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The development of monochromatic X-ray computed tomography with synchrotron radiation

Research Project

Project/Area Number 05404037
Research Category

Grant-in-Aid for General Scientific Research (A)

Allocation TypeSingle-year Grants
Research Field Radiation science
Research InstitutionUniversity of Tsukuba

Principal Investigator

ITAI Yuji  Institute of Clinical Medicine, Univ.Tsukuba Professor, 臨床医学系・放射線医学, 教授 (30010268)

Co-Investigator(Kenkyū-buntansha) ANDO Masami  KEK Professor, 教授 (30013501)
TAKEDA Tohoru  Institute of Clinical Medicine, Univ.Tsukuba Assistant Prof., 臨床医学系・放射線医学, 講師 (10197311)
ISHIKAWA Nobuyoshi  Institute of Clinical Medicine Associate Prof., 臨床医学系・放射線医学, 助教授 (10026932)
Project Period (FY) 1993 – 1994
Project Status Completed (Fiscal Year 1994)
Budget Amount *help
¥33,200,000 (Direct Cost: ¥33,200,000)
Fiscal Year 1994: ¥13,200,000 (Direct Cost: ¥13,200,000)
Fiscal Year 1993: ¥20,000,000 (Direct Cost: ¥20,000,000)
Keywordssynchrotron radiation / monochromatic x-ray / computed tomography / high contrast resolution / diagnostic radiology / high contrast resolution / 放射光 / 単色X線 / computed tomograpy / 高分解能 / 画像診断 / 機能画像
Research Abstract

For biomedical diagnosis, a new monochromatic x-ray CT system using synchrotron radiation is being developed to obtain clear images and to detect low contrast materials for quantitative functional evaluation of organs in correspondence with their anatomical structures.
The SR-CT system is constructed at the beam line NE-5A of the Tristan Accumulation Ring in Tsukuba (6.5GeV,20-30mA). This system consists of a rotating x-ray shutter, a silicon (111) and silicon (511) double monochromator, an x-ray slits system, a roating object table, an x-ray linear array sensor system and a computer. By this system, the image with x-ray energy from 30 to 52 keV can be obtained to detect various contrast materials (iodine, barium and gadolinum). The x-ray linear arry sensor consists of BGO scintillators and a silicon photo-diode array. The dynamic range of the system is 60000 : 1 with 200mum of the spatial resolution. Image data was digitized by a 16 bit A/D converter and led to the computer. Exposure time of each projection can be changed from 3 ms to longer. Slice thickness of the object can be also adjustable from 0.1 to 3.2 mm using the slit system. Using a unix workstation, a SR-CT image is reconstructed from the line data obtained by x-ray linear array detector. This workstation can perform high speed image reconstruction using graphic accelerator board.
Using the double crystal monochromator, the high order x-ray contamination is eliminated. A new CCD detector have some problems at the junction of sensor, and this produced the artifact. As the machine trouble of AR ring occurred in 1994, the experiments of this system could not performed sufficiently. The detailed experiment will be performed in 1995.

Report

(3 results)
  • 1994 Annual Research Report   Final Research Report Summary
  • 1993 Annual Research Report
  • Research Products

    (31 results)

All Other

All Publications (31 results)

  • [Publications] Takeda T: "High spatial resolution CT with a synchrotron radiation system." Journal of Computer Assisted Tomography. 18. 98-101 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 武田徹: "放射光を利用した微量元素分析型CT開発" 新医療. 230. 72-76 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Itai Y: "Application of Synchrotron Radiation to Medicine" INVESTIGATIVE RADIOLOGY. 28. 158-159 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 武田 徹: "放射光を用いた微量元素検出型単色X線CTの開発" INNERVISION. 8. 120-124 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Takeda T: "Detectability of tracer materials in synchrotron radiation computed tomography" Medical Imaging Technology.11. 405-406 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 武田 徹: "放射光CTの開発動向" Med.Imag.Tech.11. 621-627 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Takeda T,Itai Y,Hayashi K,Nagata Y,Yamaji H,Hyodo K.: "High spatial resolution CT with a synchrotron radiation system." Journal of Computer Assisted Tomography. 18 (1). 98-101 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Takeda T,Itai Y,Yoshioka H,Umetani K,Ueda K,Akisada M.: "Synchrotron radiation cine K-edge energy subtraction coronary arteriography using an iodine filter method." Medical & Biological Engineering & Computing. 32. 462-468 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Takeda T,Ito T,Kishi K,Maeda T,Yuasa T,Wu J,Kazama M,Hyodo K,Akatsuka T,Itai Y.: "Preliminary experiment of the fluorescent x-ray computed tomography with synchrotron radiation." Medical Imaging Technology. 12 (4). 537-538 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Itai Y,Takeda T: "Application of Synchrotron Radiation to Medicine Two-Dimensional Intravenous Coronary Arteriography and Monochromatic X-Ray Computed Tomography" Investigative Radiology. 28 (3). 158-159 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Umetani K,Ueda K,Takeda T,Itai Y,Akisada M,Nakajima T: "Iodine filter imaging system for subtraction angiography using synchrotron radiation." Nucl.Instr.Meth.A335. 569-579 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Zeniya T,Takeda T,Hyodo K,Akatsuka T,Hiranaka Y,Yuasa T,Tamura A,Uchida A,Wu J,Ishikawa N,Itai Y: "Detectability of tracer materials in synchrotron radiation computedtomography" Medical Imaging Technology. 11. 405-406 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Uyama C,Toyofuku F,Naito H,Endo M,Takeda T,Itai Y,Saito T,Nishimura K,Hyodo K,Ando M: "Monochromatic X-ray source obtained by characteristic X-ray for X-ray CT" Photon Factory Activity Report. 10. 413 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Takeda T,Zeniya T,Hyodo K,Akatsuka T,Yuasa T,Hiranaka Y,Wu J,Ishikawa N,Itai Y: "Synchrotron radiation computed tomography for biochemical use" Photon Factory Activity Report. 10. 411 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Umetani K,Ueda K,Takeda T,Anno I,Itai Y,Akisada M: "Two-dimensional real-time imaging system for subtraction angiography using an iodine filter" Rev.Sci.Instrum.63 (1). 629-631 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Uyama C,Toyofuku F,Naito H,Endo M,Takeda T,Nishimura K,Saito T,Hyodo K,Ando M: "Monochromatic X-ray CT using fluorescent X-ray generated by synchrotron radiation" Proc.of 4th Inter.Conf.Biophysics and Synchrotron Radiation. 9. 335 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Takeda T,Akatsuka T,Hyodo K,Itai Y,Hiranaka Y,Zeniya T,Yuasa T,Satoh M,Wu J,Ishikawa N,Nemoto H: "Synchrotron radiation computed tomography for biomedical use" Proc.of 4th Inter.Conf.Biophysic and Synchrotron Radiation. 9. 336 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Takeda T: "High spatial resolution CT witha synchrotron radiation system." Journal of Computer Assisted Tomography. 18. 98-101 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] 武田徹: "放射光を利用した微量元素分析型CT開発" 新医療. 230. 72-76 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Itai Y: "Application of Synchrotron Radiation to Medicine Two-Dimensional Intravenous Coronary Arteriography and Monochromatic X-Ray Computed Tomography" INVESTIGATIVERADIOLOGY. 28. 158-159 (1993)

    • Related Report
      1994 Annual Research Report
  • [Publications] Takeda T: "Detectability of tracer materials in synchrotron radiation computedtomograohy" Medical Imaging Technology. 11. 405-406 (1993)

    • Related Report
      1994 Annual Research Report
  • [Publications] 武田 徹: "放射光を用いた微量元素検出型単色X線CTの開発" INNERVISION. 8. 120-124 (1993)

    • Related Report
      1994 Annual Research Report
  • [Publications] 武田 徹: "放射光CTの開発動向" Med.Imag.Tech.11. 621-627 (1993)

    • Related Report
      1994 Annual Research Report
  • [Publications] Takeda T.,Itai Y.,et al:"High spatial resolution CT with a synchrotron radiation system." J.Computer Assisted Tomography. 18. 98-101 (1994)

    • Related Report
      1993 Annual Research Report
  • [Publications] 武田徹、板井悠二、他: "放射光を利用した微量元素分析型CT開発。" 新医療. 230. 72-76 (1994)

    • Related Report
      1993 Annual Research Report
  • [Publications] Itai Y,Takeda T: "Application of Synchrotron Radiation to Medicine" Investigative Radiology. 28(3). 158-159 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 武田徹、板井悠二: "放射光を用いた微量元素検出型単色X線CTの開発" INNERVISION. 8(1). 120-124 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 武田徹、板井悠二、他: "放射光CTの開発動向" Med.Imag.Tech.11(5). 621-627 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Itai Y.,Kurosaki Y.,et al:"Micronodular focal fatty infiltration of the liver." RoFo. 159. 402-404 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Itai Y.,Kurosaki Y.: "Hepatic cirrhosis." Mosby St.louis, (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Itai Y.,Ohtomo K.: "Clinical application of computed tomography in the liver." Georg Thieme,Stutugart., (1993)

    • Related Report
      1993 Annual Research Report

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Published: 1993-04-01   Modified: 2016-04-21  

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