| Budget Amount *help |
¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1995: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1994: ¥1,000,000 (Direct Cost: ¥1,000,000)
|
|---|
| Research Abstract |
This study was carried out to establish fundamental techniques of measuring blood flow of the abdominal and pelvic organ vessels in dogs and cows, using Doppler ultrasonography, and to clarify the clinical usefulness of this method.
1) Using transcutaneous and transesophageal approaches, consistent and clinically useful anatomic and Doppler imaging planes for measuring the portal and hepatic veins of the liver and the renal arteries were gained in normal dogs. Additionally, to estimate the accuracy of the quantitative measurement of blood flow using Doppler ultrasonography, we did simultaneous measurement of canine renal arterial blood flow by pulsed Doppler method and electromagnetic flowmeter, and found a significant correlation between two methods. Clinical application of this method to various diseases of the kidney and liver showed its great potential to diagnose and to evaluate the hemodyanamic status.
2) In healthy cattle, transrectal ultrasonography was used to gain B-mode and Doppler imaging views suited for blood flow measurement of the abdominal and pelvic organ vessels such as the left renal, mesenteric, internal and external iliac, femoral, uterine, and ovarian arteries.
3) We conducted a study of the effect of new-typed transpulmonary ultrasound contrast agents (Alubunex, TA508) on Doppler signal enhancement of flow in healthy dogs and dogs with liver, spleen, and other organ tumors. The results suggested a potential, clinical usefulness of this new contrast agents.
|
