Epidemiological Investigation on Environmental Pollution

Research Project

Project/Area Number	06044209
Research Category	Grant-in-Aid for international Scientific Research
Allocation Type	Single-year Grants
Section	Joint Research
Research Institution	Aichi-Gakuin University
Principal Investigator	NATSUME Nagato 2nd Dept. of Oral and Maxillofacial Surgery, Aichi-Gakuin University, 歯学部・口腔外科学第二講座, 講師 (90183532)
Co-Investigator(Kenkyū-buntansha)	DANIEL Lew アイオワ大学, 口腔外科, 教授閔丙一ソウル大学, 口腔外科学, 教授 NGUYENTHI DU ホーチミン市立口腔病院, 医師 NGUYENTHI NG ツーヅー病院, 院長 SUZUMORI Kaoru Nagoya City University Hospital, 医学部・産科婦人科, 助教授 (80117829) YAMADA Morimasa Fujita Health University, 医学部・麻酔科, 講師 KATSUKI Takeshi Dept. of Oral and Maxillofacial Surgery Saga Medical School, 口腔外科学, 教授 (70038868) YAMANAKA Katsumi Nagoya Health Research Institute, 所長 SHIOTA Kouhei Faculty of Medicine, Kyoto University, 医学部, 教授 (80109529) KAWAI Tsuyoshi 2nd Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Aichi-Gakuin U, 歯学部・口腔外科学第二講座, 教授 (50064788) LEW Dainiel University of Iowa Hospitals and Clinics MIN. Byong-il CHONG-A.DENTAL HOSPITAL DUC TIN Nguyen Thi Cnetre D'odonto Maxillo Facial HCM Ville NGOC PHUONG Nguen Thi Tu Du Obstetrical and Gynaecological Hospital NGUYEN THI D ホーチミン市立口腔病院, 医師 LE HUYNH ベンチェ省人民委員会国際援助管理局長, 児童保護育成委員会, 副知事委員長 NGUYEN THI N ツーヅー病院, 院長山中克己名古屋市立衛生研究所, 所長
Project Period (FY)	1994 – 1995
Project Status	Completed (Fiscal Year 1995)
Budget Amount *help	¥3,900,000 (Direct Cost: ¥3,900,000) Fiscal Year 1995: ¥1,400,000 (Direct Cost: ¥1,400,000) Fiscal Year 1994: ¥2,500,000 (Direct Cost: ¥2,500,000)
Keywords	Cleft Lip / Cleft Palate / Congenital Anomalies / Orangeade / Medical Support / Vietnam / Genetic Analysis
Research Abstract	We collected the blood sample from both Cleft Lip and/or Palate patients and parents while we stayd at Ben Tre, Vietnam, between December 8 and 26 in 1995. The results was as follws : In the province of Ben Tre where we investigated, 252 children were identified as cleft lip and/or palate patients among 169,467 whose ages are between 0 and 5.Comparing with the tendency of incidence of Japanese, there was no disinguished differences. We have been analyzing the blood sampls of families as well as patients with Cleft Lip and/or Palate themselves genetically. At the moment, no significant differences have not been appeared comparing with any other races. There was no evidence found that the orangeade caused the frequent incidence of cleft lip and/or palate. We could not find out any characterisitic features and/or change on the gene, caused by orangeade such as dioxin.