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DIAGNOSIS OF METAL ALLERGY BYCOLORIMETRIC ANALYSIS OF PATCH TEST

Research Project

Project/Area Number 04557084
Research Category

Grant-in-Aid for Developmental Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field 補綴理工系歯学
Research InstitutionTOKYO MEDICAL AND DENTAL UNIVERSITY

Principal Investigator

INOUE Masayuki  TOKYO MED.&DENT.UNIV.NIASSOCIATE PROFESSOR, 歯学部, 助教授 (10013872)

Co-Investigator(Kenkyū-buntansha) MURATA Yukio  MURATA COLOR RESEACH RESEARCHER, 所長
NAGAI Shigemi  IWATE MED.UNIV.LECTURER, 歯学部, 講師 (20184476)
FURUKAWA Yoshitoshi  IWATE MED.UNIV.LECTURER, 歯学部, 講師 (40156956)
ISHIBASHI Kanji  IWATE MED.UNIV.PROFESSOR, 歯学部, 教授 (90018771)
村田 幸男  村田色彩エンジニヤリング, 所長
田端 恒雄  東京医科歯科大学, 歯学部, 教授 (20013849)
Project Period (FY) 1992 – 1994
Project Status Completed (Fiscal Year 1994)
Budget Amount *help
¥9,900,000 (Direct Cost: ¥9,900,000)
Fiscal Year 1994: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 1993: ¥1,200,000 (Direct Cost: ¥1,200,000)
Fiscal Year 1992: ¥7,300,000 (Direct Cost: ¥7,300,000)
KeywordsMETAL ALLERGY / DIAGNOSIS / PATCH TEST / SKIN COLOR / COLORIMETRIC ANALYSIS
Research Abstract

Patch tests have been used to determine the existence of metal allergy, and its severity was ascertained by the change in skin color. However, it was quite difficult to accurately assess the change in skin color at times. Therefore, a new colorimetric diagnostic system capable of objectively evaluating color was developed to overcome this problem. This was made possible with the aid of a computer and spectrophotometer capable of making longitudinal colorimetric studies and analysis. When this new diagnostic approach compared to the conventional subjective one, the following characteristics were obtained for positive testing ones :
1.Spectral reflectance curve was of the absorption type.
2.Depth of shade(Laberheta)increased.
3.A high color difference(dE)value was observed.
4.According to the Munsell system, the hue moved toward YR.
5.Lightness decreased and there was no change in chromaticity.
According to the CIELAB color system, there was a decrease in L^*, an increase in a^*, and a decrease in b^*.
In conclusion, characteristics of this new objective approach showed significant differences in dE,spectral reflectance curve, Laberheta, and L^*, a^*, b^*, and lightness when comparing the negative and positive groups.
We developed the diagnostic system(diagnostic formula)of the change in skin color utilized multivariate analysis on the basis of the results.

Report

(4 results)
  • 1994 Annual Research Report   Final Research Report Summary
  • 1993 Annual Research Report
  • 1992 Annual Research Report
  • Research Products

    (18 results)

All Other

All Publications (18 results)

  • [Publications] 松田もと子、永井成美 他: "パッチテストによる皮膚反応の色彩学的分析" 日本補綴歯科学会雑誌. 38. 588-595 (994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 割田研司 他: "金属アレルギーの疫学的調査-本学学生を対象としたパッチテストについて" 昭和歯科学会雑誌. 12. 319-324 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 重藤 直文 他: "金属アレルギーの口腔内アレルゲン金属除去後の経過について" 広島大学歯学雑誌. 25. 356-361 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 井上 昌幸: "金属アレルギーの現状と歯科領域における対応" 日本補綴歯科学会雑誌. 37. 1127-1138 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 井上昌幸 中山秀夫編: "歯科と金属アレルギー" デンタルダイヤモンド 東京, 197 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] MATSUDA,TOMOKO et al.: "COLORIMETRIC ANALYSIS OF THE SKIN REACTION BY PATCH TEST" J.JPN.PROSTHODONT.SOC.38. 588-595 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] WARITA,KENJI et al.: "AN EPIDEMIOLOGICAL RESEARCH OF METAL ALLERGY-PATCHTEST IN SHOWA UNIVERSITY DENTAL STUDENTS-" J.SHOWA UNIV.DENT.SOC.12. 319-324 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] SHIGETO,NAOFUMI et al.: "CLINICAL EVALUATION OF METAL ERUPTION AFTER REMOVING INTRAORAL ALLERGEN METAL" J.HIROSHIMA UNIV.DENT.SOC.25. 356-361 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] INOUE,MASAYUKI: "THE STATUS QUO OF THE METAL ALLERGY AND THE MESURES AGAINST IT IN DENTISTRY" J.JPN.PROSTHODONT.SOC.37. 1127-1138 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] SUZUKI,NORIKO: "STUDIES OM METAL ALLERGY IN THE FIELD OF DENTISTRY-TREATMENT WITH APPLICATION OF X-RAY FLORESCENCE SPECTROSCOPE ANALYSIS IN DETECTION OF ALLERGEN METALS" J.STOMATOL.SOC.JPN.61. 144-158 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] INOUE,MASAYUKI & NAKAYAMA,HIDEO: DENTISTRY AND METAL ALLERGY. DENTAL DIAMOND,TOKYO, 1993

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 井上昌幸: "金属アレルギーの現状と歯科領域における対応" 日本補綴歯科学会雑誌. 37. 1127-1138 (1993)

    • Related Report
      1994 Annual Research Report
  • [Publications] 松田もと子、永井成美他: "パッチテストによる皮膚反応の色彩学的分析" 日本補綴歯科学会雑誌. 38. 588-595 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] 井上 昌幸: "金属アレルギーの現状と歯科領域における対応" 日本補綴歯科学会雑誌. 37. 1127-1138 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 重藤 直文 他: "金属アレルギーの口腔内アレルゲン金属除去後の経過について" 広島大学歯学雑誌. 25. 356-361 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 割田研司 他: "金属アレルギーの疫学的調査-本学学生を対象としたパッチテストについて-" 昭和歯学会雑誌. 12. 319-324 (1992)

    • Related Report
      1993 Annual Research Report
  • [Publications] 井上昌幸 中山秀夫編: "歯科と金属アレルギー" デンタルダイヤモンド 東京, 197 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 井上 昌幸: "金属アレルギーの現状と歯科領域における対応" 日本補綴歯科学会雑誌. 36. 170 (1992)

    • Related Report
      1992 Annual Research Report

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Published: 1992-04-01   Modified: 2016-04-21  

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