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Biological rhythm and womens's night-shift work : an occupational and physiological study of effects and mechanisms.

Research Project

Project/Area Number 04670300
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Hygiene
Research InstitutionHokkaido University

Principal Investigator

KOYAMA Akio  Department of Hygiene and Preventive Medicine, Hokkaido University School of Medicine, Associate professor., 医学部, 助教授 (90215202)

Co-Investigator(Kenkyū-buntansha) SAITO Takeshi  Department of Hygiene and Preventive Medicine, Hokkaido University School of Med, 医学部, 助手 (40153811)
Project Period (FY) 1992 – 1993
Project Status Completed (Fiscal Year 1993)
Budget Amount *help
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1993: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1992: ¥1,300,000 (Direct Cost: ¥1,300,000)
KeywordsBiological rhythm / Power spectral analysis / Blood pressure / Heart rate / Night work / Stress / Sex / 心電図 / R-R間隔変動 / 時系列解析 / 最大エントロピー法
Research Abstract

This study attempted 1) to establish a new method of time-series analysis for nonlinear physiological data , 2) to clarify the relationships between environmental, occupational and psycho-social factors of women's night-shift work utilizing a behavioral-medical approach, and 3) to elucidate the effects and their mechanisms on biological rhythm in the cardio-vascular system. Maximum entropy power spectral analysis and the least square method were performed to extract the periodic structure and the best fitting curves from physiological time-series data including blood pressure and heart rate recorded longer than 24 hours. As the residuals and their standard deviations between the raw data and the best fitting curves varied from only 10^<-8> to 10^<-9>, this method of analysis using artificial periodic functions is very effective to quantitatively evaluate changes of biological rhythm. Subjective fatigue symptoms at the end of work, and each phase (6 or 7 hours) of periods extracted from time-series data of blood pressure measured at 15 or 30 minutes interval, were similar for day- and nightshift workers. However, in the daytime after continuous night work, sleep with intermediate arousal accompanied by an increase in blood pressure and heart rate were observed. Psychological factors referred to as daily stress in addition to insufficient sleep may possibly have affected the biological rhythm. From the above, it is suggested that sleep in night-shift work and the reduction of daily stress are effective to maintain biological rhythm. Further, although the sexual differences of changes in biological rhythm by night-shift work were not clarified, the importance of health administration in the occupational fields is suggested, particulary in the recent process of the Ministry of Labor giving access to women to night-shift work.

Report

(3 results)
  • 1993 Annual Research Report   Final Research Report Summary
  • 1992 Annual Research Report
  • Research Products

    (12 results)

All Other

All Publications (12 results)

  • [Publications] 神山昭男: "心拍変動と自律神経機能-非線形・非定常時系列データの解析" 医学のあゆみ. 166. 574 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 神山昭男: "生体負担の測定と評価をめぐって" 人間工学. 29. 343-348 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 神山昭男: "ストレスと血圧および心拍数の周期変動" Therapeutic Research. 13. 2495-2497 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] KOYAMA, Akio: "Variation of Heart rate and Autonomic nervous function." Igaku no ayumi.166. 574 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] KOYAMA, Akio: "Mental Crisis of Japanese workers." Dig.Sci. of labor. 48. 764-768 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] KOYAMA, Akio. SAITO, Kazuo: "An agenda for measurements and evaluation of mental and physical workload" J.J.Ergonomics.29. 343-348 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] OHTOMO, Norio. et al.: "Non linear time-series analysis (5) An analysis of time-series data in medical and biological branches by the use of "MemCalc"" Bulletin of the Faculty of Eng. Hokkaido Univ.163. 35-46 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] KOYAMA, Akio: "Job stress and stress-related disease." Dig.Sci. of labor.47. 147-150 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 神山 昭男: "心拍変動と自律神経機能-非線形・非定常時系列データの解析" 医学のあゆみ. 166. 574 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 神山 昭男: "生体負担の測定と評価をめぐって" 人間工学. 29. 343-348 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 神山 昭男: "ストレスと血圧および心拍数の周期変動" Therapentic Research. 13. 2495-2497 (1992)

    • Related Report
      1993 Annual Research Report
  • [Publications] 大友 詔雄: "非線形時系列データ解析ー5.“MemCalc"を用いた医学・生物学分野の時系列解析ー" 北海道大学工学部研究報告. 163. 35-46 (1993)

    • Related Report
      1992 Annual Research Report

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Published: 1992-04-01   Modified: 2016-04-21  

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