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Portable bioelectrical measurement system for longitudinal developmental study of nervous system functions in infants.

Research Project

Project/Area Number 06558006
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section試験
Research Field 体育学
Research InstitutionThe University of Tokyo

Principal Investigator

MIYASHITA Mitsumasa  The University of Tokyo, Graduate school of education, Professor, 大学院・教育学研究科, 教授 (80023571)

Co-Investigator(Kenkyū-buntansha) KOICHI Masaharu  Business office of Hongo, Nihon Kohden Tokyo, Corporation.Chief, 本郷第二営業所, 所長
YAMAMOTO Yoshiharu  The University of Tokyo, Graduate school of education, Professor, 大学院・教育学研究科, 助教授 (60251427)
Project Period (FY) 1994 – 1996
Project Status Completed (Fiscal Year 1996)
Budget Amount *help
¥4,700,000 (Direct Cost: ¥4,700,000)
Fiscal Year 1996: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1995: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 1994: ¥3,000,000 (Direct Cost: ¥3,000,000)
KeywordsDigital Audio Tape / portable bioelectrical measurement system / infants / reciprocal excitation / heart rate variability / 拮抗筋抑制 / 拮抗抑制
Research Abstract

We developed a portable bioelectrical measurement system which consists of a DAT (Digital Audio Tape) recorder and a small bio-amplifier to study the development of nervous system functions in infants.
We first investigated the longitudinal development of reciprocal innervation to examine developmental changes in human motor nervous system. The "radiated" stretch reflex to antagonist muscle in infants and adults, termed "reciprocal excitation", was evaluated. The phasic stretch reflex and the reciprocal excitation were evoked by the Achilles tendon tapping. The surface electromyogram was recorded in the soleus and the tibialis anterior. The reciprocal excitation increased at around the developmental stage of acquisition of standing, and decreased after the acquisition of walking. It was suggested that the spinal neural pathway of reciprocal innervation changed dramatically at these stages of motor development and these changes were related to the acquisition of movements.
We next investi … More gated longitudinal changes in the autonomic nervous system activities during the first year of life. Beat-to-beat heart rate variability (HRV ; 600 beats) was recorded from 6 healthy infants (5 males, 1female). HRV data were analyzed by coarse graining spectral analysis to break down their total power (TOT) into harmonic and nonharmonic (fractal) components. The harmonic component was further divided into low (0.0-0.15Hz ; LF)and high (>0.15Hz ; HF)frequency components. The sympathetic (SNS) and parasympathetic (PNS) nervous system activities were evaluated from log (LF/HF) and log (HF/TOT), respectively. The fractal component has the spectrum of 1/f^<beta> and the spectral exponent beta was calculated. There was no consistent pattern of development for SNS and PNS activity indicators among individuals. Spectral exponent beta was, however, negatively correlated (P<0.05)with postnatal age for 4 infants and it tended to decrease rapidly after about 240th day of life. These results indicated that the complexity of HRV increased during postnatal life. Less

Report

(4 results)
  • 1996 Annual Research Report   Final Research Report Summary
  • 1995 Annual Research Report
  • 1994 Annual Research Report
  • Research Products

    (11 results)

All Other

All Publications (11 results)

  • [Publications] 北城圭一, 山本義春, 宮下充正: "ヒト運動神経系の拮抗筋抑制システムの発達過程" 第11回生体・生理工学シンポジウム論文集. 357-360 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] K.Kitajo, Y.Yamamoto and M.Miyashita: "Development of control system of antagonist muscles in human motor nervous system." Proceedings of the 11th Symposium on Biological and Physiological Engineering. 357-360 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 北城圭一、山本義春、宮下充正: "ヒト運動神経系の拮抗筋制御システムの発達過程" 第11回生体・生理工学シンポジウム論文集. 357-360 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 福崎千穂、宮下充正: "乳幼児の運動生理" 臨床スポーツ医学. 12. 253-257 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 宮下充正: "運動するから健康である" 東京大学出版会, 143 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Yamamoto,Y.and R.L.Hughson: "On the fractal nature of heat rate variability in humans:effects of data length and β-adrenergic blockade." American Journal of Physiology(Regulatory Integrative Comp.Physiol.35). 266. R40-R49 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Butler,G.C. Y.Yamamoto and R.L.Hughson: "Fractral nature of short-term systolic BP and HR variability during lower body negative pressure." American Journal of Physiology(Regulatory Integrative Comp.Physiol.35). 267. R26-R33 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Butler,G.C. Y.Yamamoto and R.L.Hughson: "Heart rate variability to monitor autonomic nervous system activity during orthostatic stress." Journal of Clinical Pharmacology. 34. 558-562 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] Nakazawa,K. K.Masani M.Miyashita and H.Yano: "EMG activities of mono-and bi-articular muscles during goal-directed ballistic movement." Human Movement Science. 13. 601-610 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] 野崎大地,山本義春: "生体のI/f^β ゆらぎとその解析法" BME. 8(10). 5-12 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] 北城圭一,白山正人,宮下充正: "ニューラルネットワークによる等尺性随意膝伸展筋力発揮時のEMG-トルク関係の学習" Japanese Journal of Sports Sciences. 14(2),(印刷中). (1995)

    • Related Report
      1994 Annual Research Report

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Published: 1994-04-01   Modified: 2016-04-21  

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