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Basic study of heart rate variability using chick embryo

Research Project

Project/Area Number 04807120
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Obstetrics and gynecology
Research InstitutionTakushoku University

Principal Investigator

KOBAYASHI Kenji  Takushoku University, Fac.of Eng., Professor, 工学部, 教授 (40016770)

Co-Investigator(Kenkyū-buntansha) KONDOH Shungo  Saitama Med.Scho., Toco.& Gyn., Assistant Professor, 産婦人科, 講師 (20178411)
HASEGAWA Jun  Takushoku University, Fac.of Eng., Research Associate, 工学部, 助手 (30228449)
Project Period (FY) 1992 – 1993
Project Status Completed (Fiscal Year 1993)
Budget Amount *help
¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 1993: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1992: ¥1,500,000 (Direct Cost: ¥1,500,000)
Keywordsheart beat / cardiotacogram / heart rate variability (HRV) / PVDF-sensor / chick embryo / embryonic movement / FHR-deceleration / fetal heart rate (FHR) / 胎児心拍数 / PVDF
Research Abstract

To make clear the relation of fetal heart rate variability (FHRV) with the environmental conditions, simulation experiments using chick embryo were made in following subjects.
1) picking up heart beat noninvasively from chick embryo
2) producing the cardiotacogram of chick embryo
3) control temperature and humidity in experimental box
4) measurement of HRV of chick embryo while changing temperature
5) dependency of O_2 and CO_2 on HRV of chick embryo
6) dependency of embryo movement on HRV of chick embryo
7)influence of other environmental factors (intensive magnetic field, electro-magnetic wave, ultrasonic wave) to HRV of chick embryo
The subjects of 1), 2) and 3) which is bearing basic instrumentation were realized. Heart beat was detected by the two methods of optical plethysmograph and phonocardiograph from 4 days after incubation, and the heart rate variability was obtained in relation to change of the environmental factors such as temperature, O_2 and CO_2 concentration and embryonic movement. The results of the simulation experiments by chick embryo showed the analogous phenomena to fetal heart rate variability (FHRV) of human being.

Report

(3 results)
  • 1993 Annual Research Report   Final Research Report Summary
  • 1992 Annual Research Report
  • Research Products

    (19 results)

All Other

All Publications (19 results)

  • [Publications] 野木一広: "鶏胚を用いた発生期の心拍数変動の測定" 医用電子と生体工学. 30,特別. 343-343 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 野木一広: "発生期の心拍数変動の測定とその要因" 信学技報(MBE). 92-53. 15-20 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 長谷川淳: "鶏胚の心音センサ" 日本音響学会秋季講演論文集. 473-474 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 長谷川淳: "鶏胚を用いた発生期の心拍数変動シミュレーション" 医用電子と生体工学(特別号). 31. 365 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] K.Kobayashi: "Heart Rate Measurement of chick Embryo for Interpretation of Fetal Heart Rate Variability." Proc.of the IMIA-IFMBE Working Conf.on Biosignal Interpretation.177-180 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] K.Kobayashi: "Heart Rate Measurementm of chick Embryo for Interpretation of Fetal Heart Rate Variability." Methods of Information in Medicine. 33(掲載予定). 1/94 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Nogi, K.: "Measurements of the Embryonic Heart Rate Variability using Egg.(in Japanese)" Japanese Journal of Medical Electronics and Biological Engineering. vol.30, suppl.343 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Nogi, K.: "Measurement of Chick Embryo's Heart Rate Variability.(in Japanese)" Technical Report of IEICE. MBE92-53. 15-20 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Hasegawa, J.: "Non-invasive Phono-cardiograph Sensor for Chick Embryo.(in Japanese)" Suppl.of the Acoustical Society of Japan. 473-474 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Hasegawa, J.: "Simulation experiment of Embryonic Heart Rate Variability under the environmental control using Chick Embryo.(in Japanese)" Japanese Journal of Medical Electronics and Biological Engineering. vol.31, suppl.365 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Kobayashi, K.: "Heart Rate Measurement of Chick Embryo for Interpretation of Fetal Heart Rate Variability." Proc.of the IMIA-IFMBE Working Conf.on Biosignal Interpretation. 177-180 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Kobayashi, K.: "Heart Rate Measurement of Chick Embryo for Interpretation of Fetal Heart Rate Variability." Methods of Information in Medicine. vol.33 (Scheduled). (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 長谷川淳: "鶏胚を用いた発生期の心拍数変動シミュレーション" 医用電子と生体工学(特別号). 31. 365 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] K.Kobayashi: "Heart Rate Measurementm of chick Embryo for Interpretation of Fetal Heart Rate Variability." Proc.of the IMIA-IFMBE Working Conf.on Biosignal Interpretation.177-180 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] K.Kobayashi: "Heat Rate Measurementm of chick Embryo for Interpretation of Fetal Heart Rate Variability." Methods of Information in Medicine. 33,(1/94掲載予定). (1994)

    • Related Report
      1993 Annual Research Report
  • [Publications] 野木 一広,長谷川 淳,小林 健二,近藤 俊吾: "鶏胚を用いた発生期の心拍数変動の測定" 医用電子と生体工学. 30,特別. 343-343 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 野木 一広,長谷川 淳,小林 健二,近藤 俊吾: "発生期の心拍数変動の測定とその要因" 信学技報(MBE). 92-53. 15-20 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 長谷川 淳,野木 一広,小林 健二,近藤 俊吾: "鶏胚の心音センサ" 日本音響学会秋季講演論文集. 473-474 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 小林 健二,長谷川 淳: "Detection of Chick embryo′s Heart Rate ーfor the simulation experiment of fetal Heart Rate Variability" 拓殖大学工学部研究報告. vol.3. 201-204 (1992)

    • Related Report
      1992 Annual Research Report

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Published: 1992-04-01   Modified: 2016-04-21  

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