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A study of preventive medicine on the individual variations in physico-endocrinological responses to stress

Research Project

Project/Area Number 05454234
Research Category

Grant-in-Aid for General Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field Public health/Health science
Research InstitutionNational Institute for Environmental Studies

Principal Investigator

KABUTO Michinori  National Institute for Environmental Studies, Project Chief, 地域環境研究グループ, 総合研究官 (00113481)

Co-Investigator(Kenkyū-buntansha) IMAI Hideki  National Institute for Environmental Studies, Researcher, 地域環境研究グループ, 研究員 (00232596)
KAGEYAMA Takayuki  National Institute for Environmental Studies, Senior Researcher, 地域環境研究グループ, 主任研究員 (90204346)
Project Period (FY) 1993 – 1995
Project Status Completed (Fiscal Year 1995)
Budget Amount *help
¥5,500,000 (Direct Cost: ¥5,500,000)
Fiscal Year 1995: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1994: ¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 1993: ¥2,200,000 (Direct Cost: ¥2,200,000)
Keywordsstress / physiology / endocrinology / CV-RR / CV-RR
Research Abstract

The RSA (respiratory sinus arrythmia), related to cardiac parasympathetic activity (PA), and MWSA (Mayr Wave sinus arrythmia), related to sympathetic activity (SA), components derived from spectral analysis of cardiac R-R intervals at rest were examined first for their relations with age, diet and obesity, which were found to be significant modulators, whereas stress-related personality and various stressors were not related. In the study on patients with panic disorders, the mean MWSA/RSA ratio as a more specific indication of SA was in the order of panic disorder>generalized anxiety disorder>controls, suggesting the feasibility of the methods as well as the hyperexcitation of the SA in the disorder as has been pointed out. An examination on the office workers revealed, moreover, MWSA/RSA ratio at awakeing rest correlated significantly with overworking time as well as commuting time. Finally, we clarified the correlation with sleep stage and the MWSA/RSA ratio showing the lowest value at deep sleep stage with a suggestion that the difference in the MWSA/RSA ratio between awaking rest and deep sleep may reflect mental stress at awaking rest as a new index.

Report

(4 results)
  • 1995 Annual Research Report   Final Research Report Summary
  • 1994 Annual Research Report
  • 1993 Annual Research Report
  • Research Products

    (22 results)

All Other

All Publications (22 results)

  • [Publications] 南 正信: "指尖容積波反応からみたホワイトノイズ刺激に対する交感神経系反応の個人差について" 日本衛生学雑誌. 48. 646-654 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 兜 眞徳: "脳と行動-脳内ストレス反応メカニズムから見たタイプA行動パターン" 労働衛生. 7(412). 66-67 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Kageyama T,: "Combined effects of mental workload and following exposure to road traffic noise on sympathetic activities assessed bya spectral component of heart rate variability." Arch complex Environ studies. 7. 13-20 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Kageyama T,: "A standardization method for respiratory sinus arrhythmia useing breathing frequency(the 2nd report):Efficieny of assessing changes in cardiac parasympathetic activity with posture" J Occupational Health. (in press). (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Kageyama T,: "A standardization method for respiratory sinus arrhythmia as an index of cardiac parasympathetic activity based on breathing frequency" J Occupational Health. (in press). (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 影山隆之: "タイプA傾向と喫煙・飲酒・仕事・肥満" タイプA. (印刷中). (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 南 正信: "指尖容積波反応からみたホワイトノイズ刺激に対する交感神経系反応の個人差について" 日本衛生学雑誌. 48. 646-654 (1993)

    • Related Report
      1995 Annual Research Report
  • [Publications] 兜 眞徳: "脳と行動-脳内ストレス反応メカニズムから見たタイプA行動パターン" 労働衛生. 7(412). 66-67 (1994)

    • Related Report
      1995 Annual Research Report
  • [Publications] Kageyama T,: "Combined effects of mental workload and following exposure to road traffic noise on sympatheticactivities assessed bya spectral component of heart rate variability." Arch complex Environ studies. 7. 13-20 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Kageyama T,: "A standardization method for respiratory sinus arrhythmia useing breathing frequency(the 2nd report): Efficieny of assessing changes in cardiac parasympathetic activity with posture" J Occupational Health. (in press). (1996)

    • Related Report
      1995 Annual Research Report
  • [Publications] Kageyama T,: "A standardization method for respiratory sinus arrhythmia aa an index of cardiac parasympathetic activity based on breathing frequency" J Occupational Health. (in press). (1996)

    • Related Report
      1995 Annual Research Report
  • [Publications] 影山隆之: "タイプA傾向と喫煙・飲酒・しごと・肥満" タイプA. (印刷中). (1996)

    • Related Report
      1995 Annual Research Report
  • [Publications] 兜真徳,影山隆之,加藤道昌,飯田英晴: "心拍間隔変動の自己相関スペクトル成分を用いた自律神経機能評価(その1)パニック症候群についての検討" ストレス科学. 9(2). 87- (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] 影山隆之、兜真徳: "精神作業後の騒音暴露による生理反応:心拍変動成分による自律神経系活動を指標として。" 日本騒音制御工学会技術発表会講演論文集. 197-200 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] 今井秀樹、厳康敏、影山隆之、新田裕史、兜真徳: "心臓自立神経系活動性の変動要因について;尿中カテコールアミン排泄速度との関連" 日本衛生学雑誌. 49. 251 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] 影山隆之、今井秀樹、新田裕史、兜真徳: "心臓自律神経系活動性の変動要因について;呼吸速度・食事・運動との関連" 日本衛生学雑誌. 49(1). 250- (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] 錦戸典子、兜真徳、金子晋也、影山隆之、今井秀樹、本田靖: "心拍変動成分を用いた心臓系自律神経機能検査法(第3報)減量指導効果判定への適用の試み" 産業医学. 36. 317- (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] 影山隆之、兜真徳、今井秀樹: "精神作業と騒音暴露が心臓系自律神経機能(心拍変動成分による)を及ぼす複合影響" 産業医学. 36. 485- (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] 兜真徳、錦戸典子、影山隆之、今井秀樹、本田靖、金子哲也: "心拍変動成分を用いた自律神経機能検査法(第2報)加令、肥満、喫煙との関連" 産業医学. 36. S316- (1994)

    • Related Report
      1993 Annual Research Report
  • [Publications] 錦戸典子、兜真徳、影山隆之、今井秀樹、本田靖、金子哲也: "心拍変動成分を用いた自立神経機能検査法(第3報)減量指導効果判定への適用の試み" 産業医学. 36. S317- (1994)

    • Related Report
      1993 Annual Research Report
  • [Publications] 影山隆之、今井秀樹、新田裕史、兜真徳: "心臓自律神経系活動性の変動要因について:呼吸速度・食事・運動との関連" 日本衛生学雑誌. 49. 250- (1994)

    • Related Report
      1993 Annual Research Report
  • [Publications] 今井秀樹、厳庫敏、影山隆之、新田裕史、兜真徳: "心臓自律神経系活動性の変動要因について:尿中カテコッレアミン排泄速度との関連" 日本衛生学雑誌. 49. 251- (1994)

    • Related Report
      1993 Annual Research Report

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Published: 1993-04-01   Modified: 2016-04-21  

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