| Project/Area Number |
05807035
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
Public health/Health science
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| Research Institution | Wakayama Medical University |
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Principal Investigator |
HASHIMOTO Tsutomu Professor, Wakayama Medical College, 医学部, 教授 (70118454)
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| Co-Investigator(Kenkyū-buntansha) |
MORIOKA Seiji Assistant, Wakayama Medical College, 医学部, 助手 (70244754)
YOSHIMURA Noriko Assistant, Wakayama Medical College, 医学部, 助手 (60240355)
KASAMATSU Takahiro Lecturer, Wakayama Medical College, 医学部, 助教授 (20073695)
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| Project Period (FY) |
1993 – 1994
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| Project Status |
Completed (Fiscal Year 1995)
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| Budget Amount *help |
¥1,700,000 (Direct Cost: ¥1,700,000)
Fiscal Year 1994: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1993: ¥1,200,000 (Direct Cost: ¥1,200,000)
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| Keywords | cohort study / osteoporosis / bone mineral density / DEXA / bone marker / life style / exercising habit |
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| Research Abstract |
An epidemiologic approach is very informative for the study of any chronic degenerative disease, including osteoporosis. The cohort study is indispensable to clarify the risk factors developing osteoporosis. We set the cohort in Miyama Village, Wakayama Prefecture, as two large national projects on cancer and circulatory diseases. Information on exposure to possible risk factors were collected through a self-administered questionnaire. Once a year, they received health check up examinations in relation to cancer and circulatory diseases.
A list of inhabitants aged 40 to 79 years in the village was compiled based upon resident registration as of December 1988,1543 inhabitants consisting of 716 males and 827 females were identified. As the subset of this cohort, 50 males and 50 females in each of four age strata (40-49,50-59,60-69,70-79) totaling 400 individual were selected randomly. Bone mineral density was measured using dual energy absorptiometry (DEXA). Routine two-dimensional radiographs are also being performed.cord linkage system was established among these information. Based on follow-up study if this cohort, association between osteoporosis and other risk gactors will be analyzed in the future.
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