| Project/Area Number |
05680638
|
|---|
| Research Category |
Grant-in-Aid for General Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Developmental biology
|
|---|
| Research Institution | KYOTO UNIVERSITY |
|---|
Principal Investigator |
KAGEYAMA Takashi Kyoto Univ., Primate Res.Inst., Associate Professor, 霊長類研究所, 助教授 (20027501)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
ASAOKA Kazuo Kyoto Univ., Primate Res.Inst., Instructor, 霊長類研究所, 助手 (10089138)
YONEZAWA Satoshi Aichi Prefectural Colony, Leader, 発達障害研究所, 所長 (90001867)
|
|---|
| Project Period (FY) |
1993 – 1994
|
| Project Status |
Completed (Fiscal Year 1994)
|
| Budget Amount *help |
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1994: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1993: ¥1,800,000 (Direct Cost: ¥1,800,000)
|
|---|
| Keywords | cathepsin E / procathepsin E / substance P / FGF / tachykinin / development / カテプソンE |
|---|
| Research Abstract |
1. Procathepsin E was detected at high levels in various fetal tissues.
2. Procathepsin E has unique structural and enzymatic features.
3. Cathepsin E hydrolyzed various biologically active peptides, such as substance P,neurokinin A,and FGF fragments, at around pH 5.
|
