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Analysis on Ancient Social Structure by using DNA Technology.

Research Project

Project/Area Number 05405003
Research Category

Grant-in-Aid for General Scientific Research (A)

Allocation TypeSingle-year Grants
Research Field 広領域
Research InstitutionUniversity of Tokyo

Principal Investigator

UEDA Shintaroh  University of Tokyo, Graduate School of Science, Associate Professor, 大学院・理学系研究科, 助教授 (20143357)

Project Period (FY) 1993 – 1995
Project Status Completed (Fiscal Year 1995)
Budget Amount *help
¥31,000,000 (Direct Cost: ¥31,000,000)
Fiscal Year 1995: ¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 1994: ¥8,000,000 (Direct Cost: ¥8,000,000)
Fiscal Year 1993: ¥20,000,000 (Direct Cost: ¥20,000,000)
KeywordsAncient Social Structure / DNA / burial / site / kinship / population structure / Yayoi era / Kofun era / 古代社会 / DNA分析 / 社会構造 / 古代DNA / 分子進化
Research Abstract

Individual identification of ancient human remains is one of the most fundamental requisites for studies of palaco-population genetics including kinship among ancient people, intra-and inter-population structures in ancient times, and the origin of human populations. However, knowledge of these subjects has been based mainly on circumstantial archacological evidence for kinsip and intra-population structure and on genetic studies of modern human populations. Here 1 performed individual identification of ancient humans using short-nucleotide tandem repeat and mitochondrial DNAs as genetic markers. The application of this approach to kinship analysis showed clearly the presence or absence of kinship among the ancient remains examined. furthermore, I determined nucleotide sequence data of mitochondrial DNA of ancient Japanese of "Yayoi" cra using skeletons excavated from the Takuta-Nishibun site. This site located on the northern Kyushu shows a diversity in burial type of human remains. Nucleotide sequnces of the major non-coding region of the mitochondrial DNA are determined from the 26 "Yayoi" individuals. Nucleotide sequence diversity shows that the "Yayoi" people of the Takuta-Nishibun site is not a genetically isolated population. Phenetic tree analysis indicates a statistically significant corrclation between burial type and genetic background of the Takuta-Nishibun individuals, and shows no discrete pattern clustering the "Yayoi" people or the "Jomon" people and carly modern Ainu.

Report

(4 results)
  • 1995 Annual Research Report   Final Research Report Summary
  • 1994 Annual Research Report
  • 1993 Annual Research Report
  • Research Products

    (22 results)

All Other

All Publications (22 results)

  • [Publications] Kurosaki,K.: "Individual DNA identification from ancient human remains." Amer. J. Hum. Genet.53. 638-643 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Watanabe,Y.: "Characterization of human-specific DNA regions obtained by genome subtraction." Hum. Evol.10. 63-68 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Oota,H.: "A genetic study of 2,000-year-old human remains from Japan using mitochondrial DNA sequences." Amer. J. Phys Anthropd.98. 133-145 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Kurosaki,K.: "Sequence variation found in the flantry region of a trimeric short tandem repeat at the PLA2 locus" Jap. J. Leg. Med.50(印刷中). (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Kurosaki K., Oota H., Saitoh H., Kiuchi M., and Ueda S.: "Sequence variation found in the flanking region of a trimeric short tandem repeat at the PLA2 locus : its considerable effect on estimating alleles." Jap.J.Legal Med.(in press). (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Oota H., Saitou N., Matsushita T., and Ueda S.: "A genetic study of 2,000-year-old human reamins of Japan (Yayoi period) using mitochondrial DNA sequences." Amer.J.Phys.Anthropol.98. 133-145 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Watanabe Y.and Ueda S.: "Characterization of human-specific DNA regions obtained by genome subtraction." Human Evolution. 10. 63-68 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Kurosaki K., Matsushita T., and Ueda S.: "Individual DNA identification from ancient human remains." Amer.J.Human Genet.53. 638-643 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Oota,H: "A Genetic Study of 2,000-Year-Old Human Remains From Japan Using mitochondrial DNA sequences" American Journal of Physical Anthropology. 98. 133-145 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Kurosaki,K: "Sequence Variation Found in the Flankry Region of a Trimeric short Tandem Repeat at the PLA2 locas" Japanese Journal of Legal Medicine(印刷中). 50. (1996)

    • Related Report
      1995 Annual Research Report
  • [Publications] Oota,H: "Genetic Study of Ancient Human Remains 2,000 Year Old of Japan(Yayoi Period) Using Mitochondrial DNA sequences" Anthropological Sciences. 103. 186 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Saitoh,H: "Application for Population Studies of STR polgmorphisins" Anthropological Sciences. 103. 185 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 植田信太郎: "古代試料を用いたDNA分析" 細胞工学. 14. 1036-1040 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 植田信太郎: "Ancient DNA" 蛋白質・核酸・酵素(印刷中). (1996)

    • Related Report
      1995 Annual Research Report
  • [Publications] 植田信太郎: "分子進化-解析の技法とその応用-(印刷中)" 共立出版, (1996)

    • Related Report
      1995 Annual Research Report
  • [Publications] Oota H.: "Successful PCR-amplification and sequencing of 26 mtDNA from 2,000 year old human remains" Anthropological Sciences. 103(印刷中). (1995)

    • Related Report
      1994 Annual Research Report
  • [Publications] Saitoh H.: "Application for population studies of STR polymorphisms" Anthropological Sciences. 103(印刷中). (1995)

    • Related Report
      1994 Annual Research Report
  • [Publications] Miura T.: "Phylogenetic subtypes of human T-lymphotropic virus type 1 and their relations to the anthropological background" Proc.Natl.Acad.Sci.USA. 91. 1124-1127 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Saitou N.: "Evolutionary rate of insertions and deletions in non-coding nucleotide sequences of primates" Mol.Biol.Evol.11. 504-512 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] 植田信太郎: "DNA多型 第2巻「マイクロサテライトの多型と応用」" DNA多型研究会(東洋書店), 233 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Kurosaki,K: "Individual DNA identification from ancient human remains." American Journal of Human Genetics. 53. 638-643 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Saitou,N: "Evolutionary rate of insertions and deletions in non-coding nucleotide sequences" Molecular Biology and Evolution. (印刷中). (1994)

    • Related Report
      1993 Annual Research Report

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Published: 1993-04-01   Modified: 2016-04-21  

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