| Project/Area Number |
06670508
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
内科学一般
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| Research Institution | Meiji College of Oriental Medicine |
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Principal Investigator |
YANO Tadashi Meiji College of Oriental Medicine, 鍼灸学部, 教授 (70166560)
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| Co-Investigator(Kenkyū-buntansha) |
FUKUDA Fumihiko Meiji College of Oriental Medicine, 鍼灸学部, 助手 (80238485)
ISHIZAKI Naoto Meiji College of Oriental Medicine, 鍼灸学部, 助手 (90212878)
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| Project Period (FY) |
1994 – 1995
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| Project Status |
Completed (Fiscal Year 1995)
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| Budget Amount *help |
¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1995: ¥300,000 (Direct Cost: ¥300,000)
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| Keywords | nerve blood flow / electroacupuncture / sciatic nerve / laser doppler / flowmetry / 鍼 / 自律神経 / 鍼通電 |
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| Research Abstract |
As a preparatory study on the effect of acupuncture treatment of diabetic neuropathy, we investigated the effect of electroacupuncture on the sciatic blood flow in rats. Nerve blood flow was measured with laser doppler flowmetry. The rats were divided into following three groups ;
1) rats stimulated with low frequent (1Hz, 5Hz) electroacupuncture.
2) rats stimulatedwith highfrequent (20Hz, 100Hz) electroacupuncture.
3) rats stimulated in their tails with pinch.
In electroacupuncture group, rats were stimulated in their plantae.
In the rats stimulated with low frequent electroacupuncture little change was seen, while temporal increase of both blood flow and blood pressure were observed in the rats stimulated with high frequent electroacupuncture and in the rats applied pinch stimulation. Also these reactions were all inhibited by administration of phentolamine (alpha receptor blocker).
Those results suggests the increase of sciatic blood flow induced by high frequent electroacupuncture and pinch stimulation are dependent on the blood pressure.
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