Analysis of higher cortical function using transcranial magnetic stimulation
| Project/Area Number |
07409012
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (A)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
広領域
|
|---|
| Research Institution | The University of Tokyo |
|---|
Principal Investigator |
SUGISHITA Morihiro University of tokyo, Faculty of Medicine, Prof, 医学部, 教授 (10114513)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
TAKAYAMA Yoshihiro University of tokyo, Faculty of Medicine, Lecturer, 医学部, 講師 (20250201)
|
|---|
| Project Period (FY) |
1995 – 1996
|
| Project Status |
Completed (Fiscal Year 1996)
|
| Budget Amount *help |
¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 1996: ¥2,000,000 (Direct Cost: ¥2,000,000)
|
|---|
| Keywords | repetitive magnetic stimulation / magnetic stimulation / higher cortical function / eye mouement / language / vision |
|---|
| Research Abstract |
Experiment 1
Discrete steps of the target induce apparent motion sensation. This phenomena is called beta-motion. Recent studies showed that motion perception was processed at V5 which was at the junction of temporal and occipital lobes. To investigate whether beta-motion is related to V5, we applied repetitive transcranial magnetic stimulaiton to V5 while the subjects experienced beta-motion sensation. As a result, we could not find any effect on beta-motion sensation.
Experiment 2
A hypothesis says that motion aftereffect occurs because of the fatigue of visual-related neurons. Some studies with repetitive transcranal magnetic stimulation indicate that repetitive stimulation reduce the threshold of neuronal activities. If so, repetitive stimulation could have some effect on visual illusion when it was applied to illusion-related region. To investigate this hypothesis, we applied repetitive transcranial magnetic stimulation to the parietal lobe, the temporal lobe, the occipital lobe. How
… More
ever, we could not induce any effects on motion aftereffect.
Experiment 3
When we read a letter, it is assumed that the inlet of the brain is the occipital lobe and the out-let is the frontal lobe. To ascertain this, we applied repetitive transcranial magnetic stimulation to the left frontal lobe when the subject tried to read out one Kana character and measured the reaction time. We found the tendency of delay of reaction time when the stimulation applied 100msec after the visual presentation of a character.
We planned to apply repetitive transcranial magnetic stimulation, because single stimulation is reported to be difficult to induce any effects on higher cognitive function. Our experiment also have failed to induce prominent effect. One reason might be the weakness of the applied stimulation. It was reported thatrepetitive transcranial magnetic induced generalized seizure. As there is no strict criteria of repetitive transcranial magnetic stimulation, we hesitated to apply stronger stimuli. To use this technique further, it is essential to establish the safety criteria. Less
|
Report
(3 results)
Research Products
(17 results)
