (1994)

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      1993 Annual Research Report
  • [Publications] K.Yamada: "Cis-elements and protein factors related to regulation of transcription of arylsulfatase gene during sea urchin development" Development,Growth & Differentiation. 35. 703-710 (1993)

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  • [Publications] H.Orii: "POU-domain genes in planalian Dugesia japonica:the structure and expression" Biochemical and Biophysical Research Communication. 192. 1395-1402 (1993)

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      1993 Annual Research Report
  • [Publications] Makoto Tabata: "Analysis of the formation of the animal-vegetal axis during Xenopus oogenesis using monoclonal antibodies." Devolopment,Growth and Differentiation. 34. 337-345 (1992)

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      1992 Annual Research Report
  • [Publications] Z.-S.Ji: "Differentiation from spermatogonia to primary spermaatocytes by follicle-stimulating hormone in organ culture of testes fragments from newt." Devolopment,Growth and Differentiation. 34. 649-660 (1992)

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  • [Publications] S.Abe: "How is the flagellar length of mature sperm determined?III.Comparison of initial rates of flagella in spermatide from Cynopus and Xenopus." Experimental Cell Research. 198. 373-374 (1992)

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      1992 Annual Research Report
  • [Publications] Shigeki Yasumasu: "Two constituet proteases of a teleostean hatcing enzyme:Concurrent synthesis and packaging in the same secretory granules in discrete arrangement." Devolopmental Biology. 149. 349-356 (1992)

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      1992 Annual Research Report
  • [Publications] Shigeki Yasumasu: "Isolation of cDNAs for LCE and HCE,two constituent proteases of the hatching enzyme of Oryzias latipes,and comcurrent expression of their mRNAs during development." Devolopmental Biology. 153. 250-258 (1992)

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      1992 Annual Research Report
  • [Publications] KenJiro Yamagami: "Molecular and cellular bases of formation,hardening and breakdown of the egg envelope in fish." International Review of Cytology. 136. 51-92 (1992)

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      1992 Annual Research Report
  • [Publications] Yuuji Seike: "Purification of a sperm lectin extracted from spermatzoa of the sea urchin,Hemicentrotus pulcherrimus." Development,Growth and Differentiation. 34. 285-291 (1992)

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      1992 Annual Research Report
  • [Publications] Kounosuke Kinoshita: "Maternal exogastrula-inducing peptides(EGIPs)and their changes during development in the sea urchin Anthocidaris crassispina." Development,Growth and Differentiation. 34. 661-668 (1992)

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      1992 Annual Research Report
  • [Publications] Kazuhiro Makabe: "Failure of muscle myosin heavy-chain expression in quarter ascidian embryos developed from the secondary muscle lineage cells." Zoological Sciences. 9. 569-573 (1992)

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      1992 Annual Research Report
  • [Publications] Takegiro Kusakabe: "Tunicate muscle actin genes:Structure and organization as a gene cluster." Journal of Molecular Biology. 227. 955-960 (1992)

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      1992 Annual Research Report
  • [Publications] Akira Hikosaka: "Introduction and expression of recombinant genes in ascidian embryo." Development,Growth and Differentiation. 34. 627-634 (1992)

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      1992 Annual Research Report
  • [Publications] Katsutoshi Yoshizato: "Death and transfomation of larval cells during metamorphosis of anura.(Review)" DEvelopment,Growth and Differentiation. 34. 607-612 (1992)

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      1992 Annual Research Report
  • [Publications] Keiko Mitsunaga-Nakatsubo: "Expression of Na^+,K^+-ATPase alpha-subunit in animalized and vegetalized embryos of the sea urchin,Hemicentrotus pulcherrimus." Development,Growth and Differentiation. 34. 677-684 (1992)

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      1992 Annual Research Report
  • [Publications] Kazumi Yamada: "Cis-acting elements for proper ontogenic expression of arylsulfatase gene of sea urchin embryo." Development,Growth and Differentiation. 34. 719-729 (1992)

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      1992 Annual Research Report
  • [Publications] 赤坂 甲治: "総説:ウニ初期発生における遺伝子発現の制御" 生化学. 64. 485-502 (1992)

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      1992 Annual Research Report

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Published: 1992-04-01   Modified: 2016-04-21  

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