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Role of circulatory system in the process of the rat incisor eruption

Research Project

Project/Area Number 05671558
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Functional basic dentistry
Research InstitutionTsurumi University

Principal Investigator

CHIBA Mototsugu  Tsurumi Univ., Dent.Med., Professor, 歯学部, 教授 (30064356)

Co-Investigator(Kenkyū-buntansha) YAMAGUCHI Shizuyo  Tsurumi Univ., Dent.Med., Assistant, 歯学部, 助手 (80191229)
YAMANE Akira  Tsurumi Univ., Dent.Med., Assistant, 歯学部, 助手 (20166763)
KOMATSU Koichiro  Tsurumi Univ., Dent.Med., Lecturer, 歯学部, 講師 (60153665)
OHSHIMA Shigeo  Tsurumi Univ., Dent.Med., Assist Prof., 歯学部, 助教授 (90097311)
Project Period (FY) 1993 – 1995
Project Status Completed (Fiscal Year 1995)
Budget Amount *help
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1995: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1994: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1993: ¥1,500,000 (Direct Cost: ¥1,500,000)
Keywordsrat / incisor / eruption / circulatory system / eruptive force / 萌出過程 / 荷重 / 歯根膜 / クリープ / 萌出運動
Research Abstract

1. A method was established with which the force generated by the erupting rat mandibular incisor could be measured when the tooth is placed in isometric condition under artificial respiration with halothane anaesthesia. This method also enables us to measure the displacement of the tooth under isotonic forces.
2. The maximum pushing forces measured by the erupting incisor were 9.1(]SY.+-。[)2.5 mN in impeded teeth and 9.8(]SY.+-。[)2.3 mN in unimpede teeth when the teeth were placed in isometric condition for 20 hours.
3. The forces generated by the incisor after death of the animals were measured under isometric condition. The retractive forces were 3.7(]SY.+-。[)1.3 mN in impeded teeth and 3.0(]SY.+-。[)1.2 mN in unimpeded teeth. These results suggest that the main eruptive force of the rat incisor was produced by the pressure of the vasculature in the pulp and/or periodontal tissues which will be antagonized by the retractive forces generated by the colloid osmotic pressure of the serum and recoil of the ligament.
4. The incisor showed biphasic displacements following the application of isotonic intrusive or extrusive forces, i.e.the tooth shhowed an initial rapid displacement followed by a continuous slow movement by the force of either direction.
5. Significant correlations were found between the magnitudes of the forces applied to the inicisor and the rates of the tooth displacement.
6. Eruptive forces of the incisor were estimated as the forces needed to stop the eruptive movement from the formulae of the regression lines. They were 5.6(]SY.+-。[)1.1 mN in impeded teeth and 3.0(]SY.+-。[)0.6 mN in unimpeded teeth when intrusive forces were applied, and 7.5(]SY.+-。[)4.4 mN in impeded teeth and 4.2(]SY.+-。[)1.7 mN in unimpered teeth when extrusive forces were applied. These results suggest that eruptive force of the rat mandibular incisor ranges from 3 to 8 mN.

Report

(4 results)
  • 1995 Annual Research Report   Final Research Report Summary
  • 1994 Annual Research Report
  • 1993 Annual Research Report
  • Research Products

    (5 results)

All Other

All Publications (5 results)

  • [Publications] Chiba,M.,Yamaguchi,S.and Komatsu,K: "Measurement of the force needed to restrain eruptive movement of the rat mandibular incisor" Archives of Oral Biololqy. 41. 341-349 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 小松浩一郎、千葉元つぐ: "低引張り速度で得られた咬合および非咬合ラット切歯歯根膜における応力一歪曲線の解析ならびに組織学的観察" 歯科基礎医学会雑誌. 38. 192-202 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Chiba, M., Yamaguchi, S.and Komatsu, K.: "Measurement of the force needed to restrain eruptive movement of the rat mandibular incisor." Archs Oral Biol.41. 341-349 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Komatsu, K.and Chiba, M.: "Analysis of stress-strain curves and histological observations on the periodontal ligament of impeded and unimpeded rat incisors at low velocities of loading." Jpn.J.Oral Biol.38. 192-202 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Chiba M.: "Possible role of the periodontal ligament and vasculature in axial movements of the rat incisor." The Biological Mechanisms of Tooth Eruption,Resorption and Replacement by Implants,edited by Z.Davidovitch. 459-466 (1994)

    • Related Report
      1994 Annual Research Report

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Published: 1993-04-01   Modified: 2016-04-21  

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