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Investigation on Traditional Medicine in Buddhist Culture

Research Project

Project/Area Number 05045046
Research Category

Grant-in-Aid for international Scientific Research

Allocation TypeSingle-year Grants
SectionUniversity-to-University Cooperative Research
Research InstitutionToyama Medical and Pharmaceutical University

Principal Investigator

NAMBA Tsuneo  Prof., Research Institute for Wakan-Yaku, Toyama Med.and Pharm.Univ., 和漢薬研究所, 教授 (90028837)

Co-Investigator(Kenkyū-buntansha) 唐 暁軍  中国中医研究院, 中薬研究所, 助理研究員
KOMATSU Katsuko  Assist.Prof., Research Institute for Wakan-Yaku, Toyama Med.and Pharm.Univ., 和漢薬研究所, 助手 (50225570)
KADOTA Shigetoshi  Assoc.Prof., Research Institute for Wakan-Yaku, Toyama Med.and Pharm.Univ., 和漢薬研究所, 助教授 (90115163)
HU Shi-lin  Prof., Institute of Chinese Materia Medica, China Academy of Traditional Chinese, 中薬研究所, 教授
TANG Xiao-jun  Assist.Researcher, Institute of Chinese Materia Medica, China Academy of Traditi
宮代 博継  富山医科薬科大学, 和漢薬研究所, 助手 (00242511)
Project Period (FY) 1993 – 1995
Project Status Completed (Fiscal Year 1995)
Budget Amount *help
¥5,500,000 (Direct Cost: ¥5,500,000)
Fiscal Year 1995: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1994: ¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 1993: ¥2,000,000 (Direct Cost: ¥2,000,000)
KeywordsBuddhism / Ayurveda / Tibetan medicine / Chinese medicine / Traditional medicine / Comparative ethnopharmacology / Pharmacognostical study / Antidiabetic / Anti-HIV / アーユル・ヴェーダ / 抗糖尿病薬 / インド医学 / 難病,老化予防薬
Research Abstract

Buddhism was originated in Idia and its idea is said to be highly influenced by Ayurveda. Mahayanist Buddhism was spread over Tibet, Mongolia and China, together with Ayurveda. Some medical systems in such areas accepted as it is and others were modified according to the culture and resources. This investigation was carried out to clarify the characteristics of each traditional medicines by comparing their medical practices and crude drugs with those of Ayurveda and to find out some useful drugs. It has been focused on medical treatment performed in monastery (Chinese Buddhism-1a, Tibetan Buddhism-1b), Tibetan (2) and Mongolian (3) medicines, medical descriptions in Sutra (4) and an influence to Chinese medicine based on Taoism (5).
1a. In the center for Buddhism as Mt.Wutaishan, Mt.jiuhuashan and Fujian Province, medical practice was performed by priests who had learnt Chinese medicine, medicinal herbs and the way of massage, though such activities were in small number.
1b. Tibetan Budd … More hism attached a great importance on Tibetan medical science. Most of monasteries used to contain medical school and clinic, however the number of such monestry has been declined now.
2. Though Tibetan medicine followed the Ayurvedic principle, it had unique characteristic, that is , prescription pills were widely used, 70% of their ingredients were produced in Tibet, and most of them were aerial parts of alpine plants.
3. Mongolian medicine was characterized by the external treatment as brain-concussing therapy, bone settings, etc. and a dietetic treatment as Kumiss therapy.
4. Crude drugs described in "Mulasarvastivada-Vinayavastu" of "Vinaya-pitaka" were main Ayurvedic drugs.
5. The concepts of 404 diseases mentioned in "Sutra of Golden Lights" influenced to Chinese medicinal literatures as "Qianjinyaofang." During 6-8th century, Buddhism influenced to Chinese medicine.
6. The botanical origins of Tibetan crude drugs as sPru-nag, gYer-ma, etc. were determined through pharmacognostical study. The ethanol extract of Swertia mussotti (whole plant) was compared with S.japonica for their hypoglycemic activity and the active constituent was bellidifolin. Putranjivain A isolated from Phyllanthus emblica (fruit) showed inhibitory activity on reverse transcriptase as anti-HIV activity. Less

Report

(3 results)
  • 1995 Final Research Report Summary
  • 1994 Annual Research Report
  • 1993 Annual Research Report
  • Research Products

    (33 results)

All Other

All Publications (33 results)

  • [Publications] P.Basnet,S.Kadota,M.Shimizu,T.Namba: "Bellidifolin : A Patent Hypoglycemic Agent in Streptozotocin (STZ)-induced Diabetic Rats from Swertia japonica" Planta Medica. 60. 507-511 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] S.EL-Mekkawy,M.R.Meselhy,I.T.Kusumoto,S.Kadota,M.Hattori,T.Namba: "Inhibitory Effects of Egyptian Folk Medicines on Human Immunodeficiency virus reverse transcriptase" Chem.Pharm.Bull.43. 641-648 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] P.Basnet,S.Kadota,R.R.Pandey,T.Takahashi,Y.Kojima,M.Shimizu,Y.Takata,M.Kobayashi,T.Namba: "Screening of Traditional Medicines for their hypoglycemic activity in STZ-induced diabeticrats,and a detailed study of hypoglycemic activity on Psidium guajava" J.Trad.Med.12. 109-117 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] P.Basnet,S.Kadota,M.Shimizu,Y.Takata,M.Kobayashi,T.Namba: "Bellidifolin Stimulates Glucose Uptake in Rat 1 Fibroblasts and Ameliorates Hyperglycemia in Streptozotocin (STZ)-induced Diabetic Rats" Planta Medica. 61. 402-405 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] T.Namba,Z.M.Cu,G.C.Zhou,T.Z.Wang,M.Huo,K.Komatsu: "Pharmacognostical Study on the Chinese "Qiang-huo(羌活)," On the Anatomical Characteristics of the Underground Parts of Notopterygium incisum and N.forbesii" Natural Medicines. 49. 409-417 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] J.X.Li,S.Kadota,H.Y.Li,T.Miyahara,T.Namba: "The Effect of Traditional Medicines on Bone Resorption Induced by Parathyroid (PTH) in Tissue Culture : A Detailed Study on Cimicifugae Rhizoma" J.Trad.Med.13(印刷中). (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 伊 藤親,小松かつ子,劉 玉萍,施 大文,難波恒雄: "「花椒」及び「山椒」の生薬学的研究(第2報),Zanthoxylum亜属に由来する漢薬「花椒」,チベット薬物「gYer-ma」及びアーユルヴェーダ薬物「Tumburu」について" Natural Medicines. (投稿中).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] S.Yamaji,R.P.Yang,K.Komatsu,T.Z.Wang,T.Namba: "Pharmacognostical Studies on the Chinese Crude Drug "Xuelianhua" and Related Ethno-medicines (I),On Chinese crude drug "Xuelianhua" and Tibetan crude drug "Srol-gong" derived from Soroseris plants" J.Jpn.Bot.(投稿中).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] S.Yamaji,K.Komatsu,S.L.Hu,T.Namba: "Pharmacognostical Studies of the Tibetan Crude Drugs (10),On "sPang-spos" Derived from Nardostachys Plants" J.Jpn.Bot.(投稿中).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] S.Kadota,P.Basnet,E.Ishii,T.Tamura,T.Namba: "Antibacterial Activity of Trichorabdal A from Rabdosia trichocarpa Against Helicobacter pylori" Zentralblatt fur Bakteriologie. (投稿中).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] P.Basnet,S.Kadota,S.Yamaji,K.Komatsu,T.Namba: "A Comparative Study on Swertiae Herba from Japan,Nepal and China for their Hypoglycemic Activities in Streptozotocin (STZ)-induced Diabetic Rats" Natural Medicines. (発表予定).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 楊 瑞萍,山路誠一,小松かつ子,王 天志,難波恒雄: "「雪蓮花」類薬物の生薬学的研究(第2報),Saussurea属Eriocoryne亜属に由来する漢薬「雪蓮花」及びチベット薬物「Bya-rgod sug-pa」について" Natural Medicines. (発表予定).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 難波恒雄編: "生薬資源研究 第3輯 中国における仏教医学の調査研究" 富山医科薬科大学 和漢薬研究所(発表予定),

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] P.Basnet, S.Kadota, M.Shimizu, T.Namba: "Bellidifolin : A Patent Hypoglycemic Agent in Streptozotocin (STZ) -induced Diabetic Rats from Swertia japonica" Planta Medica. 60. 507-511 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] S.EL-Mekkawy, M.R.Meselhy, I.T.Kusumoto, S.Kadota, M.Hattori, T.Namba: "Inhibitory Effects of Egyptian Folk Medicines on Human Immunodeficiency virus reverse transcriptase" Chem.Pharm.Bull.43. 641-648 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] P.Basnet, S.Kadota, R.R.Pandey, T.Takahashi, Y.Kojima, M.Shimizu, Y.Takata, M.Kobayashi, T.Namba: "Screening of Traditional Medicines for their hypoglycemic activity in STZ-induced diabetic rats, and a detailed study of hypoglycemic activity on Psidium guajava" J.Trad.Med.12. 109-117 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] P.Basnet., S.Kadota, M.Shimizu, Y.Takata, M.Kobayashi, T.Namba: "Bellidifolin Stimulates Glucose Uptake in Rat 1 Fibroblasts and Ameliorates Hyperglycemia in Streptozotocin (STZ) -induced Diabetic Rats" Planta Medica. 61. 402-405 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] T.Namba, Z.M.Gu, G.C.Zhou, T.Z.Wang, M.Huo, K.Komatsu: "Pharmacognostical Study on the Chinese "Qiang-huo, " On the Anatomical Characteristics of the Underground Parts of Notopterygium inciswn and N.forbesii" Natural Medicines. 49. 409-417 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] J.X.Li, S.Kadota, H.Y.Li, T.Miyahara, T.Namba: "The Effect of Traditional Medicines on Bone Resorption Induced by Parathyroid (PTH) in Tissue Culture : A Detailed Study on Cimicifugae Rhizoma" J.Trad.Med. (in press). 13. (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] T.Namba (ed.): Research Institute for Wakan-Yaku, Toyama Medical and Pharmaceutical University (prearranged). Studia Bonorum Materierum Medica No.3, Investigation on Traditional Medicine in Buddhist Culture, (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] P.Basnet,S.Kadota,M.Shimizu,T.Namba: "Bellidifolin: A Patent Hypoglycemic Agent in Streptozotocin(STZ)-induced Diabetic Rats from Swertia japonica" Planta Medica. 60. 507-511 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] S.EL-Mekkawy,M.R.Meselhy,I.T.Kusumoto,S.Kadota,M.Hattori,T.Namba: "Inhibitory Effects of Egyptian Folk Medicines on Human Immunodeficiency virus reverse transcriptase" Chem.Pharm.Bull.43(掲載予定).

    • Related Report
      1994 Annual Research Report
  • [Publications] P.Basnet,S.Kadota,R.R.Pandey,T.Takahashi,Y.Kojima,M.Shimizu,Y.Takata,M.Kobayashi,T.Namba: "Screening of Traditional Medicines for their hypoglycemic activity in STZ-induced diabetic rats,and a detailed study of hypoglycemic activity on Psidium guajava" J.Trad.Med.(投稿中).

    • Related Report
      1994 Annual Research Report
  • [Publications] P.Basnet,S.Kadota,M.Shimizu,Y.Takata,M.Kobayashi,T.Namba: "Bellidifolin Stimulates Glucose Uptake in Rat 1 Fibroblasts and Ameliorates Hyperglycemia in Streptozotocin(STZ)-induced Diabetic Rats" Planta Medica. (投稿中).

    • Related Report
      1994 Annual Research Report
  • [Publications] T.Namba,Z.-M.Gu,G.-C.Zhou,T.-Z.Wang,M.Huo,K.Komatsu: "Pharmacognostical Study on the Chinese Crude Drug,“Qiang-huo(羌活)"" Natural Medicines. (投稿中).

    • Related Report
      1994 Annual Research Report
  • [Publications] S.Yamaji,K.Komatsu,S.-L.Hu,T.Namba: "Pharmacognostical Studies of the Tibetan Crude Drugs (9).On “sPang-spos"Derived from Nardostachys Plants" The Journal of Japanese Botany. (発表予定).

    • Related Report
      1994 Annual Research Report
  • [Publications] 伊藤親,小松かつ子,劉玉萍,施大文,難波恒雄: "「花椒」及び「山椒」の生薬学的研究(第2報),Zanthoxylum亜属に由来する「花椒」,「gYer-ma」,「Timbur」の基源について" Natural Medicines. (発表予定).

    • Related Report
      1994 Annual Research Report
  • [Publications] 難波恒雄,山路誠一,小松かつ子,王 天志,揚 瑞萍: "「雪蓮花」の生薬学的研究(第1報),Saussurea属Eriocoryne亜属に由来する「雪蓮花」及び「Bya-rgod sug-pa」について" Natural Medicines. (発表予定).

    • Related Report
      1994 Annual Research Report
  • [Publications] T.Namba,Z.-M.Gu,T.-Z.Wang,M.Huo,G.-C.Zhou,K.Komatsu: "Pharmacognostical Study on the Chinese Crude Drug“Qiang-huo(羌活)"" Shoyakugaku Zasshi. (発表予定).

    • Related Report
      1993 Annual Research Report
  • [Publications] S.Yamaji,K.Komatsu,S.-L.Hu,T.Namba: "Pharmacognostical Studies of the Tibetan Crude Drugs(9).On“sPang-spos"Derived from Nardostachys Plants" The Journal of Japanese Botany. (発表予定).

    • Related Report
      1993 Annual Research Report
  • [Publications] 小松かつ子,伊藤親,劉玉萍,難波恒雄: "花椒及び山椒の生薬学的研究,花椒及び関連生薬の基源について" 生薬学雑誌. (発表予定).

    • Related Report
      1993 Annual Research Report
  • [Publications] P.Basnet,S.Kadota,R.R.Pandey,T.Takahashi,Y.Kojima,M.Shimizu,T.Namba: "Screening of twenty three crude drugs for their hypoglycemic activity in STZ-induced diabetic rats.A detailed study of hypoglycemic activity on Psidium guajava." Ethnopharmacology. (発表予定).

    • Related Report
      1993 Annual Research Report
  • [Publications] S.EL-Mekkawy,M.R.Meselhy,I.T.Kusumoto,S.Kadota,M.Hattori,T.Namba: "Inhibitory Effects of Egyptian Folk Medicines on Human Immunodeficiency virus reverse transcriptase." Journal of Natural Products. (発表予定).

    • Related Report
      1993 Annual Research Report

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Published: 1993-04-01   Modified: 2016-04-21  

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