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Higher brain functions

Research Project

Project/Area Number 05267102
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Research InstitutionKyoto Pref.Univ.of Med.

Principal Investigator

TOYAMA Keisuke  Kyoto Pref.Univ.of Med., Dep.of Physiol., Prof., 医学部, 教授 (90090505)

Co-Investigator(Kenkyū-buntansha) TANJI Jun  Tohoku Univ., Fac.of Med., Prof., 医学部, 教授 (10001885)
TSUKADA Minoru  Tamagawa Univ., Fac.of Engineering, Prof., 工学部, 教授 (80074392)
SAKATA Hideo  Nihon Univ., Fac.of Med., Prof., 医学部, 教授 (10073066)
TSUMOTO Tadaharu  Osaka Univ., Fac.of Med., Prof., 医学部, 教授 (50028619)
AMARI Shunichi  Riken Inst., Director, 国際フロンティア, ディレクター (80010726)
Project Period (FY) 1993 – 1996
Project Status Completed (Fiscal Year 1996)
Budget Amount *help
¥106,000,000 (Direct Cost: ¥106,000,000)
Fiscal Year 1995: ¥15,900,000 (Direct Cost: ¥15,900,000)
Fiscal Year 1994: ¥58,600,000 (Direct Cost: ¥58,600,000)
Fiscal Year 1993: ¥31,500,000 (Direct Cost: ¥31,500,000)
Keywordscerebral cortex / hippocampus / cerebellum / motoe control / cognition / memory / covariance learning / sparse coding
Research Abstract

Recent development of the neuroscience recording technology including noninvasive recording of the human brain activities, multi-channel recording of neuronal activities, optical recording as well as that of the molecular neuroscience technology including gene-knock out, and drug design technique producing antisense for mRNA,and antagonists or agonists for receptors and second messengers made a direct approach possible to higher brain functions such as perception, learning, memory and behaviors. This project intended to produce a breakthrough in the study of the higher brain functions by theoretical and experimental verification of four major concepts in the neuroscience, 1) Covariance hypothesis, 2) Sparse representation, 3) Forward and inverse problems in perception, 4) Forward and inverse problems in motor controls.

Report

(5 results)
  • 1996 Annual Research Report   Final Research Report Summary
  • 1995 Annual Research Report
  • 1994 Annual Research Report
  • 1993 Annual Research Report
  • Research Products

    (61 results)

All Other

All Publications (61 results)

  • [Publications] Kurotani,T.: "Protein and RNA synthesis-dependent and-independent LTPs in developing rat visual cortex." Neuroreport. (in press).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Tanifuji,M.: "Optical responses evoked by white matter stimulation in rat visual cortical slices and their relation to neural activities." Brain Res.738. 83-95 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Toyama,K.: "Pre-and postnatal structures in the rat cerebral cortical circuitry." Basic Neurosci.in Invertebrates,ed.by Kidokoro et al.,Japan Scientific Society Press. 333-339 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Yamamoto,N.: "Repulsive and attractive mechanisms for the formation of corticofugal projections." Neuroreport. 6. 1517-1520 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Huang,J.: "A biomimetic system for localization and separation of multiple sound sources." IEEE Trans.IM. 44. 733-738 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Sato,H.: "Mechanisms underlying direction selectivity of neurons in the primary visual cortex of the macaque." J.Neurophysiol.74. 1382-1394 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Amari,S.: "Information geometry of the EM and em algorithms for neural networks." Neural Networks. 8. 1379-1408 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Sakata,H.: "Neural mechanisms of visual guidance of hand action in the parietal cortex of the monkey." Cerebral Cortex. 5. 429-438 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Hikosaka,O.: "Learning of sequential movements in the monkey-Process of learning and retention of memory." J.Neurophysiol.74. 1652-1661 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Miura,K.: ""Self-organization of the velocity selectivity of a directionally selective neural network." Biol.Cybern.73. 401-407 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 出村 公成: "動的類似度を用いたワンショット学習則" 日本神経回路学会誌. 2. 4-10 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Tsukada,M.: "Temporal pattern sensitivity of long-term potentiation in hippocampal CA1 neurons." Biol.Cybern.70. 495-503 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Inase,M.: "Thalamic distribution of projection neurons to the primary motor cortex relative to afferent terminal fields from the globus pallidus in macaque monkey." J.Comp.Neurol.353. 415-426 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Toyama,K.: "Brain and Memory,Modulation and Mediation of Neuroplasticity" McGauch,J.M.,Weinberger,N.M.and Lyuch,G., 350 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Kurotani, T.: "Protein and RNA systhesis-dependent and -independent LTPs in developing rat visual cortex." Neuroreport. (in press).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Tanifuji, M.: "Optical responses evoked by white matter stimulation in rat visual cortical slices and their relation to neural activities." Brain Res.738. 83-95 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Toyama, K.: "Pre-and postnatal strictures in the rat cerebral cortical circuitry." Basic Neurosci.in Invertebrates, ed.by Kidokoro et al., Japan Scientific Society Press. 333-339 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Yamamoto, N.: "Repulsive and attractive mechanisms for the formation of corticofugal projections." Neuroreport. 6. 1517-1520 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Huang, J.: "A biomimetic system for localization and separation of multiple sound sources." IEEE Trans.IM. 44. 733-738 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Sato, H.: "Mechanisms underlying direction selectivity of neurons in the primary visual cortex of the macaque." J.Neurophysiol. 74. 1382-1394 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Amari, S.: "Information geometry of the EM and em algoiethms for neural networks." Neural Networks. 8. 1379-1408 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Sakata, H.: "Neural mechanisms of visual guidance of hand action in the parietal cortex of the monkey." Cerebral Cortex. 5. 429-438 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Hikosaka, O.: "Learning of sequential movements in the monkey-Process of learning and retention of memory." J.Neurophysiol.74. 1652-1661 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Miura, K.: ""Self-organization of the velocity selectivity of a directionally selective neural network." Biol.Cybern.73. 401-407 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Tsukada, M.: "Temporal pattern sensitivity of long-term potentiation in hippocampal CA neurons." Biol.Cybern.70. 495-503 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Inase, M.: "Thalamic distribution of projection neurons to the primary motor cortex relative to afferent terminal fields from the globus pallidus in macaque monkey." J.Comp.353. 415-426 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Kurotani, T.: "Protein and RNA synthesis-dependent and-independent LTPs in developing rat visual cortex." Neuroreport. (in press).

    • Related Report
      1996 Annual Research Report
  • [Publications] Tanifuji, M.: "Optical responses evoked by white matter stimulation in rat visual cortical slices and their relation to neural to neural activities" Brain Res.738. 83-95 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Toyama, K.: "Pre-and postnatal structures in the rat cerebral cortical circuitry." Basic Neurosic. in Invertebrates, ed. by kidokoro et al. , Japan Scientific Society Press. 333-339 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Yamamoto, N.: "Roplsive and attractive mechanisms for the formation of corticofugal projections." Neuroreport. 6. 1517-1520 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] Huang, J.: "A biomimetic system for localization and separation of multiple sound sources." IEEE Trans. IM. 44. 733-738 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] Sato, H.: "Mechanisms underlying direction selectivity of neurons in the primary visual cortex of the macaque." J. Neurophysiol.74. 1382-1394 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] Amari, S.: "Information geometry of the EM and em algoiethms for neural networks." Neural Networks. 8. 1379-1408 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] Sakata, H.: "Neural mechaisms of visual guidance of hand action in the parietal cortex of the monkey." Cerebral Cortex. 5. 429-438 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] Hikosaka, O.: "Learning of seqential movements in the monkey-Process of learning and retention of memory." J. Neurophysiol.74. 1652-1661 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] Miura, K.: ""Self-organization of the velocity selectivity of a directionally selective neural network." Biol. Cybern.73. 401-407 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] 出村公成: "動的類似度を用いたワンショット学習則" 日本神経回路学会誌. 2. 4-10 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] Tsukada, M.: "Temporal pattern sensitivity of long-term potentiation in hippocampal CA1 neurons." Biol. Cybern.70. 495-503 (1994)

    • Related Report
      1996 Annual Research Report
  • [Publications] Inase, M.: "Thalamic distribution of projection neurons to the primary motor cortex relative to offerent terminal fieds from the globus pallidus in macague monkey." J. Comp. Neurol.353. 495-426 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] Toyama, K.: "Brain and Memory, Modulation and Mediation of Neuroplasticity" McGauch, J. M. , Weinberger, N. M. and Lynch, G., 350 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] Yamamot,N.: "Repulsive and attractive mechanisms for the formation of corticofugal projections." Neuroreport. 6. 1517-1520 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Huang,J.: "A biomimetic system for Localization and separation of multiple sound sources." IEEE Trans,IM. 44. 733-738 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Amari,S.: "Information geometry of the EM and em algoiethms for neural metworks." Neural Networks. 8. 1379-1408 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Sato,H.: "Mechanisms underlying direction selectivity of neurons in the primary visual cortex of the macaque." J.Neurophysiol.74. 1382-1394 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Sakata,H.: "Neural mechanisms of visual guidance of hand action in the parietal cortex of the monkey." Cerebral Cortex. 5. 429-438 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Hikosaka,O.: "Learning of sequential moyements in the monkey-Process of learning and retention of memory." J.Neurophysiol.74. 1652-1661 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Miura,K.: "“Self-organization of the velocity selectivity of a directionally selective neural network." Biol.Cybern.73. 401-407 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 出村 公成: "動的類似度を用いたワンショット学習則" 日本神経回路学会誌. 2. 4-10 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Tsukada,M.: "Temporal pattern sensitivity of long-term potentiation in hippocampal CA 1 neurons." Biol.Cybern.70. 495-503 (1994)

    • Related Report
      1995 Annual Research Report
  • [Publications] Inase,M.: "Thalamic distribution of projection neurons to the primary motor cortex relative to afferent terminal fields from the globus pallidus in macaque monkey." J.Comp,Neurol.353. 415-426 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Toyama,K.: "Brain and Memory,Modulation and Mediation of Neuroplasticity" Mc Gauch,J.M.,Weinberger,N.M.and Lynch,G., 350 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Toyama,K.: "Neuronal responsiveness in areas 19 and 21a,and the posteromedial lateral suprasylvian cortex of the cat." Exp.Brain Res.99. 289-301 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Yoshimura,Y.: "Dependence of LTP induction on postsynaptic depolarization:A perforated patch clamp study in visual cortical slices of young rats." J. Neurophysiol.71. 1638-1645 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Sakata,H.: "Functional properties of rotation-sensitive neurons in the posterior parietal association cortex of the monkey." Exp.Brain Res.101. 183-202 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Aizawa,H.: "Corticocortical and thalamocortical responses of neurons in the monkey primory motor cortex and their relation to atarained motor task." J.Neurophysiol.71. 550-560 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] 朱暁令: "画像中の半透明物体の重なりの検出" 電子情報通信学会論文誌. J77-D-II.2. 343-352 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Toyama,K.: "In vitro studies of visual cortical development and plosticity." Progress in Neurobiology. 41. 543-563 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Amari,S.: "A universal theorem on learning curves." Neural Networks. 6. 161-166 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Hata,Y.: "Development of local horizontal interactions in cat visual cortex studied by cross-correlation analysis." J.Neurophysiol.69. 40-56 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Hikosaka,O.: "Focal visual attention produces illusory temporal order and motion sensation." Vision Res.33. 1219-1240 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Tokuno,H.: "Input organization of distal and proximal forelimb areas in the monkey primary motor cortex;a retrograde double labeling study." J.Comp.Neurol.333. 199-209 (1993)

    • Related Report
      1993 Annual Research Report

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Published: 1993-04-01   Modified: 2016-04-21  

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