| Co-Investigator(Kenkyū-buntansha) |
HELGA Siegl Instructor, Center for Biomedical Research, University of Vienna, 医科学研究所, 助手
GEORG Wieselthaler Instructor, Faculty of Medicine, University of Vienna, 医学部, 助手
CHRISTIAN Schmidt Instructor, Faculty of Medicine, University of Vienna, 医学部, 助手
ROLF MULLER・ ウイーン大学, 医学部, 助手
REINALD Seit ウイーン大学, 医学部, 助手
ANTON Moritz Associate Professor, Faculty of Medicine, University of Vienna, 医学部, 助教授
HEINRICH Schima Lecturer, Faculty of Medicine, University of Vienna, 医学部, 講師
HERWIG Thoma Professor, Institute for Biomedical Engineering and Physics, University of Vienn, 医用工学研究所, 教授
UDO Losert Professor, Center for Biomedical Research, University of Vienna, 医科学研究所, 教授
ERNST Wolner ウイーン大学, 医学部, 教授
IMANISHI Kaoru Lecturer, Tokyo Women's Medical College Daini Hospital, 講師 (70168516)
MATSUURA Hiroyuki Instructor, Research Center for Advanced Science and Technology, The University, 先端科学技術研究センター, 助手 (30262116)
ABE Yusuke Instructor, Faculty of Medicine, The University of Tokyo, 医学部, 助手 (90193010)
CHINZEI Tsuneo Instructor, Faculty of Medicine, The University of Tokyo, 医学部, 助手 (20197643)
MABUCHI Kunihiko Associate Professor, Research Center for Advanced Science and Technology, The Un, 先端科学技術研究センター, 助教授 (50192349)
BABA Kazunori Associate Professor, Faculty of Medicine, The University of Tokyo, 医学部, 助教授 (30181035)
FUJIMASA Iwao Professor, Research Center for Advanced Science and Technology, The University o, 先端科学技術研究センター, 教授 (30010028)
WOINER Ernst Professor, Faculty of Medicine, University of Vienna
ROLF Muller Michael Instructor, Faculty of Medicine, University of Vienna
REINALD Seitelberger Instructor, Faculty of Medicine, University of Vienna
MICHAEL Rolf ウィーン大学, 医学部, 助手
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| Budget Amount *help |
¥10,600,000 (Direct Cost: ¥10,600,000)
Fiscal Year 1995: ¥4,800,000 (Direct Cost: ¥4,800,000)
Fiscal Year 1994: ¥5,800,000 (Direct Cost: ¥5,800,000)
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| Research Abstract |
The great numbers of residual problems in artificial heart disturb its longterm clinical use. We, University of Tokyo and Wien University, had cooperated for the past 2 years about the basic problems in the artificial heart. The objectives of our cooperation in this project is to solve many problems disturbing the longterm clinical application of total artificial heart and cardiac assist. In this final year, the following results have been accomplished by our cooperation.
1. The anatomical fittness, blood compatibility, material and its molding method of undulation pumped TAH and flow transformed pulsatile TAH that were developing in University Tokyo were discussed.
2. As for MAD (Modified Assist Device) that was developing in University Tokyo and could be approached transcutaneously, we exchanged opinions from the view point of clinical use.
3. We discussed about 1/R control method that was a quite new control method of TAH and could survive a TAH goat more than 500 days in University of
… More
Tokyo. Especially, they interested in the mechanism of the method, its possibility to use clinically and its application to implantable centrifugal pump that was developing in Wien University.
4. Concernig to the blood compatibility of the materials used in the artificial heart, the data used in the longest survival goat was discussed especially about the cause of carcification generated on the Jellyfish valves.
5. We discussed about how to evaluate hemody namics and microcirculation during the artificial heart pumping. Implantable apparatus to observe the microcirculation using CCD and cathecolamine sensor that were developed in University of Tokyo were also discussed.
6. Blood compatibility, performance and control method of implantable centrifugal blood pump that have been developing in Wien University were discussed.
7. As a bridge patient were in the University hospital at that time, we could get many informations of performance, blood compatibility, safety and reliability of the clinical use of Novacor implantable left ventricular assist device as the bridge to the heart transplntation.
These results were reported at 22nd Annual Meeting of European Society for Artificial Organs, 10th Biannual Conference of International Society for Artificial Organs and other domestic conferences. Less
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