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The effect of gelanicals on viral infectious desease in senium

Research Project

Project/Area Number 05454235
Research Category

Grant-in-Aid for General Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field Public health/Health science
Research InstitutionOsaka Prefectural Institute of Public Health

Principal Investigator

UEBA Noboru  Osaka Prefectural Institute of Public Health, Public Health Department, Division of Pathology, Director, 公衆衛生部・病理課, 課長 (60250297)

Co-Investigator(Kenkyū-buntansha) KAJIMURA Keiji  Osaka Prefectural Institute of Public Health, Researcher, 薬事指導部, 研究員 (40250336)
YAMASAKI Katuhiro  Osaka Prefectura Institute of Public Health, Senior Researcher, 薬事指導部, 主任研究員 (20250334)
TAKAGI Yasuhiro  Osaka Prefectural Institute of Public Health, Senior Researcher, 公衆衛生部・病理課, 主任研究員 (20192148)
MAEDA Akiko  Osaka Prefectura Institute of Public Health, Senior Researcher, 公衆衛生部・ウイルス課, 主任研究員 (40250279)
Project Period (FY) 1993 – 1995
Project Status Completed (Fiscal Year 1995)
Budget Amount *help
¥5,400,000 (Direct Cost: ¥5,400,000)
Fiscal Year 1995: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 1994: ¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 1993: ¥2,000,000 (Direct Cost: ¥2,000,000)
KeywordsAntibody producition / Mouse / Prescribed herbal medicine / Phylaxis / Senile / 高齢期
Research Abstract

Research into the effect of herbal medication on the declined immune system of the old aged was carried out using about 140 different isolated herbal medicines and several types of prescribed Chinese herbal medicine. It was clear that ogi, ginseng, angelica root and about ten other isolated herbal medicines, activated the immune system in the old aged. And of the prescribed Chinese herbal medicine, hochuekki-to, juzentaiho-to, and maobushisaishinn-to had effect. We made an investigation to see if they can actually improve the phylaxis function in the old aged with the viral infection. It was clear that angelica root, ogi and ginseng improved the phylaxis function against infection of Japanese encephalitis virus. Maobushisaishinn-to had effect against infection of influenza virus.

Report

(4 results)
  • 1995 Annual Research Report   Final Research Report Summary
  • 1994 Annual Research Report
  • 1993 Annual Research Report
  • Research Products

    (14 results)

All Other

All Publications (14 results)

  • [Publications] Keiji Kajimura et al: "Pharmacological Quality of Astragali Radix : the Effect on Atibody Production" Natural Medicines. 51. in press (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Keiji KAJIMURA: "Protective Effect Astragali Radix by Oral Administration against Japanese Encephalitis Virus Infeotion in Mice" Biological Pharmaceutical Bulletin. 19. 1166-1169 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Keiji KAJIMURA: "Protective effect of Astragali Radix by intraperitoneal injection against" Biological Pharmaceutical Bulletin. 19. 855-859 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Yasuhiro TAKAGI: "Effect of mao-bushi-saishin-to on the primary antibody response in mice" J.Traditional Medicines. 13. 94-99 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Yasuhiro TAKAGI: "Effect of mao-bushi-saishin-to,a traditional herb medicine,on influenza" Biomedical Gerontology. 19. 120- (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Yasuhiro TAKAGI: "Effect of Three Chinease Harbs on the Primary Immune response in Mice" Proceedings of Osaka Prefectural Institue of Public Health. 33. 83-86 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Yasuhiro TAKAGI,Satoshi ABURADA,Katsuhiro YAMASAKI,Noboru UEBA,Morio YONZAWA and Norio KATOH: "Effect of Angelica acutiloba extract on the Survival Ratio of Mice Inoculated with Japanese Encephalitis Virus" Proceedings of Osaka Prefectural Institute of Public Health, ED of Public Health. 32. 59-62 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Yasuhiro TAKAGI,Noboru UEBA,Natsumi HIGASHI,Yoshiki NUNOURA: "Effect of Three Chinease Harbs on the Primary Immune response in Mice" Proceedings of Osaka Prefectural Institute of Public Health. 33. 83-86 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Yasuhiro TAKAGI,Akiko MAEDA,Noboru UEBA,Natsumi HIGASHI,Hirohiko YAMAMURA,Yoshiki NUNOURA: "Effect of mao-bushi-saishin-to, a traditional herb medicine, on influenza virus infection in aged mouse" Biomedical Gerontology. 19. 120 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Yasuhiro TAKAGI,Akiko MAEDA,Noboru UEBA,Natsumi HIGASHI,Hirohiko YAMAMURA,Yoshiki NUNOURA: "Effect of mao-bushi-saishin-to on the primary antibody response in mice of different ages" J.Traditional Medicines. 13. 94-99 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Keiji KAJIUURA,Yasuhiro TAKAGI,Noboru UEBA,Katsuhiro YAMASAKI,Yoshikazu SAKAGAMI,Hiroshi YOKOYAMA and Kaisuke YONEDA: "Protective Effect of Astragali Radix by Intraperitoneal Injection against Japanese Encephalitis Virus Infection in Mice" Biological Pharmaceutical Bulletin. 19 (9). 855-859 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Keiji KAJIMURA,Yasuhiro TAKAGI,Noboru UEBA,Katsuhiro YAMASAKI,Yoshikazu SAKAGAMI,Hiroshi YOKOYAMA and Kaisuke YONEDA: "Protective Effect of Astragali Radix by Oral Administration against Japanese Encephalitis Virus Infection in Mice" Biological PHarmaceutical Bulletin. 19 (9). 1166-1169 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Keiji KAJIMURA,Yasuhiro TAKAGI,Mayumi MIMURA,Noboru UEBA,Kaitsuhiro YAMASAKI,Yoshikazu SAKAGAMI,Hiroshi YOKOYAMA and Kaisuke YONEDA: "Pharmacological Quality of Astragali Radix : the Effect on Atibody Production in vitro" Natural Medicines. 51 (1) (in press). (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Keiji Kajimura et al: "Protective effect of Astragali Radix by intraperitoneal injection against" Biocogical & Pharmaceutical Bulletin. 19. (1996)

    • Related Report
      1995 Annual Research Report

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Published: 1993-04-01   Modified: 2018-02-02  

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