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Development of self-mixing type laser Doppler frowmetry

Research Project

Project/Area Number 04557117
Research Category

Grant-in-Aid for Developmental Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field 医学一般
Research InstitutionKawasaki College of Allied Health

Principal Investigator

MITO Keiichiro  Kawasaki College of Allied Health Professions, Associate Professor, 医用電子技術科, 助教授 (40078027)

Co-Investigator(Kenkyū-buntansha) SHINOHARA Shigenobu  Shizuoka University, The faculty of Engineering, Professor, 工学部・電子工学科, 教授 (80022234)
Project Period (FY) 1992 – 1993
Project Status Completed (Fiscal Year 1993)
Budget Amount *help
¥1,300,000 (Direct Cost: ¥1,300,000)
Fiscal Year 1993: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1992: ¥1,000,000 (Direct Cost: ¥1,000,000)
KeywordsSelf-mixing effect / Doppler signal / Semiconductor laser diode / Near infra-red / Tissue blood flow / Multiple scattering / Photoimmunotherapy / Cancer treatment
Research Abstract

We investigated the characteristics of a self-mixed Doppler signal obtained from multiple moving targets with different velocity components theoretically and experimentally for the measurement of blood flow in tissue. The results showed that the self-mixed Doppler signal was linearly superimposed from each waveform of the different frequency components obtained from the multiple moving targets. The maximum frequency (Fmax) of the superimposed spectrum was estimated to be about 70% of the peak flow velocity of the multiple moving targets with different velocities. This value provides tentative criteria for judgment of tissue blood flow. Excellent linear relationships were obtained between the frequency (Fmax) of the blood velocity and the known blood flow velocity in the flow channel (0.994).

Report

(3 results)
  • 1993 Annual Research Report   Final Research Report Summary
  • 1992 Annual Research Report
  • Research Products

    (20 results)

All Other

All Publications (20 results)

  • [Publications] K.Mito: "Characteristics of laser Doppler flowmetry which is the different optical arrangement" Medical Engineeriny & Technology. 16. 236-242 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] K.Mito et al.: "Characteristics of local blood flow in the cancer graf to with difference of proliferative pattern in the nucle mice" Biorheolegy. 29. 58 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] K.Mito et al.: "SeH-mixing effect of the semiconductor laser Doppler method for blood flow measurement" Medical & Biological Engineering & Computing. 31. 308-310 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 三戸惠一郎: "ルミンを用いた近赤外光による光免疫癌治療法の研究" 医用電子と生体工学. 31. 367-370 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 三戸惠一郎、他: "自己混合型レーザ・ドプテ血流計の開発" 医用電子と生体工学. 31(特). 158 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 三戸惠一郎: "感光色素を用いた癌の光免疫学的治療法の基礎的検討" 医用電子と生体工学. 31(特). 348 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] K.Mito: "Characteristics of laser Doppler flowmetry which is the different optical arrangement." Medical Engineering & Technology. 16-6. 236-242 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] K.Mito et al.: "Characteristics of local blood flow in the cancer grafts with difference of proligerative pattern in the nude mice." Biorheology. 20-1. 58 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] K.Mito et al.: "Self-mixing effect of the semiconductor laser Doppler method for blood flow measurement." Medical & Biological Engineering & Computing. 31-3. 308-310 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] K.Mito: "Charactertics of Laser Doppler Howmetry whidis to Different of ticalmogment" Medical Engineering & Techuology. 16. 236-242 (1992)

    • Related Report
      1993 Annual Research Report
  • [Publications] K.Mito et al.: "Characteristics of Local blood flow in cancer grafts with difference of proferative pattern in mode mice." Biorheology. 29. 58 (1992)

    • Related Report
      1993 Annual Research Report
  • [Publications] K.Mito et al: "Self-mixing effect of the semiconductor laser Doppher method for blood flow measuremnet." Medical Biological Enjinering & Computing.31. 308-310 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 三戸,恵一郎: "ルミンを用いた近赤外光による光免疫癌治療法の研究" 医用電子と生体工学. 31. 367-370 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 三戸,恵一郎 他: "自己混合型レーザ・ドプラ血流計の開発" 医用電子と生体工学. 31(特). 158 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 三戸,恵一郎: "感光色素を用いた癌の光免疫学的治療法の基礎的検討" 医用電子と生体工学. 31(特). 348 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Keiichiro Mito et.al.: "Characteristics of local blood flow in the cancer grafts with difference of proliferative patlern in the nade mice" Biorheology(abstracts). 29. 58-58 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] Keiichiro Mito et al.: "Solf-mixing effect of the semiconductor laser Doppler method for blood flow masurement" Medical & Biological Engineering & Computing. 31. (1993)

    • Related Report
      1992 Annual Research Report
  • [Publications] Keiichiro Mito: "Characteristics of laser Doppler flowmeters with differing optical arrangemcnts" J.of Medical Engineering & Technology.

    • Related Report
      1992 Annual Research Report
  • [Publications] Shigenobu Shinohara et al.: "Novel Method of Vibrational Displacement Measarement Using Self-mixing Type LDV" Proceedings of the 31st SICE Annual Conteono(SICE'92). 1047-1050 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] Shigenobu Shinohara et al: "Compact and High-Precision Range Finder with Wide Dynamic Range and Its Application" IEEE Transactions on Instrumentation and Measurcment. 41. 40-44 (1992)

    • Related Report
      1992 Annual Research Report

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Published: 1992-04-01   Modified: 2016-04-21  

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