| Project/Area Number |
06670923
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
Radiation science
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| Research Institution | Shimane Medical University |
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Principal Investigator |
SUGIMURA Kazuro Shimane Med.Univ.Dept.Radiology, Professor, 医学部, 教授 (00136384)
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| Co-Investigator(Kenkyū-buntansha) |
KAJI Yasushi Shimane Med.Univ.Dept.Radiology, Assistant, 医学部, 助手 (10273947)
ISHIDA Jun Shimane Med.Univ.Dept.Radiology, Assistant, 医学部, 助手 (00212887)
YOSHIKAWA Kazuaki Shimane Med.Univ.Dept.Radiology, Assistant, 医学部, 助手 (70200954)
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| Project Period (FY) |
1994 – 1995
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| Project Status |
Completed (Fiscal Year 1995)
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| Budget Amount *help |
¥1,900,000 (Direct Cost: ¥1,900,000)
Fiscal Year 1995: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1994: ¥1,200,000 (Direct Cost: ¥1,200,000)
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| Keywords | 1H-MR specroscopy / chemical shift imaging / prostatic cancer / 体腔内コイル |
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| Research Abstract |
The purpose of our study was to evaluate the usefulness of 1H-MR specroscopy (MRS), especially chemical shift imaging (CIS), in the patients with prostatic cancer.
We used 1.5 T super conductive MR unit in this study. Initially, 2D-CIS was performed in healthy volunteer, using body coil as transmission coil and endorectal surface coil as receiver coil. We could detect the citrate peak, which is known as the rich substance in normal prostate gland and less in prostate cancer. But the signal from citrate was so weak, that we could not show amount of citrate in each voxel. The reason why we could not success was poor signal to noise ratio due to incomplete fat- and water-suppression and lower sensitivity of endorectal receiver coil.
Now we try to improve the receiver coil and fat- and water-suppression method. Then we will go next step, that is to say, clinical evaluation in the patient with prostatic cancer.
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