| Project/Area Number |
07305036
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 総合 |
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| Research Field |
生物・生体工学
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| Research Institution | The University of Tokyo |
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Principal Investigator |
FURUSAKI Shintaro The University of Tokyo Graduate School of Engineering Professor, 大学院・工学系研究科, 教授 (40011209)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAO Shin-ichi The University of Tokyo Graduate School of Engineering Professor, 大学院・工学系研究科, 教授 (00155665)
OHYA Haruhiko Yokohama National University Dept. of Material Science and Chem. Eng. Professor, 工学部, 教授 (40017950)
INUI Kenichi Kyoto University Faculty of Pharmaceutical Science Professor, 医学部, 教授 (70034030)
TAKAKUWA Yuichi Tokyo Women's Medical College Dept. of Biochemistry Professor, 教授 (40113740)
OHKI Kazuo Tohoku University Faculty of Science Professor, 理学部, 教授 (80115394)
宮嶋 孝一郎 京都大学, 薬学部, 教授 (30025689)
野澤 義則 岐阜大学, 医学部, 教授 (10021362)
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| Project Period (FY) |
1995 – 1996
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| Project Status |
Completed (Fiscal Year 1996)
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| Budget Amount *help |
¥12,200,000 (Direct Cost: ¥12,200,000)
Fiscal Year 1996: ¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 1995: ¥8,700,000 (Direct Cost: ¥8,700,000)
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| Keywords | biological membrane / synthetic membrane / recognition of materials / signal transmission / selective transport |
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| Research Abstract |
Cyclodextrin having molecular recognition function based on bioaffinity were introduced into reverse micelles, and selective extraction of glucoamylase from alpha-amylase was succeeded.
Molecular imprint method has been applied to introduce amino-acid like structure into synthetic membrane and the membrane having recognition ability for optical isomers could be developed. Inorganic ion exchange membranes which recognized Li ion were prepared and the membranes selectively transpoeted Li ion.
Using cDNA cloning technique, structure and selective transport property of peptide and organic ion transporters were made clear. Thermosensitive gating function could be introduced into polymeric membrane and on-off operation of water permeation and selective transport and concentration of surfactant were succeeded.
Functional molecules which can transform external information and energy to internal change of electron state and structure were introduced into conductive polymer matrix, and information and energy conversion membranes could be synthesized.
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