• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Morphological analysis of the taste-reception mechanism in the gustatory cell

Research Project

Project/Area Number 06671838
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Morphological basic dentistry
Research InstitutionThe Nippon Dental University

Principal Investigator

SUMIO Yoshie  The Nippon Dental University, School of Dentistry at Niigata, Associate Professor, 新潟歯学部, 助教授 (30095278)

Project Period (FY) 1994 – 1995
Project Status Completed (Fiscal Year 1995)
Budget Amount *help
¥1,700,000 (Direct Cost: ¥1,700,000)
Fiscal Year 1995: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1994: ¥900,000 (Direct Cost: ¥900,000)
KeywordsGustatory Stimulation / Taste Bud / Gustatory Cell / Dense-cored Vesicle / Exocytosis / Gustatory Nerve / Synapse / Guinea Pig / 味覚刺激 / 味覚受容細胞
Research Abstract

This study was conducted to solve the following problems by using the taste bud of circumvallate papillae in guinea pigs.
1. Do defferent qualities of basic taste stimuli cause variable responses of the gustatory cells?
Although not all the gustatory cells responded to each stimulus, responsive cells displayd common changes for all the stimuli : dense-cored vesicles accumulated in the synaptic area of the gustatory cells were exocytosed toward the nerves. Probably as a result of their rapid release, the vesicles were decreased in number at the synapses.
2. What is the response rate of the gustatory cell stimulated with each basic taste substance?
Appearance rates of the gustatory cells responding to each basic taste stimulant are as follows : 37.5% (15/40 cells) for bitter taste, 27.0% (10/37 cells) for umami taste, 26.8% (11/41 cells) for sour taste, 25.7% (9/35 cells) for salty taste, and 12.9% (4/31 cells) for sweet taste. These data indicate that the circumvallate taste buds in guinea pigs are the most sensitive for bitter taste and the least for sweet tasle.
3. Are the individual gustatory cells supplied with more than two independent nerve fibers?
Three-dimensionally reconstructed taste buds showed that eight gustatory cells out of ten cells examined, made synaptic contacts with separate nerves up to ten fibers. The other two gustatory cells were supplied with single nerve fibers. Most synapses were localized to the baso-lateral surface of the gustatory cells.

Report

(3 results)
  • 1995 Annual Research Report   Final Research Report Summary
  • 1994 Annual Research Report
  • Research Products

    (3 results)

All Other

All Publications (3 results)

  • [Publications] Sumio Yoshie: "Histological localization of the sweet taste receptor in rat taste buds by the use of gurmarin,a sweet taste-suppressing peptide" Archives of Histology and Cytology. 57. 531-534 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] S.Yoshie, A.Miyasaka and T.Imoto: "Histological localization of the sweet taste receptor in rat taste buds by the use of gurmarin, a sweet taste-suppressing pcptide." Arch.Histol.Cytol.Vol.57, No.5. 531-534 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Sumio Yoshie: "Histological localization of the sweet taste receptor in rat taste buds by the use of gurmarin, a sweet taste-suppressing peptide" Archives of Histology and Cytology. 57. 531-534 (1994)

    • Related Report
      1995 Annual Research Report

URL: 

Published: 1994-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi