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Dynamic MRI of Soft-tissue Tumors-Comparison of MR Imaging and Histologic Findings

Research Project

Project/Area Number 06670944
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionKurume University

Principal Investigator

EDAMITSU Osamu  Kurume University School of Medicine, Fellow, 医学部, 助手 (30176771)

Co-Investigator(Kenkyū-buntansha) HIRAOKA Kouji  Kurume University School of Medicine, Fellow, 医学部, 助手 (10268914)
UCHIDA Masafumi  Kurume University School of Medicine, Assistant Professor, 医学部, 講師 (50168704)
NISHIMURA Hiroshi  Kurume University School of Medicine, Associate Professor, 医学部, 助教授 (20164593)
Project Period (FY) 1994 – 1996
Project Status Completed (Fiscal Year 1996)
Budget Amount *help
¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1996: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1995: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1994: ¥400,000 (Direct Cost: ¥400,000)
KeywordsSoft-tissue tumors / MRI / dynamic MRI
Research Abstract

The MR and dynamic MR images of 160 patients with soft-tissue masses were examined. In 122 patients, the diagnosis was proved by analysis of specimens. We correlated in detail MR findings with histopathologic findings in 18 tumors. We evaluated prospectively the differential diagnosis in recent 55 patients.
We could speculate a lot of components (ex. : fat, fatty necrosis, cyst, cystic necrosis, myxomatous component, cartilage, collagen, hemorrhage, hemorrhagic necrosis, coagulated necrosis and bean-cured refuse like component) and the vascularity of soft-tissue mass by the MR and dynamic MR images in almost all patients. The composition and distribution of the components and the clinical findings could make the appropriate differential diagnosis easy. Especially, the specific diagnosis of lipmatous tumors, hemangiomatous neoplasms, peripheral nerve tumors, and myxoid tumors could become posible in a lot of cases. In 115 patients, the dynamic MRI pattern was help in distinguishing benign from malignant soft-tissue tumors. But it was imposible to distinguish perfectly benign from low grade malignant tumors, and active inflammatory from malignant masses. The change of size, internal structure, and the slope of the dynamic MRI pattern was helpful to assess the appropriate responses to chemotherapy and irradiation.
Dynamic 3D Gd-enhanced MR angiography was a new effective technique providing appropppriate essential vascular anatomic information and tumor vascularity prior to surgery, and for assessing the responses to chemotherapy and irradiation.

Report

(4 results)
  • 1996 Annual Research Report   Final Research Report Summary
  • 1995 Annual Research Report
  • 1994 Annual Research Report
  • Research Products

    (12 results)

All Other

All Publications (12 results)

  • [Publications] 枝光理: "Dynamic MRI を用いた軟部腫瘍の診断-MR像と病理との対比による研究-" INNERVISION. 11. 51-51 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 西村浩: "部位別にみるMRI画像診断;骨・軟部組織" Progress in Medicine. 15. 2309-2318 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 西村浩: "骨・軟部疾患のMRI診断" 映像情報. 27. 65-71 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 西村浩: "骨・軟部疾患-主に腫瘤病変" 臨床画像. 12. 188-209 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Osamu Edamitsu: "Dynamic MRI of Soft-tissue Tumors-Comparison of MR Imaging and Histologic Findings" INNERVISION. 11. 51-51 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Hiroshi Nishimura: "Bone and Soft-tissue : MR Imaging" Progress in Medicine. 15. 2309-2318 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Hiroshi Nishimura: "MR Imaging of Bone and Soft-tissue Masses" Eizo Joho Medical. 27. 65-71 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Hiroshi Nishimura: "Bone and Soft-tissue Masses" Clinical Imagiology. 12. 188-209 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 枝光 理: "Dynamic MRIを用いた軟部腫瘍の診断-MR像と病理との対比による研究" INNERVISION. 11・8. 51-51 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 西村 浩: "部位別にみるMRI画像診断;骨・軟部組織" Progress in Medicine. 15・11. 2309-2318 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] 西村 浩: "骨・軟部疾患のMRI診断" 映像情報. 27・25. 65-71 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 西村 浩: "骨・軟部疾患-主に腫瘍性病変" 臨床画像. 12・10. 188-209 (1996)

    • Related Report
      1996 Annual Research Report

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Published: 1994-04-01   Modified: 2016-04-21  

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