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Study of atomic Ne penning laser for photodynamic therapy of cancer

Research Project

Project/Area Number 04452205
Research Category

Grant-in-Aid for General Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field 電子機器工学
Research InstitutionKeio University

Principal Investigator

OBARA Minoru  Keio Univ.Electrical Eng.Professor, 理工学部, 教授 (90101998)

Co-Investigator(Kenkyū-buntansha) KANNARI Fumihiko  ibid. Associate Professor, 理工学部, 助教授 (40204804)
Project Period (FY) 1992 – 1993
Project Status Completed (Fiscal Year 1993)
Budget Amount *help
¥6,200,000 (Direct Cost: ¥6,200,000)
Fiscal Year 1993: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1992: ¥4,700,000 (Direct Cost: ¥4,700,000)
Keywordspenning laser / photodynamic therapy / HpD / atomic laser / cancer treatment / noen laser / rare-gas laser / ペニング反応
Research Abstract

The atomic neon penning laser for photodynamic therapy of cancer is studied experimentally and theoretically. As a result, the following results are obtained :
(1)Using a neon penning laser code developed by us, the operational conditions for achieving high energy output and high efficiency are made clear.
(2)It is found that the optimun gas mixture is Ne/H_2=16/40 Torr and the optimum pumping rate is 0.5 MW/cm^3. At this parameter the output power density of 4.4 W/cm^3 is obtained at an efficiency of 8.5x10^<-6>.
(3)At higher pump rates than 0.5 MW/cm^3, deactivation of the upper laser level by discharge electron becomes larger, resulting in the decrease of the efficiency.
(4)Achievement of the stable discharge leads to the klowatt-class neon laser.
(5)As a penning partner of the neon laser, H_2 is better than D_2.
(6)By delivering the neon laser pulse through the quarts fiber, HpD is efficiently pumped.

Report

(3 results)
  • 1993 Annual Research Report   Final Research Report Summary
  • 1992 Annual Research Report
  • Research Products

    (6 results)

All Other

All Publications (6 results)

  • [Publications] C.H.Yang,K.Itoh,T.Araki,F.Kannari,M.Obara: "Output characteristics of high-pressure 585.3nm atomic neon laser pumped by transverse discharge" SPIE:Intense Laser Beams and Application. 1871. 57-61 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] C.H.Yang,K.Itoh,H.Tomita,M.Obara: "Scaling law of the atomic neon penning laser for photodynamic therapy of human cancer" J.Applied Physics. (発表予定).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] C.H.Yang, K.Itoh, T.Araki, F.Kannari, M.Obara: "Output characteristics of high-pressure 585.3nm atomic neon laser pumped by transverse discharge" SPIE. vol.1817. 57-61 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] C.H.Yang, K.Itoh, H.Tomita, M.Obara: "Scaling law of the atomic neon penning laser for photodynamic therapy of human cancer" J.Appl.Phys. (to be published).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Chuen-Huei Yang: "Output characteristics of high-pressure 585.3nm atomic neon laser pumped by transverse discharge" SPIE:Intense Laser Beams and Applications. 1871. 57-61 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Chuen‐Huei Yang: "Output characteristics of high‐pressure 585.3nm atomic neon laser pumped by transverse discharge" SPIE Vol.1871:Intense Laser Beams and Applications. 1871. (1993)

    • Related Report
      1992 Annual Research Report

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Published: 1992-04-01   Modified: 2016-04-21  

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