| Project/Area Number |
05670064
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
Environmental physiology (including Physical medicine and Nutritional physiology)
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| Research Institution | Kanazawa University |
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Principal Investigator |
SHIDO Osamu Kanazawa University, Sch. of Med., Associate Prof., 医学部, 助教授 (40175386)
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| Co-Investigator(Kenkyū-buntansha) |
TAKAHATA Toshinari Kanazawa Institute of Technology, Associate Prof., 助教授 (90159004)
TANABE Minoru Kanazawa Uuniversity, Sch. of Med., Instructor, 医学部, 助手 (20217110)
SAKURADA Sohtaro Kanazawa University, Sch. of Med., Instructor, 医学部, 助手 (00215691)
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| Project Period (FY) |
1993 – 1994
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| Project Status |
Completed (Fiscal Year 1994)
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| Budget Amount *help |
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1994: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1993: ¥1,400,000 (Direct Cost: ¥1,400,000)
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| Keywords | body temperature regulation / heat stress / training / circadian rhythm / adaptation / 運動 |
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| Research Abstract |
The present study was conducted to examine how daily exercise for several hours at a fixed time modifies the pattern of day-night variations in body core temperature and behavior in rats. Spontaneous wheel running was adopted as a model of exercise to avoid any artificial stress on rats.
1. Male Wistar rats were acclimated to cages with a running wheels. Then, the running time of rats were limited to the first or last 3 or 6 h of the dark phase. After a 2-week activity restriction, the rats were again allowed access to the wheel freely. Wheel revolutions of rats during the period corresponding to the previous running time significantly increased after the activity restriction.
2. Male Wistar rats were kept in cages with a running wheel and allowed access to the wheel for 6 h in the last half of the dark phase. After a 3-week exercise period, they were denied to run in the wheel. Their body core temperature significantly increased for 2-3 hours in the last half of the dark phase.
The results suggest that, in rats, voluntary running limited to a fixed time daily alters the pattern of nycthemeral variations in body core temperature and locomotor activity, i.e., body core temperature and running activity increase during the period when the rats were previously allowed to exercise.
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