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Effects of time delays on persistence and global stability of mathematical biological models

Research Project

Project/Area Number 06640303
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field General mathematics (including Probability theory/Statistical mathematics)
Research InstitutionShizuoka University

Principal Investigator

TAKEUCHI Yasuhiro  Shizuoka Univ.Fac.of Eng., Professor, 工学部, 教授 (20126783)

Project Period (FY) 1994 – 1996
Project Status Completed (Fiscal Year 1996)
Budget Amount *help
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1996: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 1995: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 1994: ¥1,300,000 (Direct Cost: ¥1,300,000)
Keywordsmathematical models in biology / persistence / global stability / time delay
Research Abstract

The purpose of this research is to study the effct of time delays introduced in some concrete mathematical models in biology on their persistence and global stability, which are the most fundamental concept in mathematical biology. Further, the research is aimed at the establishment of the method to analyze the general mathematical models in biology with time delays.
The concrete models are :
1. the chemostat models with time delay effect both in the growth process of the species and the recycling process of the materials ;
2. the epidemic models with time delays in the process that the susceptible individuals become infectious ;
3. the medical models with time delays in the phagocytosis of red blood cells by the macrophages.
The results are as follows :
1994 : The global stability of chemostat models is ensured under the sufficiently small time delays (paper 1) ; Also the global stability of epidemic models is guaranteed if they have a constant population size (paper 2).
1995 : The paper 1 is revised and extended for uniform stability (paper 3) ; for epidemic models with varying population size, the set of initial data which ensures for the solution to converge to the endemic state. (paper 7) ; for medical models, the results on control problem of the solution are appeared in (paper 4).
1996 : A nonlinear differential difference inequality is proved and applied for stability analysis of nonlinear retarded or neutral differential difference systems with infinite delays (papers 5,6). The method can be applied not only for mathematical models in biology but also for general models.

Report

(4 results)
  • 1996 Annual Research Report   Final Research Report Summary
  • 1995 Annual Research Report
  • 1994 Annual Research Report
  • Research Products

    (31 results)

All Other

All Publications (31 results)

  • [Publications] E.Beretta: "Global stability for chemostat aquations with delayed nutriest recycling" Nonlinear World. 1. 291-306 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] E. Beretta: "Global stability of an SIR epidemic model with time delays" J. Math. Biology. 33. 250-260 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] E.Beretta: "Qualitative properties of chemostat equations with time delays" J. of Biological Systems. 3. 689-696 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] W. B. Ma: "Instability aualysis of nonlineer neutral differential differnce systems with infinite delays" Dynamics of Continuous,Discrate and Impulsive Systems. 2. 437-460 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] W. B. Ma: "As nonlinear differential difference inequality and instability analysis of nonlinear retasded differential difference large scale systems with infinite dalays" Nonlinear World. (印刷中).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] E.Beretta: "Convergence results in SIR epidemic modds with varying popultion size" Nonlinear Analysis,TMA.(印刷中).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Y.Takeuchi: "Global Dynamical Properties of Lotka-Volterra Systems" World Scientific Publishing Co. Pte. Ltd., 302 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 竹内康博: "種の共存と生息地の構造" 共立出版(株), 14 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] E.Beretta and Y.Takeuchi: "Global stability for chemostat equations with delayd nutrient recycling." Nonlinear World. Vol. 1. 291-306 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] E.Beretta and Y.Takeuchi: "Global stability of an SIR epidemic model with time delays." J.Math.Biology. Vol.33. 250-260 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] E.Beretta and Y.Takeuchi: "Qualitative proparties of chemostat equations with time delays." J.of Biological Systems. Vol.3. 689-696 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] E.Beretta, F.Solimono and Y.Takeuchi: "A mathematical model for drug administration by using the phagocytosis of red blood cells" J.Math.Biology. Vol.35. 1-19 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] W.B.Ma and Y.Takeuchi: "Instability analysis of nonlinear rsutral differential difference systems with infinite delays" Dynamics of Continuous, Discrete and Inpulsive Systems. Vol.2. 437-460 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] W.B.Ma and Y.Takeuchi: "A nonlinear differential difference inequality and instability analysis of nonlinear retarded differential large scale systems with infinite delays." Nonlinear World. (in press).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] E.Beretta and Y.Takeuchi: "Convergence results in SIR epidemic models with vorying population size." Nonlinear Analysis TMA. (in press).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Y.Takeuchi: Global Dynamical Properties of Lotka-volterra Systems. World Scientific Pub., 302 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Y.Takeuchi: Species Coexistence and Structures of Habitat. Kyoritsu Pub., 14 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] E.Beretta: "Global stability for chemostat equations with delayed nutriest recycling" Nonlinear World. 1. 291-306 (1994)

    • Related Report
      1996 Annual Research Report
  • [Publications] E.Beretta: "Global stability of an SIR epidemic model with time delays" J.Math.Biology. 33. 250-260 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] E.Beretta: "Qualitative properties of chemostat equations with time delays" J.of Biological Systems. 3. 689-696 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] W.B.Ma: "Instability anal ysis of nonlinear neutral differential difference systems with intinite delays" Dynamics of Continuous,Discrete and Impulsive Systems. 2. 437-460 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] W.B.Ma: "A nonlinear differential difference inequality and instability analysis of nonlinear retarded differential difference large scale systems with in finite dalays" Nonlinear World. (印刷中).

    • Related Report
      1996 Annual Research Report
  • [Publications] E.Beretta: "Convergence results in SIR epidemic models with varying popalation size" Nonlinear Analysis TMA. (印刷中).

    • Related Report
      1996 Annual Research Report
  • [Publications] Y.Takeuchi: "Global Dynamical Properties of Lotka-Voltena Systems" World Scientific Pub.Co.Ptd.Ltd, 302 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 竹内康博: "種の共存と生息地の構造" 共立出版(株), 14 (1997)

    • Related Report
      1996 Annual Research Report
  • [Publications] E.Beretta: "Global stability for chemostat equations with delayed nutrient recycling" Nonlinear World. 1. 291-306 (1994)

    • Related Report
      1995 Annual Research Report
  • [Publications] E.Beretta: "Global stability of an SIR epidemic model with time delays" J. Math. Biology. 33. 250-260 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] E.Beretta: "Qualitative properties of chemostat equations with time delays" J. of Biological Systems. 3. (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] E.Beretta: "Convergence results in SIR epidemic models with varying population siz" Nonlinear Analysis, TMA.

    • Related Report
      1995 Annual Research Report
  • [Publications] E.Beretta: "Global stability for chemostat equations with delayed nutrient recyclig" Nonlinear World. 1. 291-306 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] E.Beretta: "Global stability of an SIR epidemic model with time delays" J.Math.Biology. 33. 250-260 (1995)

    • Related Report
      1994 Annual Research Report

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Published: 1994-04-01   Modified: 2016-04-21  

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