| Project/Area Number |
06670090
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
Environmental physiology (including Physical medicine and Nutritional physiology)
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| Research Institution | KOBE WOMEN'S UNIVERSITY |
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Principal Investigator |
HIRATA Kouzou KOBE WOMEN'S UNIV., DEPT.ENVIRON.PHYSIOL., PROFESSOR, 家政学部, 教授 (70110624)
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| Co-Investigator(Kenkyū-buntansha) |
SUYAMA Tomoko KOBE WOMEN'S JUNIOR COLLEGE,ASSISTANT, 食物栄養科, 助手
吉田 美奈子 神戸女子大学, 助手
東渕 とも子 神戸女子短大, 助手
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| Project Period (FY) |
1994 – 1995
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| Project Status |
Completed (Fiscal Year 1995)
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| Budget Amount *help |
¥1,900,000 (Direct Cost: ¥1,900,000)
Fiscal Year 1995: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1994: ¥1,400,000 (Direct Cost: ¥1,400,000)
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| Keywords | SKIN BLOOD FLOW / CAPILLARY VESSEL / ARTERIOVENOUS ANASTOMOSES / LOCAL WARMING / TEMPERATURE REGULATION / THERMAL FACTOR / NON-THERMAL FACTOR / VIDEOMICROSCOPE / 動静脈吻合(AVA) / 体温 / 温熱刺激 / 非温熱性刺激 / レーザードップラー血流計 |
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| Research Abstract |
It is well known that thermal stimuli to the skin reflexively induce skin vasoconstriction or vasodilation through thermoregulatory center in the hypothalamus, and that the regulation of finger blood flow including arteriovenous anastomoses (AVA) is different from that of capillary blood flow in the ordinary skin.
To investigate the effects of local warming on the regulation of skin blood flow, six healthy subjects were measured finger capillary blood flow (FBF_<cap>) with laser-Doppler flowmeter at an ambient temperature of 23.7 to 25.5ﾟC.Subjects were cooled or warmed forearm by the special water-perfused tube at a water temperature (T_<forearm>) between 1ﾟC and 38ﾟC and feet by the water immersion (T_<feet>) at a temperature of 37ﾟC-40ﾟC.When T_<forearm> decreased from 40ﾟC to 1ﾟC at the T_<feet> of 40ﾟC,FBF_<cap> did not change at all. When T_<forearm> decreased from 37ﾟC to 3ﾟC at the T_<feet> of 37ﾟC,FBF_<cap> diminished 180mv to 100mv. And when T_<forearm> rose from 3ﾟC to 37ﾟC at the T_<feet> of 37ﾟC again, FBF_<cap> was totally recovered. Then, when T_<feet> increased from 37ﾟC to 38ﾟC at T_<forearm> of 37ﾟC,FBF_<cap> fell without any cool stimuli.
These results suggest that decreased finger capillary blood flow was contributed to counterbalance AVA vasodilation reflexively induced by local feet warming and was called "steal effect" on capillary blood flow.
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