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STUDY ON THE REALIZATION OF A COMPACT PROTON ACCELERATOR FOR CANCER THERAPY

Research Project

Project/Area Number 06559011
Research Category

Grant-in-Aid for Developmental Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field 広領域
Research InstitutionKYOTO UNIVERSITY

Principal Investigator

NODA Akira  KYOTO UNIVERSITY,Institute for Chemical Research, Professor, 化学研究所, 教授 (20114605)

Co-Investigator(Kenkyū-buntansha) HIROTA Junichi  HITACHI WORKS,HITACHILTD.CHIEF ENGINEER, 日立工場, 主任技師
HIRAMOTO Kazuo  HITACHI RESEARCH LABORATORY.HITACHI LTD.CHIEF RESEARCHER, 日立研究所, 主任研究員
SHIRAI Toshiyuki  KYOTO UNIVERSITY,Institute for Chemical Research, INSTRUCTOR, 化学研究所, 助手 (50252507)
IWASHITA Yoshihisa  KYOTO UNIVERSITY,Institute for Chemical Research, INSTRUCTOR, 化学研究所, 助手 (00144387)
INOUE Makoto  KYOTO UNIVERSITY,Institute for Chemical Research, Professor, 化学研究所, 教授 (90028176)
Project Period (FY) 1994 – 1995
Project Status Completed (Fiscal Year 1995)
Budget Amount *help
¥17,500,000 (Direct Cost: ¥17,500,000)
Fiscal Year 1995: ¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 1994: ¥14,500,000 (Direct Cost: ¥14,500,000)
KeywordsProton Cancer Therapy / Combined-function Synchrotron / Resonant Beam Extraction / Synchronization with Breezing / Compact Gantry / Untuned RF Acceleration Cavity / Multi-feed Coupling / Digital Synthesizer / 陽子シンクロトロン / ラティス設計 / シンクロトロン加速 / 周波数制御 / 非同調型高周波加速空胴 / 半導体増幅器 / がん治療専用小型陽子加速器
Research Abstract

Radiation cancer therapy is noteworthy from the point of view of quality of life of the patients because of the merit of keeping the function of the body. Especially proton therapy has become important because it is equivalent to the X ray in the biological effect and tremendous amount of experience of treatment with X ray can be effectively utilized in addition to the fact that it can localize the radiation dose to the affected part. In the present study, we have developed a compact proton accelerator for cancer therapy in order to enable wide spread use of proton therapy.
In detail, the following studies have been advanced priented for proton synchrotron which can be easily operated with various energies.
1.Combined-function lattice is adopted for the merit of compactness and eazy operation. As the slow beam extraction method, we have adopted the new scheme to apply a transverse RF electric field keeping the betatron tune to be constant, which is suitable for the synchronization of the … More beam irradiation with breathing of the patient.
2.After the reduction of the required acceleration voltage by optimization of the acceleration pattern, we have adopted an untuned RF accelerating cavity, which avoided the complicated tuning of the RF cavity. By invention of a new power feeding method called multi-feed coupling, efficiency of utilization of the applied RF power has been largely improved by the reduction of reflection power. An RF acceleration cavity applicable to a real proton synchrotron dedicated for cancer therapy has been completed with the untuned type excited by a 2kW solid state amplifier. By the high power test, it is found to be well put to practical use from the points of view of generated gap-voltage, necessary input power and its temperature rise.
3.An RF control device fabricated on the boards of the personal computer has been developed adopting a digital synthesizer with good purity of frequency. With use of this devive, feed back control with beam position and phase error is considered to become unnecessary if the step frequency control according to the change of the magnetic field is precise enough. Thus the daily routine operation of the synchrotron is expected to be possible. Less

Report

(3 results)
  • 1995 Annual Research Report   Final Research Report Summary
  • 1994 Annual Research Report
  • Research Products

    (29 results)

All Other

All Publications (29 results)

  • [Publications] Akira Noda et al.,: "Dedicated Accelerator Project for Proton Therapy at Kyoto University" Proceedings of NIRS International Seminar on the Application of Heavy Ion Accelerator to Radiation Therapy of Cancer in connection with XXI PTCOG Meeting. 292-294 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Kazuo Hiramoto et al.,: "A Compact Proton Synchrotron with a Combined Function Lattice for Medical Use" Proceedings of NIRS International Seminar on the Application of Heavy Ion Accelerator to Radiation Therapy of Cancer in connection with XXI PTCOG Meeting. 96-99 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Jyunichi Hirota et al.,: "A Ferrite-Loaded, Untuned Cavity with Multiple Power Feeding" Bulletin of the Institute for Chemical Research Kyoto University. 73. 41-49 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Kazuo Hiramoto et al.,: "A Compact Proton Synchrotron with a Combined Function Lattice Dedicated for Medical Use" Bulletin of the Institute for Chemical Research Kyoto University. 73. 11-18 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Akira Noda et al.,: "Design of a Compact Proton Accelerator Facility Dedicated for Cancer Therapy" Proceedings of the 10th Symposium on Accelerator Science and Technology, Hitachinaka, Japan. 413-415 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Junichi Hirota et al.,: "An Untuned Type RF Cavity using Multiple Power Feeding" Proceedings of the 10th Symposium on Accelerator Science and Technology, Hitachinaka, Japan. 79-81 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Kazuyoshi Saito et al.,: "RF Acceleration System of Proton Synchrotron Dedicated for a Compact Synchrotron" Beam Science and Technology, Activity Report, Nuclear Science Research Facility, Institute for Chemical Research, Kyoto Univ.1. 12-16 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Kooji Matsuda et al.,: "A Resonant Beam Extraction Scheme for a Compact Synchrotron" Beam Science and Technology, Activity Report, Nuclear Science Research Facility, Institute for Chemical Research, Kyoto Univ.1. 17-20 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Junichi Hirota et al.,: "A Ferrite Loaded Untuned Type Cavity for a Compact Proton Synchrotron" Proceedings of 1995 Particle Accelerator Conference, Dallas, USA. (in print). 3

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Akira Noda, Yoshihisa Iwashita, Makoto Inoue, Mutuyuki Abe, Junji Konishi and Koji Ono: "Dedicated Accelerator Project for Proton Therapy at Kyoto University" Proceedings of NIRS International Seminar on the Application of Heavy Ion Accelerator to Radiation Therapy of Cancer in connection with XXI PTCOG Meeting. 292-294 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Kazuo Hiramoto, Junichi Hirota, Masatsugu Nishi, Mamoru Katane, Hiroaki Sakurabata, Akira Noda, Yoshihisa Iwashita and Makoto Inoue: "A Compact Proton Synchrotron with a Combined Function Lattice for Medical Use" Proceedings of NIRS International Seminar on the Application of Heavy Ion Accelerator to Radiation Therapy of Cancer in connection with XXI PTCOG Meeting. 96-99 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Kazuo Hiramoto, Junichi Hirota, Tetsurou Norimine, Masatsugu Nishi, Mamoru Katane, Hiroaki Sakurabata, Akira Noda, Yoshihisa Iwashita and Makoto Inoue: "A Compact Proton Synchrotron with a Combined Function Lattice Dedicated for Medical Use" Bulletin of the Institute for Chemical Research, Kyoto University. Vol.73, No.1. 11-18 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Junichi Hirota, Kazuo Hiramoto, Mamoru Katane, Yoshihisa Iwashita Akira Noda and Makoto Inoue: "A Ferrite-Loaded, Untuned Cavity with Multiple Power Feeding" Bulletin of the Institute for Chemical Research, Kyoto University. Vol.73, No.1. 41-49 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Akira Noda, Makoto Inoue, Yoshihisa Iwashita, Toshiyuki Shirai, Masatsugu Nishi, Kazuo Hiramoto and Junichi Hirota: "Desogn of a Compact Proton Accelerator Facility Dedicated for Cancer Therapy" Proceedings of the 10th Symposium on Accelerator Science and Technology, Hitatinaka, Japan. 413-415 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Junichi Hirota, Mamoru Katane, Kazuyoshi Saitou, Masahiro Tadokoro, Fumiaki Noda, Yoshihisa Iwashita, Akira Noda and Makoto Inoue: "An Untuned Type RF Cavity using Multiple Power Feeding" Proceedings of the 10th Symposoum on Accelerator Science and Technology, Hitatinaka, Japan. 79-81 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Kazuyoshi Saito, Junichi Hirota, Mamoru Katane, Masahiro Tadokoro, Fumiaki Noda, Yoshihisa Iwashita, Akira Noda and Makoto Inoue: "RF Acceleration System of Proton Synchrotron Dedicated for Cancer Therapy" Beam Science and Technology, Activity Report of Nuclear Science Research Facility, Institute for Chemical Research, Kyoto University. Vol.1. 12-16 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Kooji Matsuda, Kazuo Hiramoto, Akira Noda and Makoto Inoue: "A Resonant Beam Extraction Scheme for a Compact Synchrotron" Beam Science and Technology, Activity Report of Nuclear Science Research Facility, Institute for Chemical Research, Kyoto University. Vol.1. 21-24 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Junichi Hirota, Kazuo Hiramoto, Masatsugu Nishi, Yoshihisa Iwashita, Akira Noda and Makoto Inoue: "A Ferrite Loaded Untuned Cavity for a Compact Proton Synchrotron" Proceedings of 1995 Particle Accelerator Conference, Dallas, USA. (in print). 3

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Jyunichi Hirota et al.,: "A Ferrite-Loaded, Untuned Cavity with Multiple Power Feeding" Bulletin of the Institute for Chemical Research Kyoto University. 73. 41-49 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Kazuo Hiramoto et al.,: "A Compact Proton Synchrotron with a Combined Function Lattice Dedicated for Medical Use" Bulletin of the Institute for Chemical Research Kyoto University. 73. 11-18 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Akira Noda et al.,: "Design of a Compact Proton Accelerator Facility Dedicated for Cancer Therapy" Proceedings of 10th the Symposium on Accelerator Science and Technology, Hitachinaka, Japan. 413-415 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Junichi Hirota et al.,: "An Untuned Type RF Cavity using Multiple Power Feeding" Proceedings of the 10th Symposium on Accelerator Science and Technology, Hitachinaka, Japan. 79-81 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] Kazuyoshi Saito et al.,: "RF Acceleration System of Proton Synchrotron Dedicated for a Compact Synchrotron" Beam Science and Technology, Activity Report, Nuclear Science Research Facilty, Institute for Chemical Research, Kyoto Univ.1. 12-16 (1996)

    • Related Report
      1995 Annual Research Report
  • [Publications] Kooji Matsuda et al.,: "A Resonant Beam Extraction Scheme for a Compact Synchrotron" Beam Science and Technology, Activity Report, Nuclear Science Research Facility, Institute for Chemical Research, Kyoto Univ.1. 17-20 (1996)

    • Related Report
      1995 Annual Research Report
  • [Publications] Junichi Hirota et al.,: "A Ferrite Loaded Untuned Type Cavity for a Compact Proton Synchrotron" Proceedings of 1995 Particle Accelerator Conference, Dallas, USA. (in print). 3

    • Related Report
      1995 Annual Research Report
  • [Publications] A. Noda,Y.Iwashita,M.Inoue,M.Abe.J.Konishi and K.Ono: "Dedicated Accelerator Project for Proton Therapy at Kyoto University" Proceedings of PTCOG XXI Meeting Chiba,Japan November,1994. (in print).

    • Related Report
      1994 Annual Research Report
  • [Publications] K.Hiramoto et al.,: "A Compact Proton Synchrotron with a Combined Function Lattice for Medical Use" Proceedings of PTCOG XXI Meeting Chiba,Japan November,1994. (in print).

    • Related Report
      1994 Annual Research Report
  • [Publications] J.Hirota,K.Hiramoto,M.Katane.Y.Iwashita,A.Noda and M.Inoue: "A Ferrite-Loaded Untunned Cavity with Multiple Power Feeding" Bulletin of the Institure for Chemical Research,Kyoto University. 73(in print). (1995)

    • Related Report
      1994 Annual Research Report
  • [Publications] K.Hiramoto et al.: "A Compact Proton Synchrotron with a Combined Function Lattice Dedicated for Medical Use" Bulletin of the Institure for Chemical Research,Kyoto University. 73(in print). (1995)

    • Related Report
      1994 Annual Research Report

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Published: 1994-04-01   Modified: 2016-04-21  

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