| Project/Area Number |
04454516
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| Research Category |
Grant-in-Aid for General Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
小児・社会系歯学
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| Research Institution | Hokkaido University |
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Principal Investigator |
ISHIKAWA Hiroyuki Hokkaido University, Dental Hospital, Lecturer, 歯学部・附属病院, 講師 (20184492)
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| Co-Investigator(Kenkyū-buntansha) |
UENO Takuro Hokkaido University, Dental School, Instructor, 歯学部, 助手 (70250462)
TOMOCHIKA Akira Hokkaido University, Dental School, Instructor, 歯学部, 助手 (20241341)
TSUCHIDA Takahiko Hokkaido University, Dental Hospital, Lecturer, 歯学部・附属病院, 講師 (00197708)
IMAI Tohru Hokkaido University, Dental School, Associate Professor, 歯学部, 助教授 (40160030)
NAKAMURA Shinji Hokkaido University, Dental School, Professor, 歯学部, 教授 (80001791)
山村 雅彦 北海道大学, 歯学部, 助手 (90220441)
松野 功 北海道大学, 歯学部, 助手 (60199825)
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| Project Period (FY) |
1992 – 1994
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| Project Status |
Completed (Fiscal Year 1994)
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| Budget Amount *help |
¥5,800,000 (Direct Cost: ¥5,800,000)
Fiscal Year 1994: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1993: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1992: ¥4,000,000 (Direct Cost: ¥4,000,000)
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| Keywords | Cleft Lip and Palate / Scar Tissue / Laser Doppler / Tissue Blood Flow / Dental Arch Form / Maxillary Growth / Palatoplasty / Diagnostic System / レーザードップラー / 上顎劣成長 / 歯列狭窄 / 口蓋裂 / レーザドップラー血流計 / 組織血流量 / 口蓋粘膜 / 大口蓋動脈 / 大口蓋孔 / 裂隙 / レーザドップラー効果 / 生体計測 |
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| Research Abstract |
Many investigators have reported that surgical repair of palatal clefts inhibits maxillary growth, and produces a distortion of the dental arch and a retrusion of the mid-face in cleft palate patients. Especially, mucoperiosteal denudation of palatal bone and scar tissue following the surgery are the major factors of these growth problems. The information about the scar tissue distributions on palates is important to growth studies of cleft palates and useful for orthodontic diagnosis, treatment planning and prognosis. However, it is difficult to identify the scar tissue visually, and there is no reliable method to determine scar tissue areas. To solve the problem, the laser doppler flowmeter was applied to differentiate the scar tissue from normal palate tissue. And effects of the scar tissue distributions on dental arch form and maxillary growth were investigated in this study. The following results were obtained.
1. By pressing larger palatine foramen, decrease in tissue blood flow was found on entire palatal surface in non-cleft subjects, but tissue blood flow was unchanged in the anterior portion of palates of cleft palate patients.
2. Histological obseservations suggested that the laser doppler flowmetry was effective to identify the scar tissue produced on the raw surface, based on the difference in circulatory conditions between the scar tissue and normal tissue.
3. The scar tissue distributions of cleft palate patients were divided into four types, and each type has a characteristic feature of a dental arch deformity.
4. There was no evident correlation between the scar tissue distributions and the maxillary growth.
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