| Project/Area Number |
07042011
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| Research Category |
Grant-in-Aid for international Scientific Research
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| Allocation Type | Single-year Grants |
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| Section | Special Cancer Research |
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| Research Institution | Kobe Pharmaceutical University |
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Principal Investigator |
KATO Atsushi Professor, Kobe Pharmaceutical University, 薬学部, 教授 (50068326)
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| Co-Investigator(Kenkyū-buntansha) |
アルバード R. チンバザサ動植物園兼アンタナリボ大学, 薬学部, 園長,助教授
MATHENGE S.G. Assistant, University of Nairobi Department of Batany, 理学部, 助手
JUMA F.D. Professor, University of Nairobi Department of Medicine, 医学部, 教授
TACHIBANA Yoko Assistant, Kobe Pharmaceutical University, 薬学部, 助手 (20207054)
TOKUDA Harukuni Assistant, Kyoto Prefectural University of Medicine, 医学部, 助手 (60111960)
ALBERT R. Director, Botanical and Zoological Park, Tsimbazaza and Associate Professor, Ant
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| Project Period (FY) |
1995
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| Project Status |
Completed (Fiscal Year 1995)
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| Budget Amount *help |
¥4,100,000 (Direct Cost: ¥4,100,000)
Fiscal Year 1995: ¥4,100,000 (Direct Cost: ¥4,100,000)
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| Keywords | Anticancer / Chemoprevention / Antipromotor / African medicines / Uvaria sp. / Maytenus sp. / Natural medicines / Mitogenic activity / Hypoxis sp. |
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| Research Abstract |
Many naturally occurring anticancer substances have been isolated from plants and marine products, and their chemical modification are tried for further strong effect and safety as medicine in various institutes. A number of these compounds are used clinical medicines.
Recently, anticancer substances searched in natural resources are taken seriously not only as a killer of cancer cell but also as preventive activator against carcinogenesis.The substances having potent chemical preventive action against cancer are found in everyday our foods.We intend to search more strong anticancer substances without side effects and inclusive of a chemoprevention in Africa traditional medicines and unused natural resources.
In this exploration, we have collected the plants of 15 species (Uvaria sp., Maytenus sp., ... etc.) in Kenya and Madagascar, which will be subjected to screening test for inhibition to various carcinogenesis.
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