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Development of neurobehavioral methods in occupational and environmental health and application of them to neurological, psychological and behavioral disorders.

Research Project

Project/Area Number 07307029
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section総合
Research Field Public health/Health science
Research InstitutionUniversity of Tokyo

Principal Investigator

ARAKI Shunichi  University of Tokyo, School of Medicine, Professor, 大学院・医学系研究科, 教授 (00111493)

Co-Investigator(Kenkyū-buntansha) KAWAKAMI Norito  Gifu University, School of Medicine, Associate Professor, 医学部, 助教授 (90177650)
KOBAYASHI Fumio  Aichi Medical University, School of Medicine, Professor, 医学部, 教授 (80135342)
KISHI Reiko  Hokkaido University, School of Medicine, Professor, 医学部, 教授 (80112449)
IGISU Hideki  University of Occupatioal and Environmental Health, Institute of Industrial Ecol, 産業生態科学研究所, 教授 (60108686)
TAKEUCHI Yasuhiro  Nagoya University School of Medicine, Professor, 医学部, 教授 (90022805)
横山 和仁  東京大学, 医学部, 助教授 (00158370)
Project Period (FY) 1995 – 1996
Project Status Completed (Fiscal Year 1996)
Budget Amount *help
¥8,600,000 (Direct Cost: ¥8,600,000)
Fiscal Year 1996: ¥8,600,000 (Direct Cost: ¥8,600,000)
KeywordsOccupational and environmental health / neurobehavioral disorders / neurophysiological methods / neurochemical markers / neurobehavioral test battery / Imaging / Psychosocial factors / Molecular biology / 分子生物学的方法
Research Abstract

The study was conducted through collaboration of members of the Japanese Society for Industrial Health and Japanese Society of Behavioral Medicine, who belonged to several independent institutions, aiming at establishing neurobehavioral methods and at promotingresearches on neurological, psychological and behavioral disorders in occupational and environmental health. Focus of the study was as follows :
1.To establish sensitive and reliable methods which are feasible for studies in preventive medicine, in relation to new topics on the methodology of neurobehavioral research in occupational and environmental health, viz.neurophysiology, neurobehavioral test battery, imaging techniques, neurochemical markers, molecular biology, psycho-social factors, and behavioral medicine.
2.To identify subclinical neurological, psychological and behavioral effects of wide variety of occupational and environmental factors and establish their dose-effects relationships, using the above new methods.
3.To clarify risk factors of major occupational and environmental disorders such as neurotoxic diseases, work-related diseases including stress disorders and "life-style disease" and preventive strategies for them.
As a result, original and review papers, oral and poster presentations at international and national meetings, and monographs were made as listed in the research report attached, of which 31 papers are reproduced in the book.

Report

(3 results)
  • 1996 Annual Research Report   Final Research Report Summary
  • 1995 Annual Research Report
  • Research Products

    (130 results)

All Other

All Publications (130 results)

  • [Publications] Murata,K.: "Subclinical impairment in the median nerve across the carpal tunnel among female VDT operators" International Archives of Occupational and Environmental Health. 68. 75-79 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Fujmura,Y.: "Changes in the distribution of nerve conduction velocities in diabetics" Tohoku Journal of Experimental Medicine. 178. 177-185 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Tanigawa,T.: "Decreases in subpopulations of lymphocytes and natural killer cells in the blood of retired chromate worker" International Journal of Occupational and Environmental Health. 2. 222-225 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Tanigawa,T.: "Increase in CD57+CD16-lymphocytes in workers exposed to benzidine and beta-naphtylamine" International Archives of Occupational and Environmental Health. 69. 69-72 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Tamiya,N.: "Gender difference in the utilization and user's characteristics of community rehabilitation programs for cerebrovasculardisease patients in Japan" International Journal for Quality in Health Care. 8. 359-366 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Yokoyama,K.: "Subsclinical vestibulo-cerebellar,anterior cerebellar lobe and spinocerebellar effects in lead workers in relation to concurrent and past exposure" Neurotoxicology. 18. 371-380 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Kawakami,N.: "Effects of job strain on helper-inducer (CD4+CD29+) and suppress-inducer (CD4+CD45RA+) T cells in Japanese blue-collar workers" Psychother Psychosom. 66. 192-198 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Nakata,A.: "Effects of uncontrollable and controllable electric shocks" Nouroimmunomodulation. 3. 336-341 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Araki,S: "Neurophysiological methods in occupational and environmental health" Environmental Research. 73. 42-51 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Araki,S.: "Biobehavioral approach in occupational,environmental and community Health" Journal of Epidemiology. 6(suppl). S79-88 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Kamijma, Takeuchi Y et al: "Toxic effects of hexane derivatives on cultured rat schurarn cells." Toxicol. 108巻. 25-31 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Aiba I, Takeuchi et al: "Changes in magnetic resonance imaging and clinical signs in a case of chronic toluene intoxicetion by sniffing" J Occur Health. 38巻. 13-19 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Kawakami N,et al.: "A controlled study on effects of a work environment-oriented stress reduction on depressive symptoms in Japanese blue-collar works." Scandinavian Journal of Work Environment and Health. 23. 54-59 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Kawakami N,et al.: "Occupational factors,smoking habits and tobacco withdrawal symptoms among male Japanese employees." Industrial Health. 35. 9-15 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Kawakami N,et al.: "Prevalence of mood and anxiety disorders in a working population in Japan." Journal of Occupational and Environmental Medicine. 38. 899-905 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Aoki R,et al.: "Life style determinants for social activity levels among the Japanese elderly" Archives of Gerontology and Geriatrics. 22. 261-269 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Kawakami N,et al.: "Reliability and validity of the Japanese version of Job Content Questionnaire replication and extension in computer company employees." Industrial Health. 34. 295-306 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Kishi,R.: "Effect of prenatal exposur to styrene on the neurobehavioral development,activit,metor co-ordination and learning behavior" Neurotoxicology and teratology. 17-2. 121-130 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Shibata E, Takeuchi Y et al: "Digital nerve conduction nelo citics et workers exposed to hevane and toluene." Arch Complex Environ Studies. 7巻. 47-49 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Kondo H, Takeuchi Y et al: "Toluene induces behavioral activation without effecting striatal dopamine metabalism in the rat : selaciocal and miorodiabysis studies." Pharmacol Biochem Behav. 51巻. 97-101 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Matsuoka M, Matsumura H, Igisu H: "Creatine kinase activities in brain and blood : possible neurotoxic indicator of acrylamide intoxication" Occupational and Environmental Medicine. 53・7. 468-471 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Matsuoka M, Igisu H: "Induction of c-fos expression by tributyltin in PC12 cells : involvement of intracellular Ca^<2+>" Environmental Toxicology and Pharmacology. 2. 273-380 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Matsumura H, Matsuoka M, Igisu H, Ikeda M: "Cooperative inhibition of acetylcholinesterase activities by hexachlorophene in human erythrocytes" Archives of Toxicology. 71. 151-156 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Xu Z, Iryo Y, Matsuoka M, Igisu H,Ikeda M: "Suppression of pentylenetetrazol-induced seizures by carnitine in mice" Naunyn-Schmiedebergs Archives of Pharmacology. 355. 545-549 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Eguchi,T., Kishi,R.: "Impaired colour discrimination among workers exposed to styrent relavance of a urinary metabolite" Occupational and Environmental Medicine. 52. 534-538 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Yuasa,J., Kishi,R.: "Investigation on neurotoxicity of occupational exposureto to cyclomexane : a neurophysiological study" Occupational and Environmental Medicine. 53. 174-179 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 湯浅潤子, 岸玲子, 原渕泉, 江口照子, 荒田吉彦,他: "末梢神経伝導速度への年齢および皮膚温の影響 職業製曝露作業者の神経機能評価のための基礎的研究" 産衛誌. 38巻. 158-164 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Yuasa J, Kishi R, Eguchi T, Harabuchi I, Arata Y,et al: "Study of urinary Mandelic Acid Concentration and Periphere Nerve Conduction Among Styrene Workers" AMERICAN JOURNAL OF INDUSTRIAL MEDICINE. 30巻. 41-47 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 岸 玲子: "化学物質曝露と精神保健-有機溶剤による影響を中心に-" 産業精神保健. 4巻3号. 208-216 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] WHO Task Group member (Araki,S.): "Inorganic Lead (Environmental Health Criteria 165)" World Health Organization,Geneva,Switzerland, 300 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 荒記 俊一: "'95医学と工学からみた交通安全対策 視認性と安全" 日本交通医学工学研究会, 39-43 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 荒記 俊一: "第3回中国人間工学会学術会議および運転適性に関する神経行動学国際会議論文集" 安徽人民出版社、(合肥、中国), 824-864 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Araki,S.: "Report of The Sixth Coordination Meeting of WHO Qlaborating Centers in Radiation Emergency Medical Preparedness and Assistance Network (REMPAN)" World Health Organization,Geneva,Switzerland, 182-202 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 荒記俊一: "職場環境 新版保健学講座" メヂカルフレンド社, 148-181 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 荒記俊一: "作業関連疾患予防マニュアル作成委員会報告書" 中央労働災害防止協会, 142-164 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Araki, S.: "Assessment of central, peripheral and autonomic nervous system functions in vibrating tool operators : neuroelectrophysiological studies" Environmental Research. 62. 272-282 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Kawakami, N.: "Relations of work stress to alcohol use and drinking problems in male and female employees of a computer factory in japan" Environmental Research. 62. 314-324 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Araki, S.: "Assessment of the effects of occupational and environmental factors on all faster and slower large myelinated nerve fibers : a study of the distribution of nerve conduction velocities" Environmental Research. 62. 325-332 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Sata, F.: "Are faster or slower large myelinated nerve fibers more sensitive to chronic lead exposure? : a study of the distribution of conduction velocities" Environmental Research. 62. 333-338 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Araki, S.: "Decrease of CD4-positive T lymphocytes in workers exposed to benzidine and beta-naphthylamine" Archives of Environmental Health. 48(4). 205-208 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Uchida, E.: "Scioeconomic factors affecting marriage, divorce and birth rates in japanese population" J Biosoc Sci. 25. 499-507 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Ezoe, S.: "Work stress in japanese computer engineers : effcts of computer work or bioeducational factors?" Environmental Research. 63. 148-156 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Murata, K.: "Cardiac autonomic dysfunction in rotogravure printers exposed to toluene in relation to peripheral nerve conduction" Industrial Health. 31. 79-90 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Ezoe, S.: "Assessment of personality traits and psychiatric symptoms in workers in a computer manufacturing plant in japan" American Journal of Industrial Medicine. 25. 187-196 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Murata, K.: "Autonomic neurotoxicity of alcohol assessed by heart rate variability" Journal of the Autonomic Nervous System. 48. 105-111 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Murata, K.: "Changes in autonomic function as determined by ECG R-R interval variability in sandal, shoe, and leather workers exposed to n-hexane, xylene, and toluene" Neuro Toxicology. 15(4). 867-876 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Morita, Y.: "Determination of delta-aminolevulinic acid in plasma using high-performance liquid chromatography : a sensitive indicator of lead effects" Industrial Health. 32. 85-96 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Tanigawa, T.: "Decreases of CD4- and CD8-positive T lymphocytes in retired chromate workers" American Journal of Industrial Medicine. 27. 877-882 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Murata, K.: "Autonomic and central nervous system effects of lead in female glass workers in china" American Journal of Industrial Medicine. 28. 233-244 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Sung, H,L.: "Selective decrease of the suppressor-inducer (CD4+CD45RA+) T lymphocytes in workers exposed to benzidine and beta-naphthylamine" Archives of Environmental Health. 50(3). 196-199 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Kawagami, N.: "Effects of mood states, smoking and urinary catecholamine excretion on hemoglobin Alc in male japanese workers" Industrial Health. 33. 153-162 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Wang, X.: "Effects of smoking on respiratory function and exercise performance in asbestos workers" Industrial Health. 33. 173-180 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Kawagami, N.: "Changes in rates of depressive symptoms in a japanese working population : life-table analysis from a 4-year follow-up study" Psychological Medicine. 25. 1181-1190 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Sata, F.: "Adjustment of creatinine-adjusted values in urine to urinary flow rate : a study of eleven heavy metals and organic substances" Int Arch Occup Environ Health. 68. 64-68 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Kawagami, N.: "Assessment of job stress dimensions based on the job demonds-control model of employees of telecommunication and electric power companies in japan : reliability and validity of the japanese version of the job content questionnaire" International Journal of Behavioral Medicine. 2(4). 358-375 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Murata, K.: "Subclinical impairment in the median nerve across the carpal tunnel among female VDT operators" Int Arch Occup Environ Health. 68. 75-79 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Murata, K.: "Accumulation of VDT work-related visual fatigue assessed by visual evoked potential, near point distance and critical flicker fusion" Industrial Health. 34. 61-69 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Fujimura, Y.: "Changes in the distribution of nerve conduction velocities in diabetics" Tohoku J Exp Med. 178. 177-185 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Araki, S.: "Determination of evoked potentials in occupational and environmental medicine : a review" Environmental Research. 63. 133-147 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Araki, S.: "Application of neurophysiological methods in occupational medicine in relation to psychological performance" Annals Academy of Medicine. 23. 710-718 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Murata,K.: "Subclinical impairment in the median nerve across the carpal tunnel among temale VDT operators" International Archives of Occupational and Environmental Health. 68. 75-79 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Fujmura,Y.: "Changes in the distribution of nerve conduction velocities in diabetics" Tohoku Journal of Experimental Medicine. 178. 177-185 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Tanigawa,T.: "Decreases in subpopulations of lymphocytes and natural killer cells in the blood of retired chromate workers" Interational Journal of Occupational and Environmental Health. 2. 222-225 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Tanigawa,T.: "Increase in CD57+CD16-lymphocytes in workers exposed to benzidine and beta-naphtylamine" International Archives of Occupational and Environmental Health. 69. 69-72 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Tamiya,N.: "Gender difference in the utilization and users' characteristics of community rehabilitation programs for cerebrovascular disease patients in Japan" International Journal for Quality in Health Care. (in press).

    • Related Report
      1996 Annual Research Report
  • [Publications] Yokoyama,K.: "Subsclinical vestibulo-cerebellar,anterior cerebellar lobe and spinocerebellar effects in lead workers in relation to concurrent and past exposure" Neurotoxicology. (in press).

    • Related Report
      1996 Annual Research Report
  • [Publications] Kawakami N,et al.: "A controlled study on effects of a work environment-oriented stress reduction on depressive symptoms in Japanese blue-collar workers." Scandinavian Journal of Work Environment and Health. 23. 54-59 (1997)

    • Related Report
      1996 Annual Research Report
  • [Publications] Kawakami N,et al.: "Occupational factors,smoking habits and tobacco withdrawal symptoms among male Japanese employees." Industrial Health. 35. 9-15 (1997)

    • Related Report
      1996 Annual Research Report
  • [Publications] Kawakami N,et al.: "Prevalence of mood and anxiety disorders in a working population in Japan." Journal of Occupational and Environmental Medicine. 38. 899-905 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Aoki R,et al.: "Life style determinants for social activity levels among the Japanese elderly." Archives of Gerontology and Geriatrics. 22. 261-269 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Kawakami N,et al.: "Reliability and validity of the Japanese version of Job Content Questionnaire:replication and extension in computer company employees." Industrial Health. 34. 295-306 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Kishi,R.: "Effect of prenatal exposur to styrene on the neurobehavioral development,activity,motor co-ordination and learning behavior" Neurotoxicology and teratology. 17-2. 121-130 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] Kawakami N.: "Effects of job strain on helper-inducer(CD4+CD29+)and suppressor-inducer(CD4+CD45RA+)T cells in Japanese blue-collar workers" Psychother Psychosom. (in press).

    • Related Report
      1996 Annual Research Report
  • [Publications] Nakata,A.: "Effects of uncontrollable and controllable electric shocks" Nouroimmunomodulation. (in press).

    • Related Report
      1996 Annual Research Report
  • [Publications] Araki,S: "Neurophysiological methods in occupational and environmental health" Environmental Research. (in press).

    • Related Report
      1996 Annual Research Report
  • [Publications] Araki,S.: "Biobehavioral approach in occupational,environmental and community Health" Journal of Epidemiology. (in press).

    • Related Report
      1996 Annual Research Report
  • [Publications] Kamijma M,Takeuchi Y et al: "Toxic effects of hexane derivatives on enltured rat schwann cells." Toxicol. 108巻. 25-31 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Aiba I,Takeuchi Y et al: "Changes in magnetic re Sonance imaging and olinioal signs in a case of ahronic toluene in toxication by sniffing" J Occup Health. 38巻. 13-19 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Shibata E,Takeuchi Y et al: "Digital nerve conduction velscitios of workers exposed to hevane and toluene." Arch Complex Environ Studies. 7巻. 47-49 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Kondo H,Takeuchi Y et al: "Toluene induces behavional activation without affecting striatal dopamine metabalism in the rat:Behavioral and Microdialysis studies." Pharmacol Biochem Behav. 51巻. 97-101 (1995)

    • Related Report
      1996 Annual Research Report
  • [Publications] Matsuoka M,Matsumura H,Igisu H: "Creatine kinase activities in brain and blood:possible neurotoxic indicator of acrylamide intoxication" Occupational and Environmental Medicine. 53・7. 468-471 (1996)

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      1996 Annual Research Report
  • [Publications] Matsuoka M,Igisu H: "Induction of c-fos expression by tributyltin in PC12 cells:involvement of intracellular Ca^<2+>" Environmental Toxicology and Pharmacology. (発表予定).

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      1996 Annual Research Report
  • [Publications] Matsumura H,Matsuoka M,Igisu H,Ikeda M: "Cooperative inhibition of acetylcholinesterase activities by hexachlorophene in human erythrocytes" Archives of Toxicology. (発表予定).

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      1996 Annual Research Report
  • [Publications] Yu Z,Iryo Y,Matsuoka M Igisu H,Ikeda M: "Suppression of pentylenetetrazol-induced seizures by carnitine in mice" Naunyn-Schmiedebergs Archives of Pharmacology. (発表予定).

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      1996 Annual Research Report
  • [Publications] Eguchi,T.,Kishi,R.: "Impaired colour discrimination among workers exposed to styrent relavance of a urinary metabolite" Occupational and Environmental Medicine. 52. 534-538 (1995)

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      1996 Annual Research Report
  • [Publications] Yuasa,J.,Kish,R.: "Investigation on neurotoxicity of occupational exposure to cyclonexane;a neurophysiological study" Occupational and Environmental Medicine. 53. 174-179 (1996)

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      1996 Annual Research Report
  • [Publications] 湯浅潤子,岸 玲子,原渕泉 江口照子,荒田吉彦,他,: "末梢神経伝導速度への年齢および皮膚温の影響 職業性曝露作業者の神経機能評価のための基礎的研究" 産衛誌. 38巻. 158-164 (1996)

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      1996 Annual Research Report
  • [Publications] Yuasa J,Kishi R,Eguchi T,Harabuchi I,Arata Y,et al: "Study of urinary Mandelic Acid Concentration and Peripheral Nerve Conduction Among Styrene Workers" AMERICAN JOURNAL OF INDUSTRIAL MEDICINE. 30巻. 41-47 (1996)

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      1996 Annual Research Report
  • [Publications] 岸 玲子: "化学物質曝露と精神保健-有機溶剤による影響を中心に-" 産業精神保健. 4巻3号. 208-216 (1996)

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      1996 Annual Research Report
  • [Publications] WHO Task Group member(Araki,S.): "Inorganic Lead(Environmental Health Criteria 165)" World Health Organization,Geneva,Switzerland, 300 (1995)

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      1996 Annual Research Report
  • [Publications] 荒記 俊一: "'95医学と工学からみた交通安全対策 視認性と安全" 日本交通医学工学研究会, 39-43 (1995)

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      1996 Annual Research Report
  • [Publications] 荒記 俊一: "職場環境 新版保健学講座" メヂカルフレンド社(印刷中),

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      1996 Annual Research Report
  • [Publications] 荒記 俊一: "内科診断学第8版" 金芳堂,京都(印刷中),

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      1996 Annual Research Report
  • [Publications] 荒記 俊一: "第3回中国人間工学会学術会議および運転適性に関する神経行動学国際会議論文集" 安徽人民出版社,(合肥,中国), 55 (1995)

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      1996 Annual Research Report
  • [Publications] Araki,S.: "Report of The Sixth Coordination Meeting of WHO Collaborating Centers in Radiation Emergency Medical Preparedness and Assistance Network(REMPAN)" World Health Organization,Geneva,Switzerland, 20 (1996)

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      1996 Annual Research Report
  • [Publications] 荒記 俊一: "新臨床内科学第7版" 医学書院(印刷中),

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      1996 Annual Research Report
  • [Publications] 荒記 俊一: "新臨床内科学-コンパクト版" 医学書院(印刷中),

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      1996 Annual Research Report
  • [Publications] Wang, X.,: "Dyspnea and exercise testing in workers exposed to silica." Industrial Health. 33. 163-171 (1995)

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      1995 Annual Research Report
  • [Publications] Wang, X.,: "Effects of smoking on respiratory function and exercise performance in asbestos workers." Industrial Health. 33. 173-180 (1995)

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      1995 Annual Research Report
  • [Publications] Imanaka, Y.,: "Patient judgment of the quality of ambulatory care in a Japanese setting." Clinical Performance and Quality Health Care. 3. 197-208 (1995)

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      1995 Annual Research Report
  • [Publications] Sata, F.,: "Adjustment of creatine-adjusted values in urine to urinary flow rate: A study to eleven heavy metals and organic substances." International Archives of Occupational and Environmental Health. 68. 64-68 (1995)

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      1995 Annual Research Report
  • [Publications] Morita, Y.,: "A reference value for delta-aminolevulinic acid in plasma in population occupationally unexposed to lead." Industrial Health. 34. 57-60 (1996)

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      1995 Annual Research Report
  • [Publications] Kawakami, N.,: "Changes in rates of depressive symptoms in a Japanese working population: Lite-table analysis from a 4-year follow-up study." Psychological Medicine. 25. 1181-1190 (1995)

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      1995 Annual Research Report
  • [Publications] Murata, K.,: "Subclinical impairment in the median nerve across the carpal tunnel among female VDT operators." International Archives of Occupational and Environmental Health. (in press).

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      1995 Annual Research Report
  • [Publications] Sata, F.,: "Adjustment of creatinine-adjusted value to flow rate in rate in lead workers." Archives of Environmental Health. (in press).

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      1995 Annual Research Report
  • [Publications] Kawakami, N.,: "Assessment of job stress dimensions based on the job demands-control model in employees of telecommunication and electricpower companies in Japan" International Journal of Behavioral Medicine. (in press).

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      1995 Annual Research Report
  • [Publications] Murata, K.,: "Accmulation of VDT work-related visual fatigue assessed by visual evoked potential, near point distance and critical flicker fusion." Industrial Health. (in press).

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      1995 Annual Research Report
  • [Publications] 佐藤元: "慢性関節リウマチ患者のQOLと患者の主観的健康感・生活満足度との関係について" 日本公衆衛生雑誌. 42. 743-754 (1995)

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      1995 Annual Research Report
  • [Publications] 岡島史佳: "エイズ(AIDS)患者の診断体制に関する研究-東京都エイズ研究班の病院調査より-" 日本公衆衛生雑誌. 42. 799-807 (1995)

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      1995 Annual Research Report
  • [Publications] 荒記俊一: "魚多食集団における有機水銀汚染-フェロ-諸島" 公衆衛生. 59. 321-324 (1995)

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      1995 Annual Research Report
  • [Publications] 荒記俊一: "環境因子による非顕性の神経・精神行動障害の評価と最近の知見" 日本衛生学雑誌. 50. 713-729 (1995)

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  • [Publications] 荒記俊一: "日本行動医学会(JSBM)の創立と初期の活動-国際行動医学会の流れより-" 行動医学研究. 2. 12-19 (1995)

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  • [Publications] 北村文彦: "産業保健と分子生物学-職業癌および環境癌へのアプローチ" 公衆衛生. 59. 851-854 (1995)

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  • [Publications] 荒記俊一: "産業神経中毒と精神生理学-ICOH,WHO,IPCS,ILO,ECなどの取組み" 公衆衛生. 60. 1-6 (1996)

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  • [Publications] Kondo H, Huang J, Ichihara G, Takeuchi Y, Nakahara D.: "Toluene induces behavioral activation without affecting striatal dopamine metabolism in the rat Behavioral and microdialysis studies." Pharmacol Biochem Behav. 51. 97-101 (1995)

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      1995 Annual Research Report
  • [Publications] Kawakami N, et al.: "Effects of mood states, smoking and urinary catecholamine excretion on hemoglobin Alc in male Japanese workers" Industrial Health. 33. 153-162 (1995)

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      1995 Annual Research Report
  • [Publications] Kawakami N, et al.: "Job stress characteristics of computer work in Japan" Anzai Y et al. (eds.) Symbiosis of human and artifact Elsevier Science. B. V.: Amsterdam. 705-710 (1995)

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      1995 Annual Research Report
  • [Publications] Kawakami N, et al.: "Changes in rates of depressive symptoms in a Japanese working population: life-table analysis from a 4-year follow-up study" Psychological Medicine. 25. 1181-1190 (1995)

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      1995 Annual Research Report
  • [Publications] Iwata N, Roberts CR Kawakami N: "Japan-U. S. comparison of responses to depression scale items among adult workers" Psychiatry Research. 58. 237-245 (1995)

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      1995 Annual Research Report
  • [Publications] Hayashi T, Kawakami N, et al.: "Prevalence of and risk factors for allergic diseases: comparison of two cities in Japan" Annals of Allergy, Asthma, & Immunology. 75. 525-529 (1995)

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      1995 Annual Research Report
  • [Publications] Kawakami N, et al.: "Assessment of job stress dimensions based on the Job Demands-Control Model in employees of telecommunication and electric power companies in Japan" Int J Behavioral Medicine. (in press).

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      1995 Annual Research Report
  • [Publications] Yuasa, J.: "Investigation on neurotoxicity of occupational exposure to cyclohexane: neurophysiological study" Occu. Environ Med 1996. (in press).

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      1995 Annual Research Report
  • [Publications] Eguchi, T: "Impaired colour discrimination among workers exposed to styrene: relevance of a urinary" Occu Environ Med. 52. 534-538 (1995)

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      1995 Annual Research Report
  • [Publications] Yuasa, J: "A Study of urinary mandelic acid concentration and peripheral nerve conduction among styrene workers" Occu Environ Med. (in press).

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      1995 Annual Research Report
  • [Publications] 佐藤紀: "麻酔科医の疲労度とストレスに関する調査" 麻酔. 44. 674-678 (1995)

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      1995 Annual Research Report
  • [Publications] Kish, R.: "Effect of prenatal exposuve to styrene on the neurobehavioral development, activity, motor coordination and lcarning behavior of rat" Neurotoxicology and Teratology. 17. 130-140 (1995)

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      1995 Annual Research Report
  • [Publications] 荒記俊一: "産業保健マニュアル(第3版)" 南山堂, 4 (1995)

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      1995 Annual Research Report
  • [Publications] 荒記俊一: "作業関連疾患予防マニュアル(案)" 中央労働災害防止協会, 24 (1995)

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      1995 Annual Research Report
  • [Publications] 多田羅浩三: "公衆衛生資料集NO.4" 日本公衆衛生協会, 156 (1995)

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      1995 Annual Research Report
  • [Publications] 多田羅浩三: "脳卒中発症者に対する地域ケアネットワークの確立" 日本公衆衛生協会, 13 (1995)

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Published: 1996-04-01   Modified: 2016-04-21  

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