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Effects of inner ear pathology on the input impedance of the cochlea

Research Project

Project/Area Number 06807134
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Otorhinolaryngology
Research InstitutionEhime University

Principal Investigator

GYO Kiyofumi  Ehime University, School of Medicine Otolaryngology, Associate Professor, 医学部, 助教授 (00108383)

Co-Investigator(Kenkyū-buntansha) HYOUDOU Masamitsu  Ehime University, School of Medicine Otolaryngology, Assistant Professor, 医学部・付属病院, 助手 (00181123)
SATO Hidemitsu  Ehime University, School of Medicine Otolaryngology, Assistant Professor, 医学部, 助手 (30187223)
Project Period (FY) 1994 – 1995
Project Status Completed (Fiscal Year 1995)
Budget Amount *help
¥1,900,000 (Direct Cost: ¥1,900,000)
Fiscal Year 1995: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1994: ¥1,300,000 (Direct Cost: ¥1,300,000)
Keywordsacoustic impedance / stapes mobility / piezoelectric ceramic / inner ear pressure / perilymphatic fistula / laser-doppler intorferometor / 外リンパ痿 / アブミ骨固着 / 蝸牛窓閉鎖
Research Abstract

The effects of inner ear pathology on the input impedance of the cochlea were studied in animals using a laser-doppler interferometer or a piezoelectric ceramic device of our design. In guinea pigs, vibration amplitudes of the umbo were measured before and after either one of the following three procedures ; rupture of the round window membrane, destruction of the cochlea and increase in inner ear pressure. Rupture of the round window membrane caused increase in umbo vibration up to 10 dB in mid-frequencies. Destruction of the cochlea resulted in 10 dB increase in the vibration at all the frequencies. Pressure loading to the inner ear induced the decrease in the vibration at low frequencies and the increase at mid-frequencies. This suggested that the changes in the inner ear impedance can be detected by the vibration mode of the tympanic membrane.
Chaine cochlear input impedance were measured uaing a piezoelectric device. It was designed for future use in human subjects during middle ear surgery. The impedance value was 3.9 Megohm at 1 kHz, which gradually increased at higher frequencies.

Report

(3 results)
  • 1995 Annual Research Report   Final Research Report Summary
  • 1994 Annual Research Report
  • Research Products

    (16 results)

All Other

All Publications (16 results)

  • [Publications] 暁 清文: "犬内耳インピーダンス測定の試み" Audiology Japan. 37. 463-464 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 暁 清文: "内耳インピーダンス術中測定の試み" Audiology Japan. 38. 639-640 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 篠原 孝之: "レーザードップラー法による鼓膜およびアブミ骨振動の測定" Audiology Japan. 38. 629-630 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 西原 信成: "レーザードップラー速度計によるヒト鼓膜振動の測定" Audiology Japan. 38. 631-632 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 佐藤 英光: "圧電素子を用いた内耳インピーダンスの測定-イヌによる実験的研究" 耳鼻臨床. 88. 1353-1359 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Kiyofumi Gyo, Hidemitsu Sato, Hiroshi Aritomo: "Measurement of canine inner ear impedance." Audiology Japan. 37. 463-464 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Kiyofumi Gyo, Hidemitsu Sato: "Measurement of inner ear impedance during middle ear surgery." Audiology Japan. 38. 639-640 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Takayuki Shinohara, Shinsei Nishihara, Kiyofumi Gyo: "Measurement of fympanic membrane and stapes vibration using a laser-doppler interferometer." Audiology Japan. 38. 629-630 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Shinsei Nishihara, Takayuki Shinohara, Kiyofumi Gyo: "Human tympanic menbrane vibration measured by use of a laser-doppler interferometer" Audiology Japan. 38. 631-632 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] Hidemitsu Sato: "Measurement of inner ear impedance using a piezoelectric element-An experimental study in dog" Proctica Otologica (Kyoto). 88. 1353-1359 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 暁清文: "犬内耳インピーダンス測定の試み" Audiology Japan. 37. 463-464 (1994)

    • Related Report
      1995 Annual Research Report
  • [Publications] 暁清文: "内耳インピーダンス術中測定の試み" Audiology Japan. 38. 639-640 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 篠原孝之: "レーザードップラー法による鼓膜およびアブミ骨振動の測定" Audiology Japan. 38. 629-630 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 西原信成: "レーザードップラー速度計によるヒト鼓膜振動の測定" Audiology Japan. 38. 631-632 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 佐藤英光: "圧電素子を用いた内耳インピーダンスの測定-イヌによる実験的研究-" 耳鼻臨床. 88. 1353-1359 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 暁 清文,他: "犬内耳インピーダンス測定の試み" Audiology Jpn. 37. 463-464 (1994)

    • Related Report
      1994 Annual Research Report

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Published: 1994-04-01   Modified: 2016-04-21  

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