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Development of monoenergetic energy neutron generating target for irradiation of biological materials using an accelerator and its dosimetry

Research Project

Project/Area Number 05558071
Research Category

Grant-in-Aid for Developmental Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field 環境影響評価(含放射線生物学)
Research InstitutionHIROSHIMA UNIVERSITY

Principal Investigator

HOSHI Masaharu  Research Institute For Radiation Biology and Medicine Professor, 原爆放射能医学研究所, 教授 (50099090)

Co-Investigator(Kenkyū-buntansha) IWAMOTO Eigi  Nissin-High Voltage Co., Ltd., Head of Research, 研究課長
SAKAMOTO Osamu  Nissin-High Voltage Co., Ltd., Chief of Research, 研究主任
HASAI Hiromi  Faculty of Engineering, Professor, 工学部, 教授 (70034337)
Project Period (FY) 1993 – 1994
Project Status Completed (Fiscal Year 1994)
Budget Amount *help
¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 1994: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1993: ¥2,500,000 (Direct Cost: ¥2,500,000)
Keywordsneutron / neutron target / dosimetry / monoenergy neutron / Shenkel type accelerator / biological effects of neutrons / lithium-7
Research Abstract

This study included that (1) development of monoenergetic energy neutron generating system for use in radiobiology study (especially development of neutron generating targets), (2) dosimetry study of the neutrons.
The actual studies were (a) development and confirmation of a technique to evaporate lithium metal on copper plate and to use as thin lithium target of about 10 mum thickness, (b) measurement of neutron dose rate generating due to (n, p) reaction using twin chamber method, (c) measurement of quality and spectra of the neutrons using LET counters and Hc-3 neutron spectrometer, respectively, (d) measurement of stableness of the target (possible irradiation time) and (e) test irradiation of mice to check total irradiation system. As for the measurement (b) we used a tissue equivalent chamber for determination of total neutron plus gamma-ray doses, and graphite chamber and GM counter for determination of gamma-ray dose.
In the study of (a) we used a evaporation apparatus and made about 10mum thick lithium target. Now we can make them routinely. As for (b) we determined dose rates at different angles and distances.The dose rate more than 10 cGy/min is available and contamination of gamma rays are less than 5%. In(c)energy spread of monoenergy neutrons are 5-9%. We found the LET spectrum reproduced the other measurements. In (b), we found irradiation for about 10 hours are possible. In (e), we checked the total irradiation system was working reasonably.
In conclusion we confirmed this neutron irradiation system for radiobiology study and successfully completed this study. After this, it will be neccessary that development of the other types of targets and set up of the PIXE system.

Report

(3 results)
  • 1994 Annual Research Report   Final Research Report Summary
  • 1993 Annual Research Report
  • Research Products

    (17 results)

All Other

All Publications (17 results)

  • [Publications] H.Watanabe: "ffects os dose rate and energy level on fission neutron(^<252>Cf) tumorigenesis in B6C3F1 mice." J. Radiat. Res.34. 235-239 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] M.Hoshi: "Fallout radioactivity in soil and food samples in the Ukraine: Measurements of iodine,plutonium,cesium and strontium isotopes." Health Phys.67. 187-191 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] M.Hoshi: " ^<137>Cs concentration among children in areas contaminated with radioactive fallout from the Chernobyl accident: Mogilev and Gomel blasts,Belarus." Health Phys.67. 272-275 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Tanaka: "Effects of ^<252>Cf neutrons,transmitted through an iron block on human lymphocyte chromosome." Int. J. Radiat. Biol.66. 391-397 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 遠藤 暁: "広島大学原医研の中性子発生装置及び試験実験について" 広島医学. 47. 415-417 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] H.Watanabe et al: "Effects os dose rate and energy level on fission neutron(^<252>Cf)tumorigenesis in B6C3F1 mice" J.Radiat.Res. 34. 235-239 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] M.Hoshi et al: "Fallout radioactivity in soil and food samples in the Ukraine : Measurements of iodine, plutonium, cesium and strontium isotopes" Health Phys. 67. 272-275 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] M.Hoshi et al: "^<137>Cs concentration among children in areas contaminated with radioactive fallout from the Chernobyl accident : Mogilev and Gomel blasts, Belarus" Health Phys. 67. 272-275 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] K.Tanaka et al: "Effects of^<252>Cf neutrons, transmitted through an iron block on human lymphocyte chromosome" Int.J.Radiat.Biol. 66. 391-397 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] S.Endo et al: "Test experiment of the neutron generator at RIRBM" J.Hiroshima Med.Ass. 47. 415-417 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] H.Watanabe: "Effects of doserate and energy level on fission neutron(^<252>cf)tumorigenesis in BGC3F1 mice" J.Radiat.Res.34. 235-239 (1993)

    • Related Report
      1994 Annual Research Report
  • [Publications] M.Hoshi: "Fallont radioactivity in Soil and food samples in the Ukraine:Measurements of iodine,plutonium,cesium,and strontium isotopes" Health Phys.67. 187-191 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] M.Hoshi: "^<137>Cs concentration among children in areas contaminated with Radioactive fallout from the Chernobyl accident:Mogilev and Gromel oblsast,Belarus" Health Phys.67. 272-275 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] K.Tanaka: "Effects of ^<252>cf neutrons,transmitted through an iron block on human lymphocyte chromosome" Jut.J.Radiat.Biol.66. 391-397 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] 遠藤 暁: "広島大学原医研の中性子発生装置及び試験実験について" 広島医学. 47. 415-417 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] H.Watanabe: "Effects of dose roteand energy level on fission neutron ^<252>Cf tumorigenesis in B6C3F1 mice" J.Radiat.Res.34. 235-239 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] M.Hoshi: "Fallout radioactivity in soil and food samples in the Ukraine:Measurements of iodine,plutonium,cesium,and strontium isotopes" Health Phys.66. 1-5 (1994)

    • Related Report
      1993 Annual Research Report

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Published: 1993-04-01   Modified: 2016-04-21  

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