| Project/Area Number |
04670710
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
Psychiatric science
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| Research Institution | Tokai University |
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Principal Investigator |
YAMAZAKI Kosuke Tokai University School of Medicine, Dept.of Psychiatry Professor, 医学部・精神科, 教授 (50147170)
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| Co-Investigator(Kenkyū-buntansha) |
KATO Yukiko Tokai University School of Medicine, Dept.of Psychiatry, Instructor, 医学部・精神科, 助手 (60246105)
MIZOGUCHI Kensuke Tokai University School of Medicine, Dept.of Psychiatry, Instructor, 医学部・精神科, 助手 (60219657)
HAYASHI Masatugu Tokai University School of Medicine, Dept.of Psychiatry Associate Professor, 医学部・精神科, 助教授 (30096250)
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| Project Period (FY) |
1992 – 1994
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| Project Status |
Completed (Fiscal Year 1994)
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| Budget Amount *help |
¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 1994: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1993: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1992: ¥600,000 (Direct Cost: ¥600,000)
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| Keywords | autistic disorders / early signs / infancy / check-list / Video record / eraly intervention / Logistic回帰分析 / 病因論的研究 |
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| Research Abstract |
The following two studies were conducted for extracting the early signs of autistic disorders through observation of infant behavior :
1) Evaluation utilizing a check-list :
A 24-item check-list was employed for evaluation of two groups of subjects : 188 cases of autistic children (146 boys, 42 girls ; 6.7<plus-minus>3.5 years), and 261 cases of normal control subjects (133 boys, 128 girls ; 1.8<plus-minus>0.8 years). The results were classified into four levels (I-IV) by Logistic Regresion Analysis. Items in Level I were the items with highest correlation to diagnoses of autism, but behavior falling under Level IV were regarded as holding deep significance in terms of the early si
2) Analysis of video tape recordings :
Video recording were evaluated in 8 cases (boys, age at first visit : 2 ; 0-4 ; 6 years) on whom home videos were available from before their disorders were noticed, dividing the records into three periods (Period I : 0 ; 0-0 ; 6 years, Period II : 0 ; 7-1 ; 0 years, Period III : 1 ; 1-2 ; 0 years). As results, it was found that disturbances in social interaction and emotional disorders were observable before 0 ; 6 years, and noted in all cases after 1 ; 1 years. Disorders in visual and auditory behavior were seen from 0 ; 3 years, including distinctive perceptual behavior. Disorders in muscle tonus and motor function were seen past 0 ; 7 years, and atypical behavior after 0 ; 9 years.
This study has provided a valuable key to early detection, although further comparative analysis against other developmental disorders and normal subjects are in order.
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