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A participation of the folliculo-stellate cells of the anterior pituitary on the control of secretion.

Research Project

Project/Area Number 05670025
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field General anatomy (including Histology/Embryology)
Research InstitutionNagoya City University

Principal Investigator

SOJI Tsuyoshi  Nagoya City Univ., Med.Sch., The First Dept. of Anatomy, Professor, 医学部, 教授 (50056925)

Co-Investigator(Kenkyū-buntansha) KANAI Miharu  Nagoya City Univ., Med.Sch., The First Dept. of Anatomy, Research Associate, 医学部, 助手 (70094365)
KURONO Chiek  Nagoya City Univ., Med.Sch., The First Dept. of Anatomy, Research Associate, 医学部, 助手 (50080049)
HOTTA Yasuaki  Nagoya City Univ., Med.Sch., The First Dept. of Anatomy, Lecturer, 医学部, 講師 (90117854)
MABUCHI Yoshio  Nagoya City Univ., Med.Sch., The First Dept. of Anatomy, Assistant Professor, 医学部, 助教授 (80106228)
Project Period (FY) 1993 – 1994
Project Status Completed (Fiscal Year 1994)
Budget Amount *help
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1994: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1993: ¥1,600,000 (Direct Cost: ¥1,600,000)
KeywordsRat / Anterior Pituitary Gland / Folliculo-Stellate Cell / Gap Junction / S-100 Protein / Condition of Fixation / Electron Microscope / Rathke's Residual Pouch
Research Abstract

Although there are many concepts about the function of the folliculo-stellate cell in the anterior pituitary, exact functions are still unknown. That is a supporting cell and/or stem cell theory. It is understood that the cell is a silent cell to the experimental conditions. On the other hand, it is not found the innervation to control hormone secretion of the gland. We had shown that the folliculo-stellate cells which consisted the follicle were connected by the gap junctions and also follicles connected by the gap junctions. Thus the folliculo-stellate cells make up the dense network over the gland and the cell behaves as functional syncytium. These findings clearly indicate that the cells directly participates into control the secretion function of the gland. On this view point, we start the studies to clarify following things :
1) Ultrastructural 3-D architecture
2) Distributions of enzymes on the plasma membrane
3) Gap Junctional network of the folliculo-stellate cells
We published papers in attached paper as the results of our studies. And also we send the following papers for publication.
1) In vivo uptake of lecithin-coated polystirene beads by rat hepatocytes and sinusoidal endothelial cells. Miharu Kanai et al. (to the Cell and Tissue Research)
2) Intercellular communications of the developing anterior pituitary of the female rat Chieko Kurono et al. (to the Anatomical Record)
3) Sealing of the follicular lumen of the anterior pituitary of male rat. Yoshio Mabuchi et al. (to the Anatomical Record)

Report

(3 results)
  • 1994 Annual Research Report   Final Research Report Summary
  • 1993 Annual Research Report
  • Research Products

    (23 results)

All Other

All Publications (23 results)

  • [Publications] Soji,T.: "Intercellular communication within the rat anterior pituitary gland.V.Changes in cell-to-cell communications as a function of the timing castration in male rats." Anat.Rec.235. 577-582 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 黒野 智恵子: "電子顕微鏡の前固定におけるpHと浸透圧の影響、特に下垂体前葉に対する影響" 解剖学雑誌. 68(6). 787 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 黒野 智恵子: "ラット下垂体前葉の前固定での浸透圧の影響とそこで観察された“Septate Junction"" 解剖学雑誌. 69(1). 82 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] 馬渕 良生: "ラット下垂体前葉の洞様毛細血管の生後発生" 解剖学雑誌. 69(1). 82 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Soji,T.: "Immunohistochemical study of the post-natal development of the folliculo-stellate cells in the rat anterior pituitary gland." Tissue and Cell. 26(1). 1-8 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Kurono,C.: "Septate-like junctions in the normal male rat pituitary gland." Tissue and Cell. 26(6). 913-916 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Nishizono H,Soji T,Herbert D.C.: "Intercellular communication within the rat anterior pituitary gland : V.Chanes in cell-to-cell communications as a function of the timing of castration in male rats." Anat.Res.235. 577-582 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Nishizono H,Murata Y,Tanaka M,Soji T,Herbert D.C.: "Evidence that Muller cells can Phagocytize egg-lecithin-coated silicone particles." Tissue Cell. 25. 305-310 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Kanai M,Watari N,Soji T,Sugawara E.: "Formation and accumulation of lipolysosomes in developing chick hepatocytes." Cell Tissue Res.275. 125-132 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Soji T,Sirasawa N,Kurono C,Yashiro T.Herbert D.C.: "Immuno-histochemical study of the folliculo-stellate cells in the rat anterior pituitary gland." Tissue Cell. 26. 1-8 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Ohira A,Chihara E,Soji T: "Egress route of emulsified 20 centi-stokes silicone oil from anterior chamber of rabbit." Cur.Eye Res.13. 489-495 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1994 Final Research Report Summary
  • [Publications] Soji,T.: "Intercelular communicaton with the rat anterior pituitary gland.V.Changes in cell-to-cell communications as a function of the ……" Anat,Rec.235. 577-582 (1993)

    • Related Report
      1994 Annual Research Report
  • [Publications] 黒野智恵子: "電子顕微鏡の前固定におけるpHと浸透圧の影響、特に下垂体前葉に対する影響" 解剖学雑誌. 68(6). 787- (1993)

    • Related Report
      1994 Annual Research Report
  • [Publications] 黒野智恵子: "ラット下垂体前葉の前固定での浸透圧の影響とそこで観察された“Septate Junction"" 解剖学雑誌. 69(1). 82- (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] 馬渕良生: "ラット下垂体前葉の洞様毛細血管の生後発生" 解剖学雑誌. 69(1). 82- (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Soji,T.: "Immunohistochemical study of the post-natal development of the folliculo-stellate cells in the rat anterior pituitary gland." Tissue and Cell. 26(1). 1-8 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Kurono,C.: "Septate-like junctions in the normal male rat pituitary gland." Tissue and Cell. 26(6). 913-916 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Soji,T.: "Intercellular communication within the rat anterior pitullary gland.V.Changes in cell-to-cell communication as a function of the…" Anat.Rec.235. 577-582 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Soji,T.: "Immunohistochemical study of the postnatal development of the folli-culo-stellate cells in the rat anterior pituitary gland." Tissue Cell. 55(in press). (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Kurono,C.: "Septate junctions in the normal male rat pituitary gland." Tissue Cell. in press. (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 黒野 智恵子: "電子顕微鏡の前固定におけるpHと浸透圧の影響、特に下垂体前葉に対する影響" 解剖学雑誌. 68(6). 787 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 黒野 智恵子: "ラット下垂体前葉の前固定での浸透圧の影響とそこで観察された“Septate Junction"" 解剖学雑誌. 69(1). 82 (1994)

    • Related Report
      1993 Annual Research Report
  • [Publications] 馬渕 良生: "ラット下垂体前葉の洞様毛細血管の生後発生" 解剖学雑誌. 69(1). 82 (1994)

    • Related Report
      1993 Annual Research Report

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Published: 1993-04-01   Modified: 2016-04-21  

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