| Project/Area Number |
06671765
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
Ophthalmology
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| Research Institution | Okayama University |
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Principal Investigator |
OHTSUKI Hiroshi Okayama Univ.Medical School, Associate Professor, 医学部, 助教授 (70093672)
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| Co-Investigator(Kenkyū-buntansha) |
HASEBE Satoshi Okayama Univ.Medical School, Assistant Doctor, 医学部・附属病院, 助手 (20263577)
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| Project Period (FY) |
1994 – 1995
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| Project Status |
Completed (Fiscal Year 1995)
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| Budget Amount *help |
¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 1995: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 1994: ¥1,400,000 (Direct Cost: ¥1,400,000)
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| Keywords | Microvascular change / Casting / Tenotomy / Rabbit / Anterior eye segment ischemia / 血管樹脂鋳型標本 / 外眼筋切腱 / 長後毛様動脈閉塞 / 角膜新生血管 / ウサギ |
|---|
| Research Abstract |
Using scanning electron microscopy of methylmethacrylate ocular microvascular luminal castings, the anterior eye segnent vasculature after tenotomy was documented and compared to that after occlusion of the bilateral long posterior ciliary arteries and that in the eyes that were not subjected to any surgical intervention. Five days and 1 week after the surgical intervention with tenotomy, microvascular change secondary to the anterior segment ischemia was not apparent, but 2 weeks after the tenotomy subtle evidence of ischemia such as new vessels in the iris was observed. Seven week after tenotomy, marked microvascular change was observed where corneal new vessels arose from the superior perilimbal arteries. In contrast we found prominent microvascular change 2 weeks after the occlusion of the long posterior ciliary arteries. From these findings, tenotomy of the rabbit eye causes microvascular change similar to that in occlusion of the long posterior ciliary arteries. This result suggests that the anterior ciliary artery of the rabbit contributes the blood flow to the anterior eye segment and also has a stronger connection with the long posterior ciliary artery than previously reported.
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