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Development of automated analytical apparatus for measuring positive/passive smokers' urinary cotinine -Practical application for biological-monitoring and health-education-

Research Project

Project/Area Number 06557032
Research Category

Grant-in-Aid for Developmental Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field Public health/Health science
Research InstitutionKAGAWA MEDICAL SCHOOL

Principal Investigator

JITSUNARI Fumihiko  KAGAWA MEDICAL SCHOOL,DEPARTMENT OF HYGIENE/PUBLIC HEALTH,PROFESSOR, 医学部, 教授 (60127561)

Co-Investigator(Kenkyū-buntansha) GODA Keiko  KAGAWA MEDICAL SCHOOL,DEPARTMENT OF HYGIENE/PUBLIC HEALTH,RESEARCH ASSISTANT, 医学部, 助手 (60263894)
SUNA Shigeru  KAGAWA MEDICAL SCHOOL,DEPARTMENT OF HYGIENE/PUBLIC HEALTH,RESEARCH ASSISTANT, 医学部, 助手 (40253265)
MANABE Yoshiki  KAGAWA MEDICAL SCHOOL,DEPARTMENT OF HYGIENE/PUBLIC HEALTH,RESEARCH ASSISTANT, 医学部, 助手 (40181812)
TAKEDA Noriaki  KAGAWA MEDICAL SCHOOL,DEPARTMENT OF HYGIENE/PUBLIC HEALTH,ASSISTANT PROFESSOR, 医学部, 講師 (40274279)
Project Period (FY) 1994 – 1995
Project Status Completed (Fiscal Year 1995)
Budget Amount *help
¥6,900,000 (Direct Cost: ¥6,900,000)
Fiscal Year 1995: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1994: ¥5,900,000 (Direct Cost: ¥5,900,000)
KeywordsPOSITIVE / PASSIVE SMOKERS / URINARY COTININE / BIOLOGICAL MONITORING / SEMI-AUTOMATED ANALYTICAL APPARATUS FOR MEASURING COTININE / 自動分析装置 / オートマチック リキット ハンドラ-
Research Abstract

Modified glass-chamber methods for measuring urinary cotinine, we developed the semi-automated analytical apparatus composed of 4 compartment (Com), i.g., preparing Com, selection Com, concentrating Com and sample conditioning Com, respectively. Using these apparatus, 60 samples were analyzed all together in a short time with high recovery (recovery rate 84-97%) and low C.V.% (6.7%, by urinary cotinine concentration of 300ng/ml, n=5). Using this apparatus, we obtained the suggestive results about the biological monitoring and health education by cotinine.

Report

(2 results)
  • 1995 Annual Research Report   Final Research Report Summary
  • Research Products

    (25 results)

All Other

All Publications (25 results)

  • [Publications] 武田 則昭: "某事業所における禁煙教育とその評価法に関する検討" 第4回ニコチン依存研究会記録集. 4. 29-32 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] N.Takeda: "URINE CONTININE CONCENTRATIONS OF POSITIVE AND PASSIVE SMOKER IN THE SAME OFFICE BY ION PAIR REVERSED-PHASE HIGH PERFOMANCE LIQUID CHROMATOGRAPHY" PROCEEDINGS OF THE THIRD ASIA-PACIFIC CONFERENCE ON TOBACCO OR HEALTH. 274-279 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 武田 則昭: "職域集団における尿中ニコチン濃度測定とその禁煙教育への応用-短期間での検討-" 四国公衆衛生学会雑誌. 41. 229-237 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 武田 則昭: "人工気象室における紙巻きタバコ燃焼と非喫煙者の暴露前後の尿・唾液中コチニン濃度に関する研究" 四国公衆衛生学会雑誌. 41. 218-228 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 武田 則昭: "青年男子における喫煙者,非喫煙者の尿中コチニン濃度の日差についての検討" 第5回ニコチン依存研究会記録集. 5. 30-33 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 實成 文彦: "タバコ問題の疫学と予防-今日的課題と予防対策-" 第5回ニコチン依存研究会記録集. 5. 13-19 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] N.Takeda: "A Study on Urine Cotinine for the Evaluation of Smoking Lessation" Jpn.J.Hyg.50. 637-651 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] S.Muramatsu: "Relationship Between Urimary Cotinine Levels of Schoolchildren and Their Firental Smoking Hobits" Bull.Natl,Inst.Public Health. 45. 416-423 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 實成 文彦: "タバコ関連問題の疫学と予防" 臨床精神医学. 24. 1159-1174 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] N.Takeda, et.al.: "Smoking cessation education and the evaluation in an office (in Japanese)" Proceedings of Nicotine dependence Association. vol 4. 29-32 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] N.Takeda, et.al.: "URINE COTININE CONCENTRATIONS OF POSITIVE AND PASSIVE SMOKER IN THE SAME OFFICE BY ION PAIR REVERSED-PHASE HIGH PERFOMANCE LIQUID CHROMATOGRAPHY" PROCEEDINGS OF THE THIRD ASIA-PACIFIC CONFERENCE ON TOBACCO OR HEALTH. 274-279 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] N.Takeda, et.al.: "Measurement of urinary cotinine in office workers, and its application for smoking-cessation education (in Japanese)" Shikoku.J.P.H. Vol 40. 229-237 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] N.Takeda, et.al.: "A study on urine/saliva cotinine concentrations of non-smokers exposed by cigarette smoke in an artificial meteorological room (in Japanese)" Shikoku J.P.H. Vol 40. 218-228 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] N.Takeda, et.al.: "Daily variation on urinary cotinine concentration among adult male of smokers/non-smokers (in Japanese)" Proceedings of Nicotine dependence Association. vol 5. 30-33 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] F.Jitsunari, et.al.: "Epidemiology and prevention on tobacco related problems (in Japanese)" Proceedings of Nicotine dependence Association. vol 5. 13-19 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] N.Takeda, et.al.: "A study on Urine Cotinine for the Evaluation of Smoking cessation" Jpn.J.Hyg.vol 50. 637-651 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] S.Muramatsu, et.al.: "Relationship Between Urinary Cotinine Levels of Schoolchildren and Their Parental Smoking Habits" Bull.Natl.Inst.Public Health. vol 45. 416-423 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] F.Jitsunari, et.al.: "Epidemiology and prevention on tobacco related affairs (in Japanese)" Rinshoseishinigaku. vol 24. 1159-1174 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 武田則昭,實成文彦 他: "URINE COTININE CONCENTRATION OF POSITIVE AND PASSIVE SMOKERS IN THE SAME OFFICE BY ION PAIR REVERSED-PHASE HGH PERFOMANCE LIQUID CHROMATOGRAPHY" PROCEEDINGS OF THE THIRD ASIA-PACIFIC CONFERENCE ON TOBACCO OR HEACTH(SMOKE FREE WORLD FOR CHILDREN). 1994. 274-279

    • Related Report
      1995 Annual Research Report
  • [Publications] 武田則昭,實成文彦 他: "禁煙教育の実践とその評価および効果に関する検討" 日本公衆衛生雑誌(特附). 41. 307- (1994)

    • Related Report
      1995 Annual Research Report
  • [Publications] 武田則昭,實成文彦 他: "職域集団における尿中コチニン測定とその禁煙教育への応用-短期間での検討-" 四国公衆衛生学会学会雑誌. 40. 229-237 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 武田則昭,實成文彦 他: "A study on urine cotinine for the evalution of smoking cessation" 日本衛生学雑誌. 50. 637-357 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 實成文彦,武田則昭 他: "タバコ関連問題の疫学と予防" 臨床精神医学. 24. 1159-1174 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 武田則昭,實成文彦 他: "非喫煙者(成人)における尿中コチニン濃度の日差に関する検討" 産業衛生学雑誌. 37. 293- (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 武田則昭,實成文彦 他: "喫煙者(成人)における尿中コチニン濃度の日差に関する検討" 日本衛生学雑誌. 50. 398 (1995)

    • Related Report
      1995 Annual Research Report

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Published: 1994-04-01   Modified: 2016-04-21  

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