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A Clinical Psychiatric Study of Asperger's Syndrome

Research Project

Project/Area Number 04670719
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Psychiatric science
Research InstitutionTokyo University

Principal Investigator

KURITA Hirosh  Tokyo University, Faculty of Medicine, Professor, 医学部(医), 教授 (30010466)

Co-Investigator(Kenkyū-buntansha) KITA Michiko  National Institute of Mental Health, Subdivision head, 神経センター精神保健研究所, 室長 (60214780)
Project Period (FY) 1992 – 1994
Project Status Completed (Fiscal Year 1994)
Budget Amount *help
¥1,600,000 (Direct Cost: ¥1,600,000)
Fiscal Year 1994: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1993: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 1992: ¥700,000 (Direct Cost: ¥700,000)
KeywordsAsperger's syndrome / child psychiatry / developmental disorders / high-functioning autism / pervasive developmental disorders / アスペルガー症候群
Research Abstract

Twenty-eight cases with Asperger's syndrome (AS) (23male, 5female ; M=5.8years, SD=2.2) according to ICD-10 were compared with age- and sex-matched 20 cases of high-functioning (an IQ over 70) autism (HIA) and 75 cases with high-functioning PDD other than AS and HIA (HOPDD) in clinical variables. Fathers' ages at birth of the proband differed significantly among the three groups, with AS (M=33.5 years, SD=5.7) tended to be higher than the other two.
Father's educational level was significantly higher in AS than HIA.Speech developed significantly earlier in AS (M=13.5 months, SD=3.2) than HOPDD (M=19.1 months, SD=8.9) and HIA (M=24.3 months, SD=10.1) . Age at initial use of finger pointing was significantly earlier in AS (M=21.1 months, SD=13.9) than HIA (M=33.4 months, SD=11.8) . A Binet IQ was significantly higher in AS (M=105.1, SD=18.1) than HOPDD (M=85.9, SD=10.7) and HIA (M=85.0, SD=9.6) . Among the three groups, WISC-R full-scale and performance IQs measured in 36 cases did not differ significantly, whereas a verbal IQ did, with AS (M=101.9, SD=17.7) significantly higher than HOPDD (M=81.1, SD=10.8) and HIA (M=79.1, SD=20.7) . A total CARS-TV score, a measure of degree of autism, was significantly lower in AS (M=25.2, SD=3.2) than HIA (M=28.0, SD=3.5) . Incidence of genetic factor, EEG abnormality and epilepsy did not differ significantly among the three groups. AS seems to be milder disorder than HOPDD and HIA,with more close relatedness to HOPDD.

Report

(4 results)
  • 1994 Annual Research Report   Final Research Report Summary
  • 1993 Annual Research Report
  • 1992 Annual Research Report
  • Research Products

    (22 results)

All Other

All Publications (22 results)

  • [Publications] 栗田広: "発達障害" 精神科M00K. 28. 189-204 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 栗田広、北道子、勝野薫、矢部悦子: "アスペルガ-症候群と自閉症および特定不能の広汎性発達障害の比較研究" 安田生命社会事業団研究助成論文集. 27. 50-55 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 栗田広: "自閉的精神病質(アスペルガ-症候群)" 児童青年精神医学とその近接領域. 34. 300-301 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 栗田広: "アスペルガ-症候群" 病態生理. 13. 240-241 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 栗田広: "発達障害と気分変動" こころの健康. 9. 17-21 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Kurita,H.and Nakayasu,N.: "An autistic male presenting seasonal affective disorder(SAD)and trichotillomania" Journal of Autism and Developmental Disorders. 24. 687-692 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 栗田広: "広汎性発達障害の診断研究の動向 太田昌孝,永井洋子編著:自閉症治療の到達点" 日本文化科学社, 331-351 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 栗田広、畑中邦比古: "児童・青年期の広汎性発達障害" 全国心身障害児福祉財団, 251 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Kurita, H.: "Developmental disorders (in Japanese)" Psychiatric MOOK. 28. 189-204 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Kurita, H., Kita, M., Katsuno, K., Yabe, E.: "A comparative study of Asperger's syndrome, infantile autism and PDDNOS (in Japanese)" Research-aid Paper of the Yasuda Life Welfare Foundation. 29. 29-32 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Kurita, H.: "Autistische Psychopathie (Asperger's syndrome) (in Japanese)" Japanese Journal of Child and Adolescent Psychiatry. 34. 300-301 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Kurita, H.: "Asperger's syndrome (in Japanese)" Pathophysiology. 13. 240-241 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Kurita, H.: "Mood fluctuation in developmental disorders (in Japanese)" Japanese Journal of Mental Health. 17-21 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Kurita, H., Nakayasu, N.: "An autistic male presenting seasonal affective disorder and trichotillomania" Journal of Autism and Developmental Disorders. 24. 687-692 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 栗田広: "発達障害" 精神科MOOK. 28. 189-204 (1992)

    • Related Report
      1994 Annual Research Report
  • [Publications] 栗田広,北道子,勝野薫,矢部悦子: "アスペルガ-症候群と自閉症および特定不能の広汎性発達障害の比較研究" 安田生命社会事業団研究助成論文集. 27. 50-55 (1992)

    • Related Report
      1994 Annual Research Report
  • [Publications] 栗田広: "自閉的精神病質(アスペルガ-症候群)" 児童青年精神医学とその近接領域. 34. 300-301 (1993)

    • Related Report
      1994 Annual Research Report
  • [Publications] 栗田広: "アスペルガ-症候群" 病態生理. 13. 240-241 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] 栗田広: "発達障害と気分変動" こころの健康. 9. 17-21 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Kurita,H.and Nakayasu,N.: "An autistic male presenting seasonal affective disorder(SAD)and trichotillomania" Journal of Autism and Developmental Disorders. 24. 687-692 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] 栗田広: "広汎性発達障害の診断研究の動向.太田昌孝,永井洋子編著:自閉症 治療の到達点" 日本文化科学社, 331-351 (1992)

    • Related Report
      1994 Annual Research Report
  • [Publications] 栗田広,畑中邦比古: "児童・青年期の広汎性発達障害" 全国心身障害福祉財団, 251 (1993)

    • Related Report
      1994 Annual Research Report

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Published: 1992-04-01   Modified: 2016-04-21  

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