有機硫黄化学の基礎および応用的研究

• Project/Area Number: 06353003
• Research Category: Grant-in-Aid for Co-operative Research (B)
• Allocation Type: Single-year Grants
• Research Field: Organic chemistry
• Research Institution: The University of Tokyo
• Principal Investigator: 岡崎 廉治 東京大学, 大学院・理学系研究科, 教授 (70011567)
• Co-Investigator(Kenkyū-buntansha): 古川 尚道 筑波大学, 化学系, 教授 (80015966) ; 園田 昇 大阪大学, 工学部, 教授 (20083983) ; 小倉 克之 千葉大学, 工学部, 教授 (60114253) ; 秋葉 欣哉 広島大学, 理学部, 教授 (20011538) ; 安藤 亘 筑波大学, 化学系, 教授 (30008429)
• Project Period (FY): 1994
• Project Status: Completed (Fiscal Year 1994)
• Budget Amount: ¥2,900,000 (Direct Cost: ¥2,900,000); Fiscal Year 1994: ¥2,900,000 (Direct Cost: ¥2,900,000)
• Keywords: 硫黄 / 医薬 / 生理活性物質 / 機能性物質 / 有機電導体

Research Abstract

本研究は,1996年に日本において開催の予定されている第17回有機硫黄化学国際シンポジウムを最大限実りのあるものとするため,国内の当該分野における多方面の研究者を組織し,研究内容の面からの企画を行うことを目的として行われた。
有機硫黄化学国際シンポジウムは,1964年にその第1回が開催され,有機硫黄化学の分野の唯一の国際会議として,その分野の発表に大きな貢献をしてきた。第15回シンポジウムはフランスのカーンで1992年に開かれ,第16回シンポジウムは1994年7月ドイツのメルゼブルクで開かれた。本総合研究は,第16回シンポジウム終了後直ちに日本での開催に向けて,以下のような企画調査を行った。
有機硫黄化学の研究範囲は近年とみに急速な拡大を見せ基礎的側面から,材料への応用,工業的応用,医薬・農薬への応用などに到るまで広範囲に及ぶ。そこで,まず基礎,応用それぞれの分野での研究者が研究連絡会を行い,それぞれに現状を整理し,将来への発展の糸口を探った。その後基礎,応用分野における研究連絡会での討論を基に,両分野の研究者が集合し,全体研究連絡会議を行い,国際会議開催のかめのテーマ選択を行った。また,有機硫黄・リン化合物討論会が発展して作られたヘテロ原子化学討論会で,研究班員が発表を行い,情報を交換した。さらに3回の幹事会も行った。

Research Products

• [Publications] H.Suzuki: "The First Genuine Silicon-Sulfur Double-Bond Compound:Synthesis and Crystal Structure of a Kinetically Stabilized Silanethione" J.Am.Chem.Soc.116. 11578-11579 (1994)
• [Publications] K.Ohkata: "Methylation of Tetrazathiopentalenes(10-S-3 Sulfurane)Fused with Pyridine and/or Pyrimidine Rings and Ristricted Rotation of the Pyrimidine Ring:Chemical Evidences for N-S-N Hypervalent Bond" Heterocycles. 38. 1707-1710 (1994)
• [Publications] F.Hojo: "Photochemical Reactions of Polysilacycloalka-1,2-dienes:Synthesis of Polysila 1,3-Bridged Cyclopropenes" Organometallics. 13. 3402-3404 (1994)
• [Publications] S.Hashimoto: "Enantioselective Intramolecular C-H Insertions of a-Diazo B-Keto Esters Catalyzed.by Dirhodium(II)Tetrakis〔N-phthaloyl-(S)-phenylalaninate〕:The Effects of the Substituent at the Insertion Site on Enantioselectivity" Synlett.353-355 (1994)
• [Publications] Y.Niahibayashi: "Syntheses and Reactivities of Ferrocenyl Organyl Tellurides" J.Organometal.Chem.473. 205-213 (1994)
• [Publications] A.Ohno: "NAD(P)^+/NAD(P)H Models.83.Molecular Asymmetry with a Carbonyl Group:Electronically.Controlled Stereochemistry in the Reaction of NAD(P)^+/NAD(P)H Analogs" J.Am.Chem.Soc.116. 8133-8137 (1994)
• [Publications] T.Okuyama: "On the Mechanism of Acid-Catalyzed Hydrolysis of Sulfinate Esters. Oxygen Isotope Exchange and Theoretical Studies" J.Chem.Soc.,Perkin Trans.2. 1011-1014 (1994)
• [Publications] K.Ogura: "High Electron-Acceptability of a 2,2-Bis(alkyl- or arylsulfonyl)-ethenyl Group" Tetrahedron Lett.34. 2649-2652 (1994)
• [Publications] S.Yoshida: "Movel Electron Acceptors Bearing a Heteroquinonoid System.4.Syntheses,Properties,and Charge-Transfer Complexes of 2,7-Bis(dicyanomethylene)2,7-dihydrobenzo〔2,1-b:3,4-b′〕dithiophene,2,7-Bis(dicyanomethylene)-2,7-dihydre-benzo〔1,2-b:4,3-b′〕dithiophene.and 2,6-Bis(dicyanomethyiene)-2,6-dihydrobenzo〔1,2-b:3,4-b′〕dithiophene" J.0rg.Chem.59. 3077-3081 (1994)
• [Publications] N.Ono: "Synthesis of Pyrroles Annulated with Polycyclic Aromatic Compounds;Precursor Molecules for Low Band Gap Polymers" J.Chem.Soc.,Chem.Commun. 1019-1020 (1994)
• [Publications] T.Iwamura: "Novel Benzoyl Migration of the Intermediary 1:1 Adducts of 1,3-Dipolar Cycloaddition of Thiazolo〔3,2-b〕〔1,2,4〕triazolium N-Phenacylides with Dimethyl Acetylene-di-carboxylate" Tetrahedron Lett.35. 4587-4590 (1994)
• [Publications] H.Kageyama: "Tautomeric Equiliblium Between Selenol and Selenoxo Forms of Selenocarboxylic Acids" J.Am.Chem.Soc.116. 2195-2196 (1994)
• [Publications] S.Ryo: "Periselective Intramolecular Cycloaddition of Allenyl Thioethers and Allenyl Sulfones" J.Org.Chem.59. 1621-1632 (1994)
• [Publications] H.Taka: "Synthesis and Stereochemistry of Optically Active Selenonium Imides" J.Chem.Soc.,Perkin Trans. 1. 2257-2264 (1994)
• [Publications] T.Takahashi: "Optically Pure Haloselenuranes.First Synthesis and Nucleophilic Substitutions" J.Org.Chem.59. 3262-3264 (1994)
• [Publications] N.Hayashi: "Channel-to-Channel Rearrangements of Host Lattices in Clathrate Crystals Induced by Guest Exchange via Gas-Solid Contacts" Advanced Materials. 6. 654-656 (1994)
• [Publications] H.Yamachi: "Structural Aspects of the Ambient Presure BEDT-TTF Superconductors" J.Am.Chem.Soc.115. 11319-11327 (1993)
• [Publications] S.Ogawa: "Preparation and Novel One-electron Redox Reactions of a New Stable 4.7-Diisopropyl-W benzol〔1,2-d〕〔1,2,3〕triselenole and its Radical Cation Salt" J.Chem.Soc.,Chem.Commun.1593-1594 (1994)
• [Publications] A.Kato: "A Novel Metallacycle,1,2,5,3-Cobaltadithiazole,Formation,Structure,and Properties of(η^5-Cyclopentadienyl of Pentamethylcyclopentadienyl)(1-phenyl-methanimine-N,1-dithiolato)cobalt(III)" J.Organomet.Chem.473. 313-321 (1994)
• [Publications] T.Inoue: "Syntheses of Thiol,Selenol,and Tellurol Esters from Aldehydes by the Reaction with iBu_2AlYR(Y=S,Se,Te)" J.Org.Chem.59. 5824-5827 (1994)
• [Publications] T.Oikawa: "Syntheses and Properties of 5-Substituted [n](2,4)Pyridinophanes,Madel Compounds of NAN(P)" J.Org.Chem.58. 2046-2051 (1994)
• [Publications] N.Tokitoh: "Synthesis and Structure of 2,4,6-Tris〔bis(trimethylsilyl)methy〕thiobenzaldehyde:The First Isolation of Rotational Isomers of Thioaldehydes" J.Am.Chem.Soc.116. 7907-7908 (1994)
• [Publications] A.Ishii: "The First Isolable Dithirane by Oxidation of a Dithietane" Angew.Chem..Int.Ed.33. 777-779 (1994)
• [Publications] N.Furukawa: "The Simple Preparation of Aldehydes and Ketones by the Photo-Oxygen Rearrangement of Naphtho[1,8-de]dithiin Monooxides" Chem.Lett.1007-1010 (1994)