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Fundamental of optogalvanic-Stark laser spectroscopy and its application to cell biology.

Research Project

Project/Area Number 04452108
Research Category

Grant-in-Aid for General Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field 応用物理学一般(含航海学)
Research InstitutionIBARAKI UNIVERSITY

Principal Investigator

FUJII Kanichi  Ibaraki University Fac.of Engineering Professor, 工学部, 教授 (00054354)

Co-Investigator(Kenkyū-buntansha) KUBOTA T.  ibid Lecturer, 工学部, 講師 (40143143)
KAMEMARU S.  ibid Assoc. Profes., 工学部, 助教授 (60175289)
Project Period (FY) 1992 – 1993
Project Status Completed (Fiscal Year 1993)
Budget Amount *help
¥6,900,000 (Direct Cost: ¥6,900,000)
Fiscal Year 1993: ¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 1992: ¥4,400,000 (Direct Cost: ¥4,400,000)
KeywordsOptohgalvanic / Stark / Laser / spectroscopy / Cell / Cancer / Gene
Research Abstract

This investigation is of one of the applications of optogalvanic laser spectroscopy and of laser Stark spectroscopy to the cell biology.
Under strong electric field, high lying excited level like Rydberg level is dispersed into several levels. If an excitation from a metastable state to one of these dispersed levels is carried out by tunable laser pumping, various emission spectra i different wavelength would be observed.
Using these spectroscopy, one can expect to give cells a desirable change and observe a specific fluorescence emission for detection of specific cell or for therapy of cancer cells.
Our aim has been in getting tunable wavelength from He-Cd^+ white-light laser by this means and apply it to cancer treatment by cutting the cancer gene only. Applying such laser spectroscopy, it would be expected that accurater detection of cells than that be cell sorter which uses scattering pattern can be done.
For getting final goal on this subject, however, several years are still necessary since we have no direct experimental system for cell treatment. Final check of our concept would be into the hands of another internatioonal project running in parallel.

Report

(3 results)
  • 1993 Annual Research Report   Final Research Report Summary
  • 1992 Annual Research Report
  • Research Products

    (32 results)

All Other

All Publications (32 results)

  • [Publications] M.Amano他(K.Fujii分担): "Application of the ILISPOT-ID19 system for the enumeration of different sizes of IgA spot forming cells in the murine small intestine" J.of Immunological Method. 164. 79-90 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] K.Oouchi他(K.Fujii分担): "Green-Yellow laser in CuBr-AgBr-Ne system operating at 40 kHz of repetition frequency" IEEE J.Quantum Electronics. 27. 2473-2481 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] M.Takashima他(K.Fujii分担): "Full color printer with a He-Ca^+ white light laser" Review of Scientific Instruments. 62. 1238-1245 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] T.Kubota他: "Facile synthesis of trifluoromethylated alcohols from trifluoroaddehyde ethyl hemiacetal" Tetrahedron Letters. 33. 1351-1354 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] S.Kamemaru他: "Fabrication of a character recognition system by a multipled matched spatial filtor by feature extracted patterns" Proceedings of SPIE. 1772. 157-162 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] S.Kamemaru他: "Charactor recognition by feature extraction using cross-correlation signals from a matched filter" Optical Engineering. 32. 26-32 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] M.Tkashima, S.Okada, H.Nishiyama and K.Fujii: "Full color printer with a He-Cd white-light laser" Review of Scientific Instruments. Vol.62. pp1328-1245 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] K.Oouchi, M.Suzuki, and K.Fujii: "Green-Yellow lasers in CuBr-AgBr-Ne systems operating at 40 kHz of repetition frequency" IEEE Journal of Quantum Electronics. Vol.21. pp2473-2481 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] M.Amano, J.R.McGhee, M.J.McCutcheon, K.Fyjii, and H.Kiyono: "Application of the ILISPOT-IDIP system for the enumeration of different sizes of IgA spot forming cells in the murine small and large intestine" Journal of Immunolog. Method. pp79-90 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] T.Kubota, M.Iijima and T.Tanaka: "Facile synthesis of a-Trifluoromethyl ated alchols from Trifluoroacetaldehy de Ethyl Hemiacetal" Tetrahedron Letters. vol.33. pp1351-1354 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] T.Kubota and M.Yamamoto: "Preparation of Phosphononium Salt from (S)-Trifluoropropene oxide and Witting type reactions" Tetrahedron Letters. vol.33. pp2603-2606 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] S.Kamemaru, S.Yamaguchi, and J.Yano: "Fabrication of a visual reception system using a microlens array in a hybrid pattern recognition system" Japanese J.of Appl.Physics. vol.31. pp1682-1688 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] S.Kamemaru and J,Yano: "Fabrication of a character recognition system by a multiplexed matched spatial filter by beature extracted patterns" Proceedings of SPIE. vol.1772. pp157-165 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] S.Kamemaru, H.Itoh, and J.Yano: "Character recognition by feature extraction using cross-correlation signals from a matched filter" Optical Engineering. vol.32. pp26-32 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] S.Kamemaru and T.Baba: "Pattern recognition system by a matched spatial filter and neutral networks for imperfect input characters" Proceedings of SPIE. vol.2026. pp185-193 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] M.Amano他(K.Fujii分担): "Application of the ILISPOT-IDIP system for the enumeration of different sizes of IgA spot forming cells in the murine small intestine" J.of Immunological Method. 164. 79-90 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] K.Oouchi他(K.Fujii分担): "Green-Yellow laser in CuBr-AgBr-Ne system operating at 40 kHz of repetition frequency" IEEE J.Quantum Electronics. 27. 2473-2481 (1992)

    • Related Report
      1993 Annual Research Report
  • [Publications] M.Takashima他(K.Fujii分担): "Full color printer with a He-Cd^+ white light laser" Review of Scientific Instruments. 62. 1238-1245 (1991)

    • Related Report
      1993 Annual Research Report
  • [Publications] T.Kubota他: "Facile synthesis of trifluoromethylated alcohols from trifluoro addehyde ethyl hemiacetal" Tetrahedron Letters. 33. 1351-1354 (1992)

    • Related Report
      1993 Annual Research Report
  • [Publications] S.Kamemaru他: "Fabrication of a character recognition system by a multipled matched spatial filter by feature extacted patterns" Proceedings of SPIE. 1772. 157-162 (1992)

    • Related Report
      1993 Annual Research Report
  • [Publications] S.Kamemaru他: "Charactor recognition by feature extraction using cross-correlation signals from a matched filter" Optical Engineering. 32. 26-32 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] G.Y. Yan,K-I.Fujii and A.L.Schawlow: "Relaxation-oscillator detection of optogalvanic spectra" Optics Letters. 15. 142-144 (1990)

    • Related Report
      1992 Annual Research Report
  • [Publications] M.Takashima,S.Okada,H.Nishiyama,M.Matsuda and K.Fujii: "Full color printer with a He-Cd^+ white-light laser" Revew of Scientific Instrument. 62. 1238-1245 (1991)

    • Related Report
      1992 Annual Research Report
  • [Publications] K.Oouchi,M.Suzuki and K.Fujii: "Green-Yellow lasers in CuBγ-AgBγ-Ne systems operating at 40 kHz of repetition frequency" IEEE Journal of Quantum Electronics. 27. 2473-2481 (1991)

    • Related Report
      1992 Annual Research Report
  • [Publications] 藤井 寛一: "He-Cd(金属イオン)レーザー" レーザー研究. 21. 32-35 (1993)

    • Related Report
      1992 Annual Research Report
  • [Publications] S.Kamemaru.T.Nagaoka M.Kakuta and I.Shimizu: "Multiple matched spacial filterlng with corresponding symbols by the bybrid system." Japanese J. of Applied Physics. 29. L1557-1560 (1990)

    • Related Report
      1992 Annual Research Report
  • [Publications] M.Aqu,A.Akiba T.Mochizuki and S.Kamemaru: "Multimatched filtering using a micro lens array" Applied Optics. 28. 4087-4091 (1990)

    • Related Report
      1992 Annual Research Report
  • [Publications] 矢野 潤一.亀丸 俊一: "特徴抽出された参照パターンによるマッチトフィルタと、それを用いた文字認識" 21. 319-326 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] S.Kamemaru,S.Yamaguchi and J.Yano: "Fabrication of a visual perception system using a micro lense array in hybrid patterm recogxition system." Japanese Journal of Applied Physics. 31. 1682-1688 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] S.Kamemaru,H.Itoh and J.Yano: "Charactor regtrition by feature extraction using cross-correlation signals from a matched" Optical Engineering. 32. (1993)

    • Related Report
      1992 Annual Research Report
  • [Publications] T.Kubota,M.Iijima and T.Tanaka: "Facile syrthesis of α-tyifluorome thylated alcohols from trifluoroacetaldehyde ethyl hemiacetal." Tetrahedron Letters. 33. 1351-1354 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] T.Kubota and M.Yamamoto: "Preparation of phosphonium salt from (S)-trifluoropropene oxide and wittig type reactions" Tetrahedron Letters. 33. 2603-2606 (1992)

    • Related Report
      1992 Annual Research Report

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Published: 1992-04-01   Modified: 2016-04-21  

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